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2024-05-19 20:57:48

Gene list

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COG category: Signal transduction mechanisms
Organism: Dictyostelium lacteum

Number of genes found: 357

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Dictyostelium lacteum
NameLocus tagProduct / DescriptionGenomic elementTypeBeginLengthStrandGC-content
g10022 DLA_11184 GLQOFTK02JL55Q CDS639909 2118 - 0.315392
g10043 DLA_11206 GLQOFTK02JL55Q CDS683801 1260 - 0.281746
g10044 DLA_11207 GLQOFTK02JL55Q CDS685183 1239 - 0.297014
g10075 DLA_11248 GLQOFTK02JL55Q CDS756239 1938 + 0.288958
g10078 DLA_11251 GLQOFTK02JL55Q CDS762875 3936 + 0.306657
g10086 DLA_11259 GLQOFTK02JL55Q CDS780755 444 + 0.31982
g10100 DLA_11276 localizes to the cell cortex binds myosin II and regulates microtubule length the cortical cytoskeleton and cytokinesis functions in the same pathway as racE to regulate these processesGLQOFTK02JL55Q CDS811197 741 - 0.368421
g10106 DLA_11284 GLQOFTK02JL55Q CDS823910 2478 + 0.307103
g10127 DLA_11309 GLQOFTK02JL55Q CDS869532 4638 + 0.335058
g10222 DLA_11418 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationnewcontig00824_1.exp CDS58027 1758 + 0.306598
g1040 DLA_01150 F4PJNLW01A00V1 CDS904204 1107 - 0.31617
g1067 DLA_01175 F4PJNLW01A00V1 CDS966915 1383 - 0.339118
g1097 DLA_01213 F4PJNLW01A00V1 CDS1034101 2148 - 0.366853
g1115 DLA_01232 F4PJNLW01A00V1 CDS1092890 2142 + 0.332866
g1167 DLA_01284 F4PJNLW01A00V1 CDS1225330 4419 - 0.342838
g1236 DLA_01359 protein serinethreonine kinase homologous to human Nek2 kinase involved in formation of microtubule-organizing centers (MTOCs)F4PJNLW01A00V1 CDS1401955 1134 - 0.308642
g1302 DLA_01426 putative protein serinethreonine kinase the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases stress-responsive kinaseF4PJNLW01B0TO9 CDS27222 3570 + 0.333333
g1322 DLA_01446 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinasesF4PJNLW01B0TO9 CDS66765 1326 - 0.33635
g1348 DLA_01478 putative protein serinethreonine kinase GSK family member of the CMGC kinase group similar to Drosophila shaggy and other glycogen synthase kinasesF4PJNLW01B0TO9 CDS135859 1329 - 0.346877
g1373 DLA_01505 F4PJNLW01B0TO9 CDS188605 4566 - 0.318003
g1387 DLA_11481 F4PJNLW01B0TO9 CDS220295 465 + 0.378495
g1413 DLA_01549 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationF4PJNLW01B0TO9 CDS268569 1326 - 0.36727
g142 DLA_00165 contig05409_1.exp CDS332861 1857 + 0.325256
g144 DLA_00167 contig05409_1.exp CDS337749 2379 - 0.349306
g1549 DLA_11488 F4PJNLW01B0TO9 CDS580805 2460 + 0.387398
g1550 DLA_01697 F4PJNLW01B0TO9 CDS583710 5862 + 0.360628
g1606 DLA_01758 F4PJNLW01B0TO9 CDS707303 1743 - 0.327022
g162 DLA_00188 contig05409_1.exp CDS376542 1929 + 0.369103
g1635 DLA_01790 F4PJNLW01B0TO9 CDS765011 3840 - 0.359635
g1664 DLA_01820 F4PJNLW01B0TO9 CDS835697 6819 + 0.307816
g1665 DLA_01821 F4PJNLW01B0TO9 CDS842624 606 - 0.293729
g1668 DLA_01824 F4PJNLW01B0TO9 CDS846981 2520 + 0.289286
g1697 DLA_01857 F4PJNLW01B0TO9 CDS918129 1437 - 0.347251
g1701 DLA_01861 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinaseF4PJNLW01B0TO9 CDS929551 2454 + 0.332926
g1728 DLA_01892 F4PJNLW01B0TO9 CDS988245 3060 + 0.32451
g1734 DLA_01899 F4PJNLW01B0TO9 CDS1004895 2139 - 0.322113
g1790 DLA_01953 F4PJNLW01C9MXC CDS59749 2139 - 0.320243
g1794 DLA_01957 F4PJNLW01C9MXC CDS67445 2940 + 0.339796
g1801 DLA_01964 F4PJNLW01C9MXC CDS86554 222 - 0.31982
g1819 DLA_01984 F4PJNLW01C9MXC CDS134212 2448 + 0.33415
g1833 DLA_01998 F4PJNLW01C9MXC CDS161915 1767 + 0.367855
g1889 DLA_02061 F4PJNLW01CH19P CDS96374 2988 - 0.351406
g1898 DLA_11513 F4PJNLW01DERRH CDS15159 2400 + 0.26375
g1909 DLA_02083 F4PJNLW01DERRH CDS52075 2175 - 0.308506
g1935 DLA_02117 F4PJNLW01DERRH CDS124838 2322 - 0.314384
