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COG category: Inorganic ion transport and metabolism
Organism: Dictyostelium discoideum AX4, AX4

Number of genes found: 155

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Dictyostelium discoideum AX4, AX4
NameLocus tagProduct / DescriptionGenomic elementTypeBeginLengthStrandGC-content
DDB_G0267698 DDB_G0267698 DDB0232428 CDS623530 372 - 0.284946
DDB_G0267824 DDB_G0267824 DDB0232428 CDS922136 1509 - 0.266402
DDB_G0267924 DDB_G0267924 catalyzes the reaction ATP Hsub2subO Nasupsupn Ksupsupout ADP phosphate Nasupsupout Ksupsupn br contains 10 transmembrane domainsDDB0232428 CDS1128799 3330 + 0.331231
DDB_G0268060 DDB_G0268060 DDB0232428 CDS1380972 2445 - 0.312883
DDB_G0268074 DDB_G0268074 DDB0232428 CDS1408319 2991 - 0.251755
DDB_G0268230 DDB_G0268230 DDB0232428 CDS1727069 1764 + 0.265306
DDB_G0268810 DDB_G0268810 ortholog of bacterial Mgsup2sup transporter mgtA contains eight transmembrane domainsDDB0232428 CDS2146485 2865 + 0.339965
DDB_G0269332 DDB_G0269332 belongs to a family of zinc transporters that are integral membrane proteins which are found to increase tolerance to divalent metal ions contains 6 putative transmembrane domainsDDB0232428 CDS2554441 1845 + 0.280217
DDB_G0269380 DDB_G0269380 P-type ATPase (E1-E2) highly similar to human ATP8A1 believed to be involved in the transport of aminophospholipidsDDB0232428 CDS2645714 3942 - 0.348554
DDB_G0269590 DDB_G0269590 DDB0232428 CDS3078895 4161 - 0.280221
DDB_G0269964 DDB_G0269964 DDB0232428 CDS3938864 1998 + 0.285285
DDB_G0270284 DDB_G0270284 contains an N-terminal DOMON domain as it occurs in dopamine beta-monooxygenases the Dictyostelium protein is followed by a cytochrome b561 domain which contains 5 putative transmembrane regions in addition the protein contains a putative signal peptideDDB0232428 CDS4579488 1173 + 0.277067
DDB_G0270304 DDB_G0270304 DDB0232428 CDS4607306 630 - 0.284127
DDB_G0270720 DDB_G0270720 DDB0232428 CDS4125800 1560 + 0.239744
DDB_G0272192 DDB_G0272192 DDB0232429 CDS1412468 1497 + 0.329993
DDB_G0273083 DDB_G0273083 member of the Dyp-type peroxidase family lacking a typical heme-binding region does not appear to be present in higher organisms there is a second copy of this gene DDB0232429 CDS2623576 921 - 0.334419
DDB_G0273195 DDB_G0273195 member of the major facilitator superfamily (MFS) expressed in upper cup during culmination there is a second copy of this gene DDB0232429 CDS2690707 1764 - 0.294218
DDB_G0273235 DDB_G0273235 contains 8 transmembrane domains there is a second copy of this gene DDB0232429 CDS2765356 3843 - 0.284934
DDB_G0273675 DDB_G0273675 contains eight transmembrane domains there is a second copy of this gene DDB0232429 CDS3262518 3843 + 0.284934
DDB_G0273735 DDB_G0273735 member of the major facilitator superfamily (MFS) expressed in upper cup during culmination there is a second copy of this gene DDB0232429 CDS3339316 1764 + 0.294218
DDB_G0273789 DDB_G0273789 member of the Dyp-type peroxidase family lacking a typical heme-binding region does not appear to be present in higher organisms there is a second copy of this gene DDB0232429 CDS3407290 921 + 0.334419
DDB_G0274547 DDB_G0274547 DDB0232429 CDS4197500 1554 + 0.279923
DDB_G0274643 DDB_G0274643 DDB0232429 CDS4531583 855 + 0.352047
