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2024-04-28 15:42:03

Gene list

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COG category: Replication, recombination and repair

Number of genes found: 1968

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Dictyostelium discoideum AX4, AX4
NameLocus tagProduct / DescriptionUniProt / TrEMBL protein nameGenomic elementTypeBeginLengthStrandGC-content
DDB_G0267178_RTE DDB_G0267178 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS1890 1398 + 0.395565
DDB_G0267182_RTE DDB_G0267182 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS5505 2265 + 0.39426
DDB_G0267188_RTE DDB_G0267188 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS10033 1971 + 0.392187
DDB_G0267210_RTE DDB_G0267210 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS29137 2907 + 0.396285
DDB_G0267236_RTE DDB_G0267236 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS46105 2265 - 0.394702
DDB_G0267244_RTE DDB_G0267244 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS57242 2172 - 0.39733
DDB_G0267248_RTE DDB_G0267248 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS61559 663 - 0.377074
DDB_G0267258_RTE DDB_G0267258 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS74542 2265 - 0.392053
DDB_G0267294_RTE DDB_G0267294 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS105880 2265 + 0.393377
DDB_G0267326_RTE DDB_G0267326 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS129934 2457 + 0.400488
DDB_G0267342_RTE DDB_G0267342 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232428 CDS145444 2778 + 0.397768
DDB_G0267514 DDB_G0267514 DDB0232428 CDS259066 2751 - 0.28426
DDB_G0267556 DDB_G0267556 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232428 CDS327145 3480 - 0.281034
DDB_G0267566 DDB_G0267566 putative protein serinethreonine kinase contains an ankyrin repeat domain similar to vertebrate Nek kinases which are involved in regulation of mitosis DDB0232428 CDS343868 2535 - 0.244181
DDB_G0267638 DDB_G0267638 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232428 CDS464992 9210 + 0.282953
DDB_G0267686 DDB_G0267686 member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats contains an RGS (Regulator of G protein Signaling) domain DDB0232428 CDS564277 6693 - 0.276109
DDB_G0268052 DDB_G0268052 DDB0232428 CDS1359896 3105 - 0.298873
DDB_G0268078 DDB_G0268078 DDB0232428 CDS1417972 1524 + 0.281496
DDB_G0268212 DDB_G0268212 contains an N-terminal DEADDEAH box helicase a central helicase associated domain (HA2) and a C-terminal domain of unknown function DUF1605 common to DEAD box helicases DDB0232428 CDS1695570 1368 - 0.234649
DDB_G0268218 DDB_G0268218 DDB0232428 CDS1708888 2547 + 0.217903
DDB_G0268236 DDB_G0268236 DDB0232428 CDS1733949 1590 - 0.367296
DDB_G0268430 DDB_G0268430 DDB0232428 CDS1423638 2802 + 0.246253
DDB_G0268486_ps DDB_G0268486 putative pseudogene contains protein kinase domain DDB0232428 CDS498516 2820 - 0.22305
DDB_G0268492 DDB_G0268492 DDB0232428 CDS520101 2007 - 0.247135
DDB_G0268656 DDB_G0268656 highly similar to human ULK (Unc51-like kinase) does not contain the full consensus sequence required for kinase function DDB0232428 CDS1863917 954 - 0.220126
DDB_G0268660 DDB_G0268660 highly similar to neighboring gene DDB0232428 CDS1873355 6945 - 0.257307