g2022 DLA_02221 member of the TKL (tyrosine kinase-like) group contains a galactose oxidase central domain and three Kelch motifsF4PJNLW01DERRH CDS331361 3084 + 0.336576
g2049 DLA_02252 F4PJNLW01DERRH CDS385220 5760 + 0.336111
g2067 DLA_02273 protein serinethreonine phosphatase required for chemotaxis and development suppresses the F4PJNLW01DERRH CDS424814 915 - 0.339891
g210 DLA_00235 contig05409_1.exp CDS490745 477 - 0.278826
g2102 DLA_02316 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationF4PJNLW01DERRH CDS492601 1605 + 0.316511
g2124 DLA_02339 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW01DERRH CDS552865 1164 - 0.34622
g2142 DLA_02357 F4PJNLW01DERRH CDS587571 909 - 0.354235
g2162 DLA_02380 member of the AGC kinase group similar to kinase domains of NDR (nuclear Dbf2-related) and MAST (microtubule-associated serinethreonine kinase)F4PJNLW01DERRH CDS633835 4887 + 0.331492
g2173 DLA_02393 F4PJNLW01DERRH CDS660867 1635 + 0.310703
g219 DLA_00243 conserved low molecular weight phosphotyrosine protein phosphatase acts on tyrosine phosphorylated proteins low-MW aryl phosphates and natural and synthetic acyl phosphatescontig05409_1.exp CDS504881 534 + 0.299625
g2206 DLA_02429 F4PJNLW01EE5MJ CDS154 1812 + 0.312362
g2239 DLA_02473 dual specificity phosphatases remove phosphate groups from tyrosine and serinethreonine residuesF4PJNLW01EE5MJ CDS89204 498 + 0.359438
g2260 DLA_02495 F4PJNLW01EE5MJ CDS138880 2247 - 0.365821
g2269 DLA_02508 F4PJNLW01EE5MJ CDS174693 1038 + 0.266859
g2276 DLA_02517 F4PJNLW01EE5MJ CDS187796 369 + 0.289973
g2305 DLA_02548 F4PJNLW01EE5MJ CDS256752 3549 - 0.31051
g2306 DLA_02550 F4PJNLW01EE5MJ CDS260902 897 - 0.338907
g2359 DLA_02609 F4PJNLW01EE5MJ CDS357944 339 - 0.312684
g237 DLA_00264 contig05409_1.exp CDS540310 1800 - 0.360556
g2381 DLA_02636 F4PJNLW01EE5MJ CDS406795 3672 + 0.353214
g2385 DLA_02640 catalytic subunit of the Casup2supcalmodulin-dependent serinethreonine protein phosphataseF4PJNLW01EE5MJ CDS416797 1710 + 0.330994
g24 DLA_00028 contig05409_1.exp CDS61377 3906 - 0.323605
g2432 DLA_02697 F4PJNLW01EE5MJ CDS519322 3981 + 0.373524
g245 DLA_00272 contig05409_1.exp CDS557093 1836 - 0.283769
g2455 DLA_02725 F4PJNLW01EE5MJ CDS579082 2658 - 0.322047
g2467 DLA_02737 F4PJNLW01EE5MJ CDS614224 2649 + 0.348056
g2488 DLA_02759 F4PJNLW01EE5MJ CDS667342 6816 + 0.359008
g2514 DLA_02788 F4PJNLW01EE5MJ CDS721035 2421 + 0.327551
g2520 DLA_02794 F4PJNLW01EE5MJ CDS732818 813 - 0.341943
g2542 DLA_02816 F4PJNLW01EE5MJ CDS781075 2442 + 0.285831
g2578 DLA_02861 F4PJNLW01EE5MJ CDS864104 2604 - 0.320276
g2594 DLA_02877 F4PJNLW01EE5MJ CDS918769 3492 + 0.340779
g2620 DLA_02908 F4PJNLW01EE5MJ CDS969208 3174 - 0.333018
g2636 DLA_02926 F4PJNLW01EE5MJ CDS1000811 2118 - 0.344193
g2653 DLA_02945 F4PJNLW01EE5MJ CDS1040175 618 - 0.326861
g2657 DLA_02949 F4PJNLW01EE5MJ CDS1044784 1410 - 0.338298
g270 DLA_00300 contig05409_1.exp CDS625941 2418 + 0.35732
g2705 DLA_02999 F4PJNLW01EE5MJ CDS1138608 2625 - 0.299429
g2711 DLA_03007 F4PJNLW01EE5MJ CDS1148480 1926 + 0.286085
g2720 DLA_03016 F4PJNLW01EE5MJ CDS1170267 1944 + 0.314815
g2728 DLA_03023 F4PJNLW01EE5MJ CDS1186112 7353 - 0.300286
g2739 DLA_03035 F4PJNLW01EE5MJ CDS1213710 1593 + 0.338983
g2824 DLA_03127 F4PJNLW02GJ9ZB CDS146833 2541 - 0.245179
g2825 DLA_03128 similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases predicted to activate SG2 cyclins cyclin A B and DF4PJNLW02GJ9ZB CDS150193 900 + 0.331111
g2845 DLA_03151 F4PJNLW02GJ9ZB CDS197599 3150 + 0.292064
g2921 DLA_03236 F4PJNLW02HBBIY CDS97770 1467 - 0.334015
g2924 DLA_03239 F4PJNLW02HBBIY CDS103863 957 - 0.345873
g2927 DLA_03242 F4PJNLW02HBBIY CDS108985 1764 - 0.3322
g2942 DLA_03260 F4PJNLW02HBBIY CDS138381 11952 + 0.347808
g2958 DLA_03279 F4PJNLW02HBBIY CDS186711 555 - 0.313514