DDB_G0274807 DDB_G0274807 DDB0232429 CDS3946871 1851 - 0.222582
DDB_G0275169 DDB_G0275169 DDB0232429 CDS5084018 3873 + 0.268009
DDB_G0275343 DDB_G0275343 DDB0232429 CDS5393905 1638 - 0.234432
DDB_G0275535 DDB_G0275535 DDB0232429 CDS5868742 3477 + 0.300546
DDB_G0275871 DDB_G0275871 DDB0232429 CDS5796327 3492 - 0.286655
DDB_G0276293 DDB_G0276293 DDB0232429 CDS6559102 1473 - 0.304141
DDB_G0276375 DDB_G0276375 DDB0232429 CDS6671139 3804 - 0.226078
DDB_G0276429 DDB_G0276429 DDB0232429 CDS6932540 1422 - 0.270042
DDB_G0276541 DDB_G0276541 DDB0232429 CDS6819663 5490 - 0.298725
DDB_G0276663 DDB_G0276663 DDB0232429 CDS7094813 2835 - 0.292064
DDB_G0277167 DDB_G0277167 DDB0232429 CDS7668593 1392 + 0.257902
DDB_G0277349 DDB_G0277349 DDB0232429 CDS7803232 759 - 0.310935
DDB_G0278047 DDB_G0278047 DDB0232430 CDS191972 1164 - 0.285223
DDB_G0278059 DDB_G0278059 similar to the human acetyl-coenzyme A transporter 1 contains 10 putative transmembrane domainsDDB0232430 CDS207407 1857 - 0.234787
DDB_G0278265 DDB_G0278265 DDB0232430 CDS581627 1983 + 0.252647
DDB_G0278369 DDB_G0278369 DDB0232430 CDS768975 1170 + 0.22735
DDB_G0278675 DDB_G0278675 DDB0232430 CDS789665 1752 - 0.261986
DDB_G0279275 DDB_G0279275 DDB0232430 CDS1874332 1704 + 0.286385
DDB_G0279943 DDB_G0279943 belongs to the major facilitator superefamily contains 12 putative transmembrane domainsDDB0232430 CDS2721717 1488 - 0.309812
DDB_G0281155 DDB_G0281155 putative sugar transporter contains 12 putative transmembrane domainsDDB0232430 CDS4113808 1614 + 0.29368
DDB_G0281401 DDB_G0281401 DDB0232430 CDS4429232 3771 + 0.307611
DDB_G0281643 DDB_G0281643 DDB0232430 CDS4751182 2787 + 0.22605
DDB_G0282067 DDB_G0282067 belongs to a family of zinc transporters that are integral membrane proteins which are found to increase tolerance to divalent metal ions contains 6 putative transmembrane domainsDDB0232430 CDS5363274 1722 - 0.349013
DDB_G0282285 DDB_G0282285 DDB0232430 CDS5511594 1578 - 0.247148
DDB_G0282311 DDB_G0282311 DDB0232430 CDS5621318 1992 + 0.314759
DDB_G0282945 DDB_G0282945 DDB0232431 CDS31559 2010 - 0.280597
DDB_G0282959 DDB_G0282959 DDB0232431 CDS52235 4611 + 0.25591
DDB_G0283191 DDB_G0283191 DDB0232431 CDS394762 1695 + 0.277286
DDB_G0283629 DDB_G0283629 belongs to a family of zinc transporters that are integral membrane proteins which are found to increase tolerance to divalent metal ions contains 6 putative transmembrane domainsDDB0232431 CDS885727 1632 - 0.321691
DDB_G0283985 DDB_G0283985 DDB0232431 CDS1263489 1608 + 0.250622
DDB_G0284605 DDB_G0284605 conserved plasma membrane calcium ATPases (PMCA) similar to Dictyostelium PAT1 contains 10 predicted transmembrane domainsDDB0232431 CDS2214347 2784 + 0.354526
DDB_G0284849 DDB_G0284849 DDB0232431 CDS2557758 3561 + 0.298512
DDB_G0284955 DDB_G0284955 DDB0232431 CDS2684549 4602 - 0.27488
DDB_G0285079 DDB_G0285079 DDB0232431 CDS2802048 603 + 0.296849
DDB_G0285511 DDB_G0285511 DDB0232431 CDS3331170 1683 - 0.322638
DDB_G0285541 DDB_G0285541 putative family member of integral membrane proteins that are found to increase tolerance to divalent metal ions such as cadmium zinc and cobalt contains 5 predicted transmembrane domainsDDB0232431 CDS3356593 1305 - 0.314176
DDB_G0286043 DDB_G0286043 DDB0232431 CDS3989629 1887 + 0.225755