DDB_G0268662 DDB_G0268662 highly similar to neighboring gene DDB0232428 CDS1881042 7572 - 0.267697
DDB_G0268876 DDB_G0268876 member of the TKL (tyrosine kinase-like) group of protein kinases contains filamin repeat similar to ABP120 DDB0232428 CDS2297918 4158 - 0.279702
DDB_G0268914 DDB_G0268914 DDB0232428 CDS2371552 13623 - 0.261396
DDB_G0268922 DDB_G0268922 DDB0232428 CDS1846133 3798 - 0.269879
DDB_G0268924 DDB_G0268924 DDB0232428 CDS1866297 5295 - 0.259679
DDB_G0268926_ps DDB_G0268926 putative pseudogene fragment similar to a family of D. discoideum genes including DDB0232428 CDS1872318 456 - 0.27193
DDB_G0269370 DDB_G0269370 very similar to the human 25 kDa cleavage and polyadenylation specificity factor component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3' processing DDB0232428 CDS2630812 603 + 0.288557
DDB_G0269498 DDB_G0269498 DDB0232428 CDS2883107 1053 - 0.212726
DDB_G0269628 DDB_G0269628 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis DDB0232428 CDS3183487 2214 - 0.303975
DDB_G0269986 DDB_G0269986 DDB0232428 CDS3977474 2391 + 0.24634
DDB_G0270146 DDB_G0270146 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis DDB0232428 CDS4304005 1908 - 0.287212
DDB_G0270444 DDB_G0270444 kinase domain similar to mitogen-activated protein kinases does not contain the consensus sequences required for kinase function N-terminus contains WD40 repeats DDB0232428 CDS4890352 4083 + 0.281411
DDB_G0271376 DDB_G0271376 DDB0232429 CDS144988 762 + 0.295276
DDB_G0271402 DDB_G0271402 DDB0232429 CDS241165 2298 + 0.309835
DDB_G0271538 DDB_G0271538 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family expressed in pstO cells DDB0232429 CDS568653 1584 - 0.285985
DDB_G0271550 DDB_G0271550 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases DDB0232429 CDS634463 1179 + 0.267176
DDB_G0271682 DDB_G0271682 member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats contains two kinase domains one of which is predicted to be inactive DDB0232429 CDS792553 3075 + 0.247154
DDB_G0271732 DDB_G0271732 highly similar to mammalian DNA-binding protein SMUBP-2 (IGHMBP2) involved in muscular atrophy and other diseases putative ortholog of S. cerevisiae HCS1 a DNA helicase associated with alpha DNA polymerase DDB0232429 CDS872358 3075 - 0.267967
DDB_G0271962 DDB_G0271962 DDB0232429 CDS1080455 1401 - 0.271235
DDB_G0272082 DDB_G0272082 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232429 CDS1245702 5517 + 0.237992
DDB_G0272092 DDB_G0272092 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family contains a C2 domain (Ca2-dependent membrane-targeting module) an ankyrin repeat region and a SAM (Sterile alpha motif) domain DDB0232429 CDS1251605 2961 - 0.296184
DDB_G0272254 DDB_G0272254 member of the TKL (tyrosine kinase-like) group contains a galactose oxidase central domain and three Kelch motifs DDB0232429 CDS1396081 3996 - 0.264765
DDB_G0272282 DDB_G0272282 member of the AGC kinase group similar to kinase domains of NDR (nuclear Dbf2-related) and MAST (microtubule-associated serinethreonine kinase) DDB0232429 CDS1572926 6309 + 0.272468
DDB_G0272384 DDB_G0272384 E.coli ATP-dependent DNA helicase RecQ is involved in genome maintenance similar to Bloom syndrome protein defects in BLM cause genetic instability including a high level of sister chromatid exchanges associated with a greatly increased predisposition to a wide range of cancers DDB0232429 CDS1405577 2922 + 0.255305