g3035 DLA_03362 F4PJNLW02HBBIY CDS361414 2673 + 0.34306
g3037 DLA_03363 F4PJNLW02HBBIY CDS366615 2451 - 0.339861
g3043 DLA_03369 F4PJNLW02HBBIY CDS378053 4266 - 0.339897
g3045 DLA_03370 F4PJNLW02HBBIY CDS384208 672 - 0.33631
g3061 DLA_03388 F4PJNLW02HBBIY CDS422744 2760 + 0.350362
g3113 DLA_03447 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW02HBBIY CDS518303 1077 + 0.287837
g315 DLA_00350 contig05409_1.exp CDS728057 2577 - 0.327901
g3216 DLA_11554 CK2 family protein kinase a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to caseinGAOABQK02FWKR3 CDS32017 1611 - 0.306021
g3232 DLA_03581 GAOABQK02G6SYV CDS10896 894 - 0.394855
g3298 DLA_03649 GAOABQK02G6SYV CDS161683 453 - 0.337748
g3322 DLA_03673 GAOABQK02G6SYV CDS207498 4548 + 0.348505
g3350 DLA_03706 GAOABQK02G6SYV CDS264850 3468 - 0.364475
g3405 DLA_03766 GAOABQK02G6SYV CDS380671 1143 + 0.32021
g3412 DLA_03775 GAOABQK02G6SYV CDS393352 3546 + 0.368302
g3497 DLA_03875 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GAOABQK02G6SYV CDS594795 1926 - 0.339564
g3537 DLA_03916 STE SerThr protein kinase family mitogen-activated protein kinase kinase involved in chemotaxis and early development phosphorylates the MAP kinase Erk1 (erkA) is sumoyalated by sumo and ubiquinated by mip1GAOABQK02G6SYV CDS686979 1284 - 0.323209
g3549 DLA_03930 GAOABQK02G7M1S CDS12808 2847 + 0.334387
g3557 DLA_03937 GAOABQK02G7M1S CDS30188 774 + 0.352713
g3558 DLA_03938 GAOABQK02G7M1S CDS31797 4113 + 0.292001
g3568 DLA_03952 GAOABQK02G7M1S CDS71620 3717 + 0.312618
g3587 DLA_03974 GAOABQK02G7M1S CDS120773 726 - 0.318182
g3644 DLA_04041 GAOABQK02G7M1S CDS250249 3735 - 0.326104
g3664 DLA_04060 GAOABQK02G7M1S CDS303809 1908 + 0.343816
g3713 DLA_04114 similar to Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) contains one SH3 (src Homology-3) domainGAOABQK02G7M1S CDS413945 2100 + 0.350952
g3741 DLA_04144 GAOABQK02G7M1S CDS471893 2535 - 0.341223
g3784 DLA_04196 GAOABQK02G7M1S CDS566511 1071 + 0.345472
g3799 DLA_04213 GAOABQK02G7M1S CDS604665 1314 + 0.362253
g3807 DLA_04222 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase rasGAOABQK02G7M1S CDS617133 4275 - 0.349942
g3830 DLA_04248 GAOABQK02G7M1S CDS681315 441 - 0.321995
g3864 DLA_04284 GAOABQK02G7M1S CDS761256 1530 + 0.336601
g3877 DLA_04298 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family expressed in pstO cellsGAOABQK02GQAQJ CDS20246 1581 + 0.31246
g3923 DLA_04350 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesisGAOABQK02GQAQJ CDS129732 1560 + 0.350641
g3926 DLA_04353 GAOABQK02GQAQJ CDS136067 750 + 0.342667
g3934 DLA_04363 GAOABQK02GQAQJ CDS151071 2484 + 0.355878
g3962 DLA_04391 GAOABQK02GQAQJ CDS209901 624 - 0.355769
g398 DLA_00442 contig05409_1.exp CDS911085 2340 + 0.334188
g4011 DLA_04450 GAOABQK02GQAQJ CDS329479 546 + 0.358974
g4012 DLA_04451 GAOABQK02GQAQJ CDS330396 939 - 0.342918
g4035 DLA_04475 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosisGAOABQK02GQAQJ CDS383387 1971 - 0.33587
g4037 DLA_04478 GAOABQK02GQAQJ CDS388513 2502 + 0.328137
g4065 DLA_04509 GAOABQK02GQAQJ CDS450958 357 + 0.333333
g4145 DLA_04594 ortholog of the human PPP2R4 (PTPA) that stimulates the phosphotyrosyl phosphatase activity of PP2A in the presence of ATP and Mg(2) in vitroGAOABQK02GQAQJ CDS604651 963 - 0.345794
g4149 DLA_04597 GAOABQK02GQAQJ CDS611526 2625 - 0.32419
g415 DLA_00460 contig05409_1.exp CDS945875 1254 + 0.339713
g4158 DLA_04605 GAOABQK02GQAQJ CDS630116 7644 + 0.354003
g4163 DLA_04610 GAOABQK02GQAQJ CDS643235 2076 - 0.307803
g4205 DLA_04650 contains a sac phosphatase domain similar to D. discoideum sac1 similar to D. purpureum proteinGAOABQK02GQAQJ CDS723389 3156 - 0.295627
g4216 DLA_04663 GAOABQK02GQAQJ CDS744357 2100 + 0.32