DDB_G0286611 DDB_G0286611 DDB0232431 CDS4704484 3666 - 0.267321
DDB_G0286639 DDB_G0286639 DDB0232431 CDS4771485 1107 - 0.307136
DDB_G0286727 DDB_G0286727 similar to ChaC proteins thought to be associated with the putative ChaA calciumhydrogen cation transport protein in E. coli but with a PUA RNA binding domain fused at the carboxyl terminusDDB0232431 CDS4900621 969 - 0.330237
DDB_G0286763 DDB_G0286763 DDB0232431 CDS4937865 1977 - 0.195245
DDB_G0286891 DDB_G0286891 DDB0232431 CDS5031762 3546 + 0.227862
DDB_G0286979 DDB_G0286979 DDB0232431 CDS5150412 1884 - 0.277601
DDB_G0287843 DDB_G0287843 DDB0232432 CDS806278 1923 - 0.333853
DDB_G0288055 DDB_G0288055 belongs to a family of conserved potassium transporters in bacteria yeast and plants overexpressed in DDB0232432 CDS929613 2151 - 0.317992
DDB_G0288535 DDB_G0288535 DDB0232432 CDS1660756 1395 - 0.235842
DDB_G0289143 DDB_G0289143 contains 11 putative transmembrane domains similar to D. purpureum proteinDDB0232432 CDS2407681 1719 + 0.285049
DDB_G0289473 DDB_G0289473 ortholog of the conserved plasma membrane calcium ATPases (PMCA) such as Dictyostelium PAT1 contains at least 8 predicted transmembrane domainsDDB0232432 CDS2830601 3234 - 0.310761
DDB_G0289621 DDB_G0289621 DDB0232432 CDS3043521 714 + 0.317927
DDB_G0289703 DDB_G0289703 DDB0232432 CDS3127157 2931 + 0.247015
DDB_G0289985 DDB_G0289985 similar to human protein KIAA0195 a transmembrane protein contains 8 putative transmembrane domainsDDB0232432 CDS3471284 5832 - 0.290123
DDB_G0290423 DDB_G0290423 DDB0232432 CDS4067949 1743 + 0.242111
DDB_G0291029 DDB_G0291029 catalyzes the reaction SOsub4subsup2-sup ATP APS pyrophosphateDDB0232432 CDS4928744 1767 - 0.367289
DDB_G0291141 DDB_G0291141 belongs to a family of zinc transporters that are integral membrane proteins which are found to increase tolerance to divalent metal ions contains 15 putative transmembrane domainsDDB0232432 CDS5043001 2313 + 0.278859
DDB_G0291384 DDB_G0291384 DDB0232433 CDS226725 1878 + 0.256124
DDB_G0291720 DDB_G0291720 DDB0232433 CDS721305 1278 - 0.311424
DDB_G0291722 DDB_G0291722 DDB0232433 CDS719367 1344 - 0.233631
DDB_G0291758 DDB_G0291758 DDB0232433 CDS697440 1194 + 0.273869
DDB_G0291816 DDB_G0291816 DDB0232433 CDS805833 1002 - 0.313373
DDB_G0291824 DDB_G0291824 DDB0232433 CDS827281 1878 - 0.300319
DDB_G0292412 DDB_G0292412 similar to S. cerevisiae and S. pombe TRK1 and TRK2 potassium transporters contains 9 predicted transmembrane domainsDDB0232433 CDS1563103 1947 - 0.260401
DDB_G0292432 DDB_G0292432 DDB0232433 CDS1610862 1815 - 0.293113
alg9 DDB_G0279349 CAZy family GT22 catalyzes N-linked mannosylationDDB0232430 CDS1972184 1950 + 0.232308
alp DDB_G0278495 catalyzes the reaction a phosphate monoester Hsub2subO an alcohol phosphate exhibits a punctate pattern in immunoflourescence that most likely represents vesicles enzymatic activity is developmentally regulated in a cell type-specific mannerDDB0232430 CDS968065 1680 - 0.380952
amtA DDB_G0277503 DDB0232429 CDS8112427 1392 - 0.35704
amtB DDB_G0277889 similar to Arabidopsis AMT1 involved in transporting ammonia in the environment into the cell contains 11 transmembrane domainsDDB0232430 CDS276805 1296 + 0.364198
amtC DDB_G0267424 similar to Arabidopsis AMT1 involved in transporting ammonia in the environment into the cell contains 11 transmembrane domainsDDB0232428 CDS1034624 1296 + 0.350309