DDB_G0272388 DDB_G0272388 DDB0232429 CDS1417426 2022 - 0.250247
DDB_G0272472 DDB_G0272472 DDB0232429 CDS1736613 4527 + 0.299978
DDB_G0272554_RTE DDB_G0272554 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232429 CDS1837120 2265 + 0.393377
DDB_G0272797 DDB_G0272797 similar to cyclin dependent protein kinases there is a second copy of this gene DDB0232429 CDS2368968 2043 - 0.313754
DDB_G0272877 DDB_G0272877 contains 4 coiled-coil domains there is a second copy of this gene DDB0232429 CDS2317791 1677 + 0.305903
DDB_G0272997 DDB_G0272997 DDB0232429 CDS2081848 3345 - 0.23707
DDB_G0273053 DDB_G0273053 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog there is a second copy of this gene DDB0232429 CDS2288541 4557 - 0.250384
DDB_G0273165 DDB_G0273165 catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5'-phosphate there is a second copy of this gene DDB0232429 CDS2484199 969 - 0.252838
DDB_G0273907 DDB_G0273907 catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5'-phosphate there is a second copy of this gene DDB0232429 CDS3546510 969 + 0.252838
DDB_G0274007 DDB_G0274007 similar to cyclin dependent protein kinases there is a second copy of this gene DDB0232429 CDS3660427 2043 + 0.313754
DDB_G0274049 DDB_G0274049 contains 4 coiled-coil domains there is a second copy of this gene DDB0232429 CDS3712319 1677 - 0.305903
DDB_G0274075 DDB_G0274075 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog there is a second copy of this gene DDB0232429 CDS3738689 4557 + 0.250384
DDB_G0274399 DDB_G0274399 similar to ATP-dependent RNA helicase M NAM7and to putative helicases involved in RNA maturation SEN1 human senataxin imlicated in ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4) also belongs to this family DDB0232429 CDS4681340 2904 + 0.333333
DDB_G0274419 DDB_G0274419 bCommunity annotation:b DDB_G0274419 appears to encode a DNA polymerase with closest affinities to pol I of bacteria (the Kornberg polymerase). This is a low-processivity polymerase thought to function in DNA repair. DDB_G0274419 is only marginally (2x)overexpressed in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted (Doquang et al in preparation). DNA polymerases associated with replication show overexpression factors of 5- to 14-fold in this strain as as do several genes associated with replication-coupled repair while most genes associated with replication-independent repair pathways show overexpression factors of 2 or less. This suggests that DDB_G0274419 acts in replication-uncoupled DNA repair. Harry MacWilliams September 2009 DDB0232429 CDS4627713 3354 - 0.230471
DDB_G0274483 DDB_G0274483 DDB0232429 CDS4423293 4917 - 0.273744
DDB_G0274613 DDB_G0274613 kinase domain similar to mitogen-activated protein kinases does not contain the consensus sequences known to be required for kinase function contains a RING zinc finger domain DDB0232429 CDS4893134 2496 - 0.260417
DDB_G0274777 DDB_G0274777 similar to Dna2 a DNA replication factor required for Okazaki fragment processing and involved in DNA repair pathways DDB0232429 CDS3809416 5517 + 0.240348
DDB_G0274821 DDB_G0274821 DDB0232429 CDS3992986 2565 - 0.181287
DDB_G0274835 DDB_G0274835 DDB0232429 CDS4088247 369 + 0.238482
DDB_G0274847 DDB_G0274847 DDB0232429 CDS4177568 5643 + 0.270069