g4218 DLA_04665 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinasesGAOABQK02GQAQJ CDS751139 1023 - 0.362659
g4225 DLA_04672 GAOABQK02GQAQJ CDS770362 2007 - 0.337319
g4234 DLA_04682 GAOABQK02GQAQJ CDS789545 1029 - 0.316812
g4271 DLA_04716 GAOABQK02GQAQJ CDS869762 8682 - 0.349804
g4293 DLA_04739 GAOABQK02GQAQJ CDS925019 1179 - 0.318066
g4303 DLA_04749 GAOABQK02GQAQJ CDS952334 1602 + 0.338951
g4315 DLA_04763 GAOABQK02GQAQJ CDS981628 726 + 0.285124
g4336 DLA_04789 GAOABQK02GQAQJ CDS1046815 4053 + 0.339255
g4361 DLA_04820 GAOABQK02GRIAE CDS17839 2421 - 0.336225
g4362 DLA_04821 GAOABQK02GRIAE CDS20539 2247 - 0.315532
g4412 DLA_04878 GAOABQK02GRIAE CDS155358 4623 + 0.307376
g446 DLA_00493 contig05409_1.exp CDS1022388 2244 - 0.3418
g4548 DLA_05040 CK2 family protein kinase a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to caseinGAOABQK02H81I9 CDS251379 1047 + 0.325692
g4554 DLA_05047 GAOABQK02H81I9 CDS260609 963 - 0.364486
g4592 DLA_05087 GAOABQK02H81I9 CDS346046 441 + 0.324263
g4604 DLA_05099 GAOABQK02H81I9 CDS375330 2349 + 0.325671
g4618 DLA_05115 GAOABQK02H81I9 CDS409558 4971 - 0.345001
g4628 DLA_05125 GAOABQK02H81I9 CDS434500 4944 + 0.344053
g4629 DLA_05126 GAOABQK02H81I9 CDS440362 2097 - 0.379113
g4699 DLA_05203 GAOABQK02H81I9 CDS597680 2328 - 0.341065
g4769 DLA_05278 GAOABQK02H81I9 CDS774378 2373 - 0.334598
g4784 DLA_05295 GAOABQK02H81I9 CDS806986 5853 - 0.320178
g479 DLA_00531 contig05409_1.exp CDS1098948 4128 + 0.349806
g4811 DLA_05328 GAOABQK02H81I9 CDS864922 1761 + 0.284497
g4816 DLA_05332 GAOABQK02H81I9 CDS873335 2250 - 0.326667
g4855 DLA_05376 GAOABQK02HUB3S CDS69940 2490 + 0.326908
g4863 DLA_05385 GAOABQK02HUB3S CDS82935 5202 + 0.328143
g4886 DLA_05410 GAOABQK02HUB3S CDS144754 3432 + 0.33042
g4887 DLA_05411 GAOABQK02HUB3S CDS148443 1041 - 0.329491
g4888 DLA_05412 GAOABQK02HUB3S CDS149655 492 - 0.302846
g4925 DLA_05453 GAOABQK02HUB3S CDS236552 2322 - 0.306632
g4991 DLA_05525 GAOABQK02HUB3S CDS383190 1203 - 0.320033
g5001 DLA_05538 GAOABQK02HUB3S CDS401139 1557 + 0.326268
g501 DLA_00554 contig05409_1.exp CDS1147813 1587 + 0.328923
g5021 DLA_05560 GAOABQK02HUB3S CDS434802 7788 - 0.351181
g5059 DLA_05599 GAOABQK02HUB3S CDS526810 1863 - 0.3489
g5070 DLA_05615 GAOABQK02HUB3S CDS553749 6030 - 0.315091
g5073 DLA_05618 GAOABQK02HUB3S CDS562805 2460 - 0.314634
g5087 DLA_05635 GAOABQK02HUB3S CDS593660 1707 - 0.313415
g5108 DLA_05657 GAOABQK02HUB3S CDS648858 2475 - 0.298586
g5142 DLA_05702 GAOABQK02HUB3S CDS733229 2988 - 0.282798
g5200 DLA_05772 GAOABQK02HUB3S CDS915455 2523 + 0.349187
g5285 DLA_05866 GAOABQK02HUB3S CDS1120661 2448 - 0.330474
g529 DLA_00582 contig05409_1.exp CDS1207838 4317 + 0.351633
g5310 DLA_05900 GAOABQK02HUB3S CDS1179641 2886 + 0.288635
g5336 DLA_05934 GAOABQK02HUB3S CDS1241031 3873 + 0.32662
g5354 DLA_05956 contains a cyclase domain 7 transmembrane helices a histidine kinase domain and two receiver domainsGAOABQK02HUB3S CDS1277865 4821 - 0.340178
g5417 DLA_06029 GAOABQK02HUB3S CDS1428820 2505 - 0.30978
g5428 DLA_06042 GAOABQK02HUB3S CDS1453817 2178 + 0.305785
g5433 DLA_06049 GAOABQK02HUB3S CDS1461570 2115 - 0.340898
g5445 DLA_06065 GAOABQK02HUB3S CDS1494646 993 + 0.316213
g5448 DLA_06068 GAOABQK02HUB3S CDS1502068 3438 - 0.331006
g5468 DLA_06093 GAOABQK02HUB3S CDS1546733 414 - 0.330918
g5536 DLA_06168 GAOABQK02HUB3S CDS1705673 1164 + 0.311856
g561 DLA_00617 contig05409_1.exp CDS1280986 912 - 0.358553
g5647 DLA_06294 GAOABQK02IBA3P CDS85170 930 - 0.291398
g5654 DLA_06300 GAOABQK02IBA3P CDS100124 4236 - 0.344901
g5666 DLA_06312 catalytic subunit of the Casup2supcalmodulin-dependent serinethreonine protein phosphataseGAOABQK02IBA3P CDS133718 1569 + 0.333971
g5752 DLA_06415 GAOABQK02IBA3P CDS362764 1143 - 0.339458
g5793 DLA_06460 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinaseGAOABQK02IBA3P CDS453719 2019 - 0.327885