arsA DDB_G0293528 homologous to bacterial genes that are involved in the transport of arsenate selenate and other anionic compounds outside the cellDDB0232433 CDS3193289 990 - 0.285859
arsB DDB_G0289879 has two putative transmembrane domains bacterial homolog associates with ArsA to transport arsenate selenate and other anionic compounds outside the cellDDB0232432 CDS3431951 1692 + 0.253546
atox1 DDB_G0284221 DDB0232431 CDS1705613 204 - 0.289216
atp7a DDB_G0284141 DDB0232431 CDS1486936 2958 - 0.315416
atp9b DDB_G0270870 P-type ATPase (E1-E2) ortholog of human ATP9B and yeast NEO1 which is involved in transport from the Golgi to the ERDDB0232428 CDS2777615 3588 + 0.298495
cahA DDB_G0269106 DDB0232428 CDS4712273 831 + 0.34657
catA DDB_G0274595 catalyzes the reaction 2Hsub2subOsub2sub catalase 2Hsub2subO Osub2sub expressed throughout development expression restricted to prestalk cells during post-aggregationbr bNomenclature conflict:b Do not confuse the acrA gene encoding the late development adenylate cyclase ACR with the genetic locus acrA corresponding to the catA catalase that confers resistance to acriflavin (DDB0232429 CDS3823148 1491 + 0.380952
cax1 DDB_G0279301 contains 13 transmembrane domains transports Ca2 or other cations using the gradient of H or Na generated by energy-coupled primary transporters DDB0232430 CDS1901303 2340 + 0.29188
clcA DDB_G0294096 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimers br bNomenclature conflict:b Do not confuse this gene with clc also known as clcA encoding the clathrin light chainDDB0232429 CDS435997 2592 + 0.328318
clcB DDB_G0276865 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimersDDB0232429 CDS7525349 2448 - 0.280637
clcC DDB_G0276229 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimersDDB0232429 CDS6228081 2274 + 0.311785
clcD DDB_G0278639 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimersDDB0232430 CDS535599 3003 - 0.360972
clcE DDB_G0286491 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimersDDB0232431 CDS4560350 2985 + 0.283417
clcF DDB_G0293130 CLC chloride channels are conserved from prokaryotes to mammals where they play broad physiological roles they assemble to form homo-dimersDDB0232433 CDS2574912 2430 + 0.295885
cln3 DDB_G0291157 ortholog of Cln3 responsible for Batten's disease a juvenile neurological disorderDDB0232432 CDS5060161 1266 - 0.313586
comD DDB_G0283345 similar to drug resistance transporters contains 14 transmembrane domainsDDB0232431 CDS539820 3528 + 0.291667
ctaA DDB_G0293004 DDB0232433 CDS2385585 3897 - 0.308442
cutc DDB_G0287539 DDB0232432 CDS396188 843 - 0.269276
fmoA DDB_G0289779 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232432 CDS3265452 1578 - 0.255387
fmoB DDB_G0271660 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232429 CDS685414 1539 - 0.237167
fmoC DDB_G0289605 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232432 CDS3016817 1566 - 0.244572
fmoD DDB_G0289929 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232432 CDS3451742 1683 + 0.250743
fmoE DDB_G0289931 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232432 CDS3453668 1614 + 0.245973