DDB_G0274901 DDB_G0274901 DDB0232429 CDS4391451 1377 - 0.17284
DDB_G0274965 DDB_G0274965 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232429 CDS4676573 4203 - 0.281704
DDB_G0275057 DDB_G0275057 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases DDB0232429 CDS5089988 1050 + 0.33619
DDB_G0275165 DDB_G0275165 DDB0232429 CDS5143836 2766 - 0.298988
DDB_G0275469 DDB_G0275469 similar to endonuclease V which catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5'-phosphate DDB0232429 CDS6096697 1617 - 0.29128
DDB_G0275509 DDB_G0275509 DDB0232429 CDS6023716 2607 + 0.197929
DDB_G0275539 DDB_G0275539 DDB0232429 CDS5727073 3975 - 0.272453
DDB_G0275633 DDB_G0275633 ortholog of human SKIV2L2 (SuperKIller Viralicitic 2L2) protein and yeast MTR4 a helicase required for mRNA export from the nucleus DDB0232429 CDS5972320 3387 + 0.346324
DDB_G0276045 DDB_G0276045 DDB0232429 CDS6496624 900 + 0.3
DDB_G0276181 DDB_G0276181 member of the TKL (tyrosine kinase-like) group of protein kinases contains a PH (pleckstrin homology) domain DDB0232429 CDS6410071 4668 - 0.262853
DDB_G0276281 DDB_G0276281 DDB0232429 CDS6608304 1032 - 0.223837
DDB_G0276339_ps DDB_G0276339 putative pseudogene similar to DDB0232429 CDS6661296 507 - 0.353057
DDB_G0276461 DDB_G0276461 putative protein serinethreonine kinase similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe) DDB0232429 CDS6904331 2397 - 0.267418
DDB_G0277165 DDB_G0277165 CAMKL family protein kinase the protein kinase domain is similar to those of the CAMKLBRSK subfamily which are named based on brain-specific expression in human and neuronal expression in worm DDB0232429 CDS7893420 2502 - 0.271783
DDB_G0277211 DDB_G0277211 ortholog of human SKIV2L (SuperKIller Viralicitic 2L) protein and yeast SKI2 a helicase required for repressing propagation of dsRNA viruses DDB0232429 CDS7627913 4137 - 0.292966
DDB_G0277327 DDB_G0277327 DDB0232429 CDS7723793 3354 - 0.304114
DDB_G0277449 DDB_G0277449 member of the AGC kinase group similar to kinase domains of SGK (serum and glucocorticoid responsive kinase) AktPKB and RSK (ribosomal S6 kinase) family members DDB0232429 CDS8121319 1371 + 0.300511
DDB_G0277537 DDB_G0277537 subunit of PI4K responsible for the phosphorylation of phosphatidylinositol (PI) to PI4P (ATP 1-phosphatidyl-1D-myo-inositol ADP 1-phosphatidyl-1D-myo-inositol 4-phosphate) the first committed step in the generation of phosphatidylinositol 45-bisphosphate (PIP2) a precursor of the second messenger inositol 145-trisphosphate (InsP3) DDB0232429 CDS7989159 7383 + 0.301233
DDB_G0277539 DDB_G0277539 putative protein tyrosine kinase similar to human wee1 inhibitor of mitosis through phosphorylation of cdc2 DDB0232429 CDS8010617 2997 - 0.248248
DDB_G0277705 DDB_G0277705 DDB0232429 CDS8352571 1524 - 0.229659
DDB_G0277749 DDB_G0277749 DDB0232429 CDS8434187 5040 + 0.242262
DDB_G0278087_ps DDB_G0278087 putative pseudogene containing a partial protein kinase domain and a partial ankyrin repeat DDB0232430 CDS256195 1557 - 0.285806
DDB_G0278221_RTE DDB_G0278221 ORF2 protein fragment of DIRS1 retrotransposon refer to Genbank M11339 for full-length element DDB0232430 CDS495104 504 + 0.367063
DDB_G0278363 DDB_G0278363 DDB0232430 CDS761869 702 + 0.32906
DDB_G0278425 DDB_G0278425 DDB0232430 CDS866714 3273 - 0.276199