g5842 DLA_06516 GAOABQK02IBA3P CDS553910 3255 - 0.349309
g5959 DLA_11661 GAOABQK02IBA3P CDS839364 762 - 0.368766
g6002 DLA_06684 GAOABQK02IBA3P CDS951201 2358 - 0.337574
g6006 DLA_06687 GAOABQK02IBA3P CDS962016 2868 - 0.331939
g6024 DLA_06711 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domainsGAOABQK02IBA3P CDS1003562 5019 - 0.328751
g6055 DLA_06742 similar to Dictyostelium pakA and other mitogen-activated protein kinases (Ste20PAK family) putative p21-activated kinase contains a calponin-like actin-binding domain a p21-Rho-binding domain and a PKC conserved region 1 (C1) regulates the actin cytoskeleton response during chemotaxis to cAMPGAOABQK02IBA3P CDS1064531 3954 + 0.309054
g6066 DLA_06753 inositol 5-phosphatase similar to the human protein OCRL which when defect causes Lowe syndrome involved in Dictyostelium growth development and phagocytosisGAOABQK02IBA3P CDS1087916 2187 + 0.328761
g6079 DLA_06767 GAOABQK02IBA3P CDS1121898 2040 - 0.323039
g6083 DLA_06771 GAOABQK02INHKB CDS9919 3717 - 0.313963
g6136 DLA_06835 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GAOABQK02IO52T CDS102489 4140 - 0.322947
g6149 DLA_06849 GAOABQK02IO52T CDS138582 3204 + 0.334582
g6184 DLA_06894 GAOABQK02IO52T CDS205344 4128 + 0.341328
g6260 DLA_06974 GAOABQK02IO52T CDS373105 1275 + 0.294902
g6268 DLA_06982 GAOABQK02IO52T CDS386719 1077 - 0.301764
g6276 DLA_06991 GAOABQK02IO52T CDS405378 1617 - 0.31107
g6364 DLA_07084 GAOABQK02IO52T CDS593010 2448 - 0.329657
g6367 DLA_07087 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinaseGAOABQK02IO52T CDS603199 2982 + 0.346412
g6393 DLA_07114 putative protein serinethreonine kinase N-terminus similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase C-terminal half belongs to the peptidase C2 family contains 4 calpain III domains and has similarity to calpain-like cysteine proteaseGAOABQK02IO52T CDS657826 3318 + 0.347499
g6396 DLA_07117 controls RNA polymerase II activity by phosphorylating the carboxy terminal domain (CTD) of the largest subunit predicted to interact with GAOABQK02IO52T CDS663556 1113 + 0.343217
g6433 DLA_07159 GAOABQK02JBK0O CDS45121 2970 - 0.306734
g6466 DLA_07195 GAOABQK02JBK0O CDS130705 501 - 0.315369
g6497 DLA_07234 GAOABQK02JEBFV CDS45755 2196 - 0.331056
g651 DLA_00720 F4PJNLW01A00V1 CDS34648 1248 - 0.309295
g6524 DLA_07265 GAOABQK02JOCCH CDS48097 3072 + 0.277995
g6529 DLA_07270 GAOABQK02JOCCH CDS58644 1905 - 0.290814
g6566 DLA_07317 contains 5 transmembrane domains there is a second copy of this gene GAOABQK02JOCCH CDS152486 705 + 0.339007
g6568 DLA_07319 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationGAOABQK02JOCCH CDS155446 1314 + 0.350837
g6607 DLA_07358 GAOABQK02JOCCH CDS240004 12681 - 0.328365
g6636 DLA_07391 GAOABQK02JOCCH CDS319799 5493 + 0.298744
g6674 DLA_07435 GAOABQK02JOCCH CDS403183 3987 + 0.346627
g6679 DLA_07439 GAOABQK02JOCCH CDS414241 1386 - 0.368687
g6686 DLA_07446 GAOABQK02JOCCH CDS428514 2859 - 0.317943
g6711 DLA_07474 GAOABQK02JOCCH CDS471109 7059 - 0.374982
g6712 DLA_07475 GAOABQK02JOCCH CDS478671 2856 + 0.290966
g6756 DLA_07524 GAOABQK02JOCCH CDS588961 2115 - 0.336643
g6857 DLA_07643 GAOABQK02JOCCH CDS812714 6405 - 0.340515
g6866 DLA_07655 GAOABQK02JOCCH CDS839143 2553 + 0.302781
g687 DLA_00758 F4PJNLW01A00V1 CDS111311 2625 + 0.34781
g6883 DLA_07677 GAOABQK02JOCCH CDS880767 1194 + 0.326633
g689 DLA_00761 F4PJNLW01A00V1 CDS118427 1425 + 0.327719
g6929 DLA_11693 GLQOFTK02FH5TG CDS95960 2934 + 0.316633
g6942 DLA_07740 putative protein serinethreonine kinase the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy there is a second copy of this gene GLQOFTK02FH5TG CDS119247 2916 + 0.315844
g6992 DLA_07794 GLQOFTK02FH5TG CDS225458 534 + 0.327715
g7011 DLA_07814 GLQOFTK02FH5TG CDS269937 6186 + 0.35257