fmoF DDB_G0289927 belongs to the fmo family similar to flavin-containing monooxygenases from a variety of eukaryotes involved in the metabolism of xenobiotic compoundsDDB0232432 CDS3449477 1590 + 0.255346
fmoG DDB_G0289925 DDB0232432 CDS3446671 1611 + 0.248293
fslB DDB_G0270730 similar to the G-protein coupled receptors contains 7 putative transmembrane domains and a potential signal sequenceDDB0232428 CDS4235323 1929 - 0.258683
fxn DDB_G0293246 yeast and human orthologs regulates mitochondrial iron accumulation mutations in human homolog cause Friedrich's ataxiaDDB0232433 CDS2633195 582 - 0.261168
hatA DDB_G0282141 histidine-rich pH-dependent actin binding protein N-terminal myristoylationDDB0232430 CDS5481850 357 + 0.420168
ionA DDB_G0277269 expressed in pstAB cells and in pstA cells and upper cup during culmination transports ions across membranes using ATP hydrolysis for energy contains 8 transmembrane domainsDDB0232429 CDS7864423 3699 + 0.326304
ippA DDB_G0275663 converts 1D-myo-inositol 14-bisphosphate H2O to 1D-myo-inositol 4-phosphate phosphateDDB0232429 CDS5791228 936 + 0.314103
ippB DDB_G0268652 very similar to A. thaliana AHL and SAL1 phosphatases and S. pombe tol1 (halotolerance protein) all related to the S. cerevisiae HAL2 these proteins are 3'-phosphoadenosine-5'-phosphate (PAP) phosphatases that also act as inositol polyphosphate 1-phosphatases.DDB0232428 CDS1844690 999 + 0.274274
kcnma1 DDB_G0269896 ortholog of the human KCNMA1 a potassium channel activated by both membrane depolarization and increase in cytosolic Ca(2) that mediates export of K() defects in the gene cause generalized epilepsy and paroxysmal dyskinesia (GEPD)DDB0232428 CDS3812473 3735 - 0.274431
kil2 DDB_G0279183 DDB0232430 CDS1731085 3477 + 0.33132
mfsd1 DDB_G0289201 ortholog of the human MSFD1 also knon as SMAP-4 (Smooth Muscle cell-Associated Protein 4) contains 10 putative transmembrane domains and an additional potential signal peptideDDB0232432 CDS2461603 1521 - 0.336621
nhe1 DDB_G0275711 required for cell polarity mediates both Ksupsup facilitation of cell motility and KsupsupNasupsup requirement in chemotactic orientation the genetic interaction between aip1 and nhe1 suggest that defective chemotaxis in nhe1- mutants may be determined by loss of cofilin-dependent actin dynamicsDDB0232429 CDS6042281 2025 - 0.281481
nhe2 DDB_G0281877 DDB0232430 CDS5057597 2064 + 0.228682
nhe3 DDB_G0292830 DDB0232433 CDS2111344 2361 - 0.345616
nhe4 DDB_G0290253 DDB0232432 CDS3840207 3027 - 0.327387
noxB DDB_G0287101 homolog of the mammalian flavocytochrome b large subunit gp91phox essential for spore formationDDB0232431 CDS5216605 2097 - 0.244158
noxC DDB_G0291117 homolog of the mammalian flavocytochrome b large subunit gp91phox essential for spore formation contains calcium-binding EF handDDB0232432 CDS5017189 3429 - 0.222514
nramp1 DDB_G0276973 ortholog of the mammalian SLC11a1 transports iron across the phagolysosomal membrane contains 12 transmembrane domainsDDB0232429 CDS7564058 1602 + 0.314607
nramp2 DDB_G0275815 NRAMP family protein similar to bacterial manganese transport protein mntH contains 12 transmembrane domains involved in iron homeostasis and resistance to pathogenic bacteriaDDB0232429 CDS5536603 1890 + 0.292593
patA DDB_G0277861 P-type ATPase that is up-regulated in calcium-adapted cells contains 10 predicted transmembrane domainsDDB0232430 CDS364618 3348 + 0.373059