DDB_G0278487 DDB_G0278487 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases belongs to the CMGC group of protein kinases DDB0232430 CDS959760 1911 + 0.288854
DDB_G0278509 DDB_G0278509 DDB0232430 CDS984753 3747 + 0.238858
DDB_G0278521 DDB_G0278521 member of the TKL (tyrosine kinase-like) group the MLK (mixed lineage kinase) family and the HH498 subfamily contains an ankyrin repeat DDB0232430 CDS1000912 2727 - 0.226989
DDB_G0278535 DDB_G0278535 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family contains an ankyrin repeat region and a SAM (Sterile alpha motif) domain DDB0232430 CDS1034770 2547 + 0.329407
DDB_G0278665 DDB_G0278665 DDB0232430 CDS753135 3273 - 0.31103
DDB_G0278761 DDB_G0278761 DDB0232430 CDS1131314 5382 + 0.281865
DDB_G0278825 DDB_G0278825 DDB0232430 CDS1248051 2718 + 0.316409
DDB_G0278827 DDB_G0278827 DDB0232430 CDS1252983 5451 - 0.259035
DDB_G0278845 DDB_G0278845 member of the AGC kinase group similar to kinase domains of NDR (nuclear Dbf2-related) family members DDB0232430 CDS1269374 4053 - 0.265976
DDB_G0278901 DDB_G0278901 DDB0232430 CDS1361340 4488 - 0.282308
DDB_G0278909 DDB_G0278909 member of the TKL (tyrosine kinase-like) group and the ARMK (armadillo repeat-containing kinase) family contains an N-terminal LRR and a C-terminal armadillobeta-catenin repeat unlikely to function as a kinase as it does not contain a catalytic aspartate DDB0232430 CDS1376167 5811 + 0.293581
DDB_G0278937 DDB_G0278937 DDB0232430 CDS1214678 2715 + 0.271455
DDB_G0279209 DDB_G0279209 DDB0232430 CDS1761272 399 - 0.265664
DDB_G0279223 DDB_G0279223 contains a nucleic acid binding domain the oligonucleotideoligosaccharide binding motif (OB fold) DDB0232430 CDS1790126 552 + 0.309783
DDB_G0279405 DDB_G0279405 CAMKL family protein kinase the protein kinase domain has similarity to those of calciumcalmodulin-dependent protein kinase kinases (CAMKK) that belong to a proposed calcium-triggered signaling cascade involved in a number of cellular processes DDB0232430 CDS1975813 2088 + 0.290709
DDB_G0279719 DDB_G0279719 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis DDB0232430 CDS2480611 2829 - 0.265111
DDB_G0279831 DDB_G0279831 putative protein serinethreonine kinase CAMK group the protein kinase domain is similar to those of mammalian CAM kinase I DDB0232430 CDS2602496 2787 + 0.267671
DDB_G0280111 DDB_G0280111 putative protein serinethreonine kinase similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe) DDB0232430 CDS2948944 3381 - 0.280982
DDB_G0280131 DDB_G0280131 member of the TKL (tyrosine kinase-like) group and the ARMK (armadillo repeat-containing kinase) family contains armadillobeta-catenin-like repeats unlikely to function as a kinase as it does not contain a catalytic aspartate DDB0232430 CDS2985578 3579 - 0.308187
DDB_G0280133 DDB_G0280133 CAMK family protein kinase protein kinase domain similar to those of mammalian SNF1 like kinases DDB0232430 CDS2991402 4518 + 0.285967
DDB_G0280257 DDB_G0280257 DDB0232430 CDS3173383 1245 + 0.324498
DDB_G0280281 DDB_G0280281 DDB0232430 CDS3200265 1836 + 0.270697
DDB_G0280413 DDB_G0280413 DDB0232430 CDS3319399 3333 + 0.229223
DDB_G0280461 DDB_G0280461 DDB0232430 CDS3391535 1257 - 0.24105
DDB_G0280557 DDB_G0280557 similar to erkA and erkB and other MAP kinases does not contain the consensus sequences required for kinase function DDB0232430 CDS3496721 1383 + 0.237889