g7012 DLA_07815 GLQOFTK02FH5TG CDS276321 2337 - 0.344031
g7015 DLA_07818 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GLQOFTK02FH5TG CDS283213 2583 - 0.342238
g7016 DLA_07821 GLQOFTK02FH5TG CDS291583 3063 + 0.316683
g705 DLA_00778 F4PJNLW01A00V1 CDS153474 432 - 0.298611
g7119 DLA_07947 GLQOFTK02FH5TG CDS533740 2316 + 0.355786
g713 DLA_00785 F4PJNLW01A00V1 CDS167363 1281 + 0.323966
g7217 DLA_08053 GLQOFTK02FH5TG CDS742825 5442 - 0.34932
g7222 DLA_08062 GLQOFTK02FH5TG CDS759231 1590 + 0.284906
g7270 DLA_08116 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationGLQOFTK02FH5TG CDS864074 2313 - 0.378729
g7283 DLA_08133 GLQOFTK02FH5TG CDS894541 1524 + 0.324803
g7309 DLA_08165 similar to the cofilin phosphatase slingshot and to other dual-specificity phosphatasesbr there is a second copy of this gene GLQOFTK02FH5TG CDS948410 1101 + 0.322434
g7357 DLA_08224 STE20PAK protein kinase required for normal chemotaxis contains PAK-boxP21-Rho-binding (CRIB) domain and pleckstrin homology (PH) domainGLQOFTK02FH5TG CDS1063318 1470 + 0.383673
g74 DLA_00085 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene contig05409_1.exp CDS177081 1011 - 0.328388
g7434 DLA_08313 GLQOFTK02FH5TG CDS1251930 1500 - 0.29
g7438 DLA_08319 STE20PAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis contains PAK-boxP21-Rho-binding (CRIB) domain found in the WASP C-terminalGLQOFTK02FH5TG CDS1260149 3315 + 0.355656
g7469 DLA_08356 GLQOFTK02FH5TG CDS1335202 1944 - 0.308128
g7498 DLA_11717 GLQOFTK02FH5TG CDS1403137 438 - 0.276256
g7533 DLA_08427 GLQOFTK02FH5TG CDS1483060 3141 + 0.323464
g754 DLA_00830 similar to mammalian XPR1 which may confer susceptibility to infection with murine leukaemia viruses also similar to yeast SYG1 a G-protein associated signal transduction protein and plant PHO1 that may be involved in phosphate transportF4PJNLW01A00V1 CDS266491 2316 - 0.324698
g7666 DLA_08571 GLQOFTK02G2F2O CDS229400 3729 + 0.335747
g7724 DLA_08642 GLQOFTK02G2F2O CDS383694 4512 - 0.359043
g7748 DLA_08663 GLQOFTK02G2F2O CDS439272 1941 + 0.296754
g7766 DLA_08684 member of the TKL (tyrosine kinase-like) group of protein kinases contains filamin repeat similar to ABP120GLQOFTK02G2F2O CDS482933 4218 + 0.336415
g7784 DLA_08700 putative protein serinethreonine kinase similar to yeast CDC5 Drosophila polo and mammalian PLK which play a role in mitosis and localize to the centrosomesGLQOFTK02G2F2O CDS522616 2478 - 0.315174
g7812 DLA_08732 protein serinethreonine phosphatase required for chemotaxis and development suppresses the GLQOFTK02G2F2O CDS578711 918 - 0.360566
g7892 DLA_08825 GLQOFTK02G2F2O CDS749498 1536 + 0.326172
g7909 DLA_08843 GLQOFTK02G2F2O CDS779995 1656 + 0.300121
g7916 DLA_08851 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene GLQOFTK02G2F2O CDS793088 993 - 0.293051
g7923 DLA_08857 GLQOFTK02G2F2O CDS804563 1752 + 0.304224
g7939 DLA_08873 GLQOFTK02G2F2O CDS845720 2619 - 0.316915
g7953 DLA_08888 GLQOFTK02G2F2O CDS886835 1737 + 0.35118
g8077 DLA_09028 GLQOFTK02G2F2O CDS1171541 1416 + 0.336158
g8099 DLA_09052 GLQOFTK02G2F2O CDS1220399 549 + 0.264117
g8108 DLA_09063 GLQOFTK02G2F2O CDS1245728 2325 - 0.32086
g812 DLA_00892 F4PJNLW01A00V1 CDS372454 2172 + 0.371547
g8123 DLA_09078 GLQOFTK02G2F2O CDS1290791 1539 + 0.345679
g82 DLA_00094 contig05409_1.exp CDS186440 2235 - 0.365101
g8213 DLA_09170 protein serinethreonine kinase GSK family member of the CMGC kinase group essential for cell specification activated by CAR3 through ZAK1 (prespore-) and inhibited by CAR4 (prestalk-) signallingGLQOFTK02G2F2O CDS1477962 1386 - 0.330447
g8218 DLA_09175 GLQOFTK02G2F2O CDS1490003 1221 - 0.329238
g8250 DLA_09212 GLQOFTK02G2F2O CDS1568149 1248 + 0.334135
g8261 DLA_09221 GLQOFTK02G2F2O CDS1591695 1860 + 0.374731