patB DDB_G0282817 plasma membrane P-type Hsupsup-ATPase that is necessary for survival in acidic environmentsDDB0232430 CDS6309404 3177 + 0.36481
potA DDB_G0282291 DDB0232430 CDS5660926 2934 + 0.273347
ppk1 DDB_G0293524 similar to bacterial PPK (PPK1 family) which synthesizes poly P a polymer of up to hundreds of phosphate residuesDDB0232433 CDS3029753 3162 - 0.328906
redA DDB_G0293904 catalyzes the reaction NADPH n oxidized hemoprotein NADP() n reduced hemoprotein involved in the metabolism of compounds that control Dictyostelium cell differentiationDDB0232433 CDS3580985 1896 - 0.339135
redB DDB_G0269912 catalyzes the reaction NADPH n oxidized hemoprotein NADP() n reduced hemoprotein similar to the H. sapiens POR protein that is defect in adrenal hyperplasia variant type (AHV) a syndrome with disordered steroidogenesisDDB0232428 CDS3848909 2004 - 0.335329
redC DDB_G0287983 similar to the H. sapiens NDOR1 an oxidoreductase that catalyzes the NADP-dependent reduction of cytochrome c and one-electron acceptorsDDB0232432 CDS927535 1902 + 0.244479
rhgA DDB_G0283389 similar to human Rh50 protein a glycoprotein present on the surface of red blood cells contains 10 transmembrane domainsDDB0232431 CDS634252 1584 - 0.33649
rhgB DDB_G0280059 DDB0232430 CDS3188254 1803 + 0.345535
rliA DDB_G0272783 twelve transmembrane domain protein that may act as a transporter repressed after Legionella pneumophila infectionDDB0232429 CDS2172067 1416 + 0.267655
slc4 DDB_G0270422 DDB0232428 CDS4842234 2307 - 0.229736
sod2 DDB_G0271106 ortholog of the human SOD2 the mitochondrial superoxide dismutase belongs to the ironmanganese superoxide dismutase familyDDB0232429 CDS35093 681 + 0.325991
sodA DDB_G0267420 superoxide dismutase of the SOD1 family expressed at constant levels throughout the life cycle and upregulated upon oxidative stress enriched in prespore cellsDDB0232428 CDS338107 462 + 0.391775
sodB DDB_G0283021 DDB0232431 CDS167774 1284 - 0.351246
sodC DDB_G0282993 GPI-anchored plasma membrane superoxide dismutase upregulated upon oxidative stress mutants have defects in cytokinesis chemotaxis and localization of several protein during aggregationDDB0232431 CDS110200 1224 - 0.332516
sodD DDB_G0281493 DDB0232430 CDS4612258 456 - 0.361842
sodE DDB_G0290343 very similar to human SOD1 defects in which cause familial amyotrophic lateral sclerosis (ALS) belongs to the Cu-Zn superoxide dismutase familyDDB0232432 CDS3992463 459 + 0.294118
sodF DDB_G0281461 DDB0232430 CDS4537876 456 + 0.346491
symA DDB_G0292814 DDB0232433 CDS2158906 1371 - 0.33698
zntA DDB_G0268426 ZIP family zinc transporter LZT subfamily member contains 8 transmembrane domains expressed in pstAB cellsDDB0232428 CDS1375259 1524 + 0.256562
zntB DDB_G0286345 ZIP family zinc transporter LZT subfamily member contains 7 transmembrane domains expressed in pstAB cellsDDB0232431 CDS4327628 1119 + 0.314567
zntC DDB_G0286049 ZIP family zinc transporter LZT subfamily member contains 7 transmembrane domains expressed in pstAB cellsDDB0232431 CDS3998261 1206 + 0.333333
zntD DDB_G0269326 ZIP family zinc transporter LZT subfamily member contains 8 transmembrane domains expressed in pstAB cellsDDB0232428 CDS2544681 2052 - 0.273879