DDB_G0280643 DDB_G0280643 similar to many CMGC family members including several MAPKs DDB0232430 CDS3598294 1329 - 0.261851
DDB_G0280717 DDB_G0280717 member of the AGC kinase group similar to the kinase domains of PKC (protein kinase C) and MAST (microtubule-associated serinethreonine kinase) DDB0232430 CDS3670258 1236 - 0.258091
DDB_G0280765 DDB_G0280765 DDB0232430 CDS3715566 2334 + 0.321765
DDB_G0280855 DDB_G0280855 similar to erkA and erkB and other MAP kinases unlikely to function as a kinase as it does not contain a catalytic aspartate DDB0232430 CDS3794487 1179 + 0.25106
DDB_G0280913 DDB_G0280913 DDB0232430 CDS3873660 1587 - 0.245117
DDB_G0281431 DDB_G0281431 DDB0232430 CDS4477171 2763 + 0.26131
DDB_G0281503 DDB_G0281503 DDB0232430 CDS4637514 3360 + 0.285417
DDB_G0281559 DDB_G0281559 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog REMI mutant forms large sori see DDB0232430 CDS4978870 3066 - 0.299739
DDB_G0281745 DDB_G0281745 DDB0232430 CDS4910382 1794 + 0.337793
DDB_G0281845 DDB_G0281845 DDB0232430 CDS5006578 4032 + 0.255208
DDB_G0281925 DDB_G0281925 DDB0232430 CDS5132437 1761 - 0.366269
DDB_G0282115 DDB_G0282115 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232430 CDS5399711 4923 - 0.275848
DDB_G0282299 DDB_G0282299 DDB0232430 CDS5607244 2508 - 0.219298
DDB_G0282429 DDB_G0282429 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases DDB0232430 CDS5758659 939 - 0.312034
DDB_G0282531 DDB_G0282531 ortholog of human Tat DNase 1 (TATDN1) belongs to a large superfamily of metalloenzymes DDB0232430 CDS5890637 975 - 0.259487
DDB_G0282603 DDB_G0282603 DDB0232430 CDS5993046 600 + 0.261667
DDB_G0282679 DDB_G0282679 DDB0232430 CDS6110131 4380 + 0.237671
DDB_G0282851 DDB_G0282851 DDB0232430 CDS6297857 4146 + 0.263869
DDB_G0282895 DDB_G0282895 member of the TKL (tyrosine kinase-like) group contains three N-terminal MORN (Membrane Occupation and Recognition Nexus) repeats DDB0232430 CDS6249781 4905 + 0.262385
DDB_G0282963 DDB_G0282963 member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats DDB0232431 CDS60445 5286 + 0.265796
DDB_G0283065 DDB_G0283065 putative eukaryotic translation initiation factor 2 alpha (eIF2alpha) kinase putative protein serinethreonine kinase related to the GCN2 (general control non-derepressible) family of protein kinases that phosphorylate the alpha subunit of eIF2 DDB0232431 CDS122741 1914 - 0.242424
DDB_G0283189 DDB_G0283189 similar to DNA polymerase epsilon subunit A in yeast and vertebrates thought to be involved in DNA replication DNA repair and cell-cycle checkpoint control in eukaryotes DDB0232431 CDS385928 7143 - 0.297494
DDB_G0283301 DDB_G0283301 DDB0232431 CDS480042 1992 + 0.254016
DDB_G0283337 DDB_G0283337 DDB0232431 CDS491931 3387 - 0.219368
DDB_G0283397 DDB_G0283397 DDB0232431 CDS606939 2757 - 0.283642
DDB_G0283759 DDB_G0283759 DDB0232431 CDS1232305 3240 + 0.274383
DDB_G0283797 DDB_G0283797 DDB0232431 CDS1118346 1470 - 0.267347
DDB_G0283821 DDB_G0283821 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis DDB0232431 CDS1155677 2826 - 0.295824
DDB_G0283927 DDB_G0283927 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis DDB0232431 CDS1307685 1458 - 0.226337
DDB_G0284241 DDB_G0284241 DDB0232431 CDS1733961 1293 + 0.243619
DDB_G0284251 DDB_G0284251 kinase domain similar to those of mitogen-