g8280 DLA_09241 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family contains a C2 domain (Ca2-dependent membrane-targeting module) an ankyrin repeat region and a SAM (Sterile alpha motif) domainGLQOFTK02G2F2O CDS1628524 2817 + 0.334398
g8298 DLA_09259 GLQOFTK02G2F2O CDS1673495 3150 + 0.334603
g832 DLA_00912 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW01A00V1 CDS418405 1833 + 0.355701
g835 DLA_00916 F4PJNLW01A00V1 CDS428746 1794 - 0.375697
g8368 DLA_09334 GLQOFTK02G2F2O CDS1804605 483 + 0.337474
g838 DLA_00918 phosphoinositide phosphatase with low specific activity compared to other known phosphoinositide phosphatases can dephosphorylate several phosphoinositide substrates with a preference for PI(5)P constitutively expressed putative ortholog of H. sapiens EPM2A involved in myoclonic epilepsy of LaforaF4PJNLW01A00V1 CDS439027 657 - 0.316591
g8396 DLA_09365 GLQOFTK02G2F2O CDS1852909 447 - 0.317673
g8403 DLA_09372 GLQOFTK02G2F2O CDS1864027 1155 + 0.316883
g8412 DLA_09381 GLQOFTK02G2F2O CDS1880032 2088 - 0.357759
g8420 DLA_09390 the kinase domain is similar to mammalian stress-induced STK and OSR1 (oxidative stress responsive 1) kinases and other STE20-like kinasesbrbr bCommunity annotation:b Fray1 and Fray2 represent the FRAY-subfamily of Ste20-like kinases in D. discoideum (see GLQOFTK02G2F2O CDS1897895 3102 + 0.356222
g8509 DLA_09485 GLQOFTK02GHM7A CDS40990 7914 + 0.321203
g8522 DLA_09499 putative protein serinethreonine kinase similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe)GLQOFTK02GHM7A CDS76238 2130 + 0.302817
g8558 DLA_11779 GLQOFTK02GHM7A CDS154270 270 + 0.277778
g8593 DLA_09585 GLQOFTK02GHM7A CDS246755 4185 + 0.314934
g8597 DLA_09589 GLQOFTK02GHM7A CDS256496 2496 - 0.306891
g8628 DLA_09622 GLQOFTK02GHM7A CDS340924 834 - 0.266187
g8656 DLA_09651 similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases predicted to activate SG2 cyclins cyclin A B and DGLQOFTK02GHM7A CDS398221 876 - 0.381279
g8695 DLA_09691 GLQOFTK02GHM7A CDS481830 1944 - 0.360082
g8717 DLA_09713 contains three EF hands similar to mammalian neuron specific calcium-binding protein hippocalcin belongs to the frequenins a family of myristoyl-switch calcium-binding proteinsGLQOFTK02GHM7A CDS536286 837 - 0.287933
g8754 DLA_09749 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinaseGLQOFTK02GHM7A CDS614852 1455 - 0.364948
g8760 DLA_09756 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activationGLQOFTK02GHM7A CDS625916 2046 - 0.351417
g8778 DLA_09776 GLQOFTK02GHM7A CDS658485 1215 + 0.302058
g8805 DLA_09810 GLQOFTK02GHM7A CDS726834 1869 + 0.316212
g8819 DLA_09821 GLQOFTK02GHM7A CDS774623 1158 - 0.310881
g8847 DLA_09849 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis not a human Nek3 homologGLQOFTK02GHM7A CDS851623 2403 + 0.293383
g8867 DLA_09881 regulatory subunit of the Casup2supcalmodulin-dependent serinethreonine protein phosphatase contains an EF-hand calcium binding motifGLQOFTK02GQ36N CDS15916 540 + 0.274074
g8869 DLA_09883 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases belongs to the PAKL subfamilystress-responsive kinase there is a second copy of this gene GLQOFTK02GQ36N CDS17991 1569 - 0.297642
g8885 DLA_09899 GLQOFTK02GQ36N CDS44251 708 + 0.323446
g8896 DLA_09914 GLQOFTK02GQ36N CDS80933 2232 - 0.336022
g89 DLA_00104 contig05409_1.exp CDS205615 3432 + 0.337121
g8900 DLA_09918 GLQOFTK02GQ36N CDS86387 2031 - 0.293451
g8906 DLA_09925 GLQOFTK02GQ36N CDS97926 1716 - 0.327506
g8907 DLA_09926 similar to mammalian XPR1 which may confer susceptibility to infection with murine leukaemia viruses also similar to yeast SYG1 a G-protein associated signal transduction protein and plant PHO1 that may be involved in phosphate transport GLQOFTK02GQ36N CDS100032 2586 - 0.310905
g8941 DLA_09960 GLQOFTK02GQ36N CDS186083 1941 - 0.325605
g8961 DLA_09982 ortholog of the yeast IRE1 serinethreonine kinaseendoribonuclease a transmembrane protein involved in the unfolded protein response contains a ribonuclease 2-5A domain and 3 pyrrolo-quinoline quinone (PQQ) domainsGLQOFTK02GQ36N CDS225395 3168 - 0.322285
g8975 DLA_09997 GLQOFTK02GQ36N CDS257526 2103 - 0.314788
g9035 DLA_10056 GLQOFTK02GQ36N CDS377200 1983 + 0.33535
g9056 DLA_10077 GLQOFTK02GQ36N CDS417938 447 - 0.288591
g9075 DLA_10099 GLQOFTK02GQ36N CDS469272 1191 - 0.275399
g9098 DLA_10129 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase rasGLQOFTK02GQ36N CDS538065 4770 - 0.341719
g9120 DLA_10154 GLQOFTK02GQ36N CDS597098 552 - 0.298913
g9122 DLA_10157 GLQOFTK02GQ36N CDS599686 3750 - 0.333067
g9152 DLA_10193 protein serinethreonine kinase CK1 family similar to human CK1 and yeast YCK may play a role in DNA repair there is a second copy of this gene GLQOFTK02GQ36N CDS660860 1158 - 0.325561
g9210 DLA_10261 GLQOFTK02GUKFG CDS129499 4644 + 0.343239
g9312 DLA_10379 GLQOFTK02GUKFG CDS381941 1743 + 0.325875
g9327 DLA_10395 GLQOFTK02GUKFG CDS404946 1500 - 0.340667
g9335 DLA_10408 GLQOFTK02GUKFG CDS428539 1335 + 0.310861
g9377 DLA_10448 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteinsbrbr bCommunity annotation:b The five fhk-X genes differ substantially in their response to the disruption of the retinoblastoma-like gene rblA. FhkA is substantially and highly signficantly upregulated in the ko strain while none of the other genes show major changes. Consistent with its regulation the fhkA promoter contains a putative E2F-type binding site (TTTGCGCCTTTT). Virtually all genes associated with replication fork progression are upregulated in the rblA disruptant these include cdc45 all mcm genes all gins genes all rfc genes four polA subunits three polD subunits two putatitive polE subunits PCNA the single-strand binding protein rfa1 the flap endonuclease repG as well as DNA ligase-1 and topoisomerase-2. All these genes show overexpression factors ranging from 4 to 15GLQOFTK02GUKFG CDS509525 1584 - 0.297348
g9445 DLA_10523 GLQOFTK02IIOHN CDS85920 4386 + 0.332421
g945 DLA_01044 F4PJNLW01A00V1 CDS689006 3144 - 0.310433
g9617 DLA_10723 GLQOFTK02IRMR1 CDS31401 4668 - 0.336118
g9624 DLA_10729 GLQOFTK02IRMR1 CDS53933 4098 + 0.340898
g963 DLA_01066 F4PJNLW01A00V1 CDS736130 7947 - 0.317227
g9636 DLA_10743 GLQOFTK02IRMR1 CDS81280 1392 - 0.333333
g9648 DLA_10760 GLQOFTK02IRMR1 CDS111344 1833 - 0.346972
g9657 DLA_10770 GLQOFTK02IRMR1 CDS131584 1497 + 0.334001
g9695 DLA_10819 homolog of S. cerevisiae CDC50 (cell division control protein 50) which is required for polarized cell growth contains two putative transmembrane domainsGLQOFTK02JCFFB CDS13761 924 - 0.32684
g9711 DLA_10837 plays a role in the regulation of cleavage furrow formation similar to S. pombe cdc7GLQOFTK02JCFFB CDS55659 3321 + 0.350196
g9730 DLA_10862 GLQOFTK02JCFFB CDS106430 2298 - 0.295909
g9744 DLA_10878 GLQOFTK02JL55Q CDS18609 327 - 0.33945
g9853 DLA_10997 protein serinethreonine phosphatase required for chemotaxis and development suppresses the GLQOFTK02JL55Q CDS269264 924 - 0.338745
g9859 DLA_11004 GLQOFTK02JL55Q CDS280021 1545 - 0.374757
g986 DLA_01096 F4PJNLW01A00V1 CDS794819 3531 + 0.353724
g987 DLA_11460 F4PJNLW01A00V1 CDS798527 3270 + 0.355352
g9870 DLA_11015 GLQOFTK02JL55Q CDS307354 3702 + 0.337655
g9877 DLA_11025 GLQOFTK02JL55Q CDS327533 1737 + 0.352332
g9897 DLA_11046 GLQOFTK02JL55Q CDS366394 2460 - 0.367886
g9965 DLA_11115 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesisGLQOFTK02JL55Q CDS530149 2103 + 0.32525
g9996 DLA_11151 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family contains RasGEF nucleotide exchange factor domainGLQOFTK02JL55Q CDS582167 2604 + 0.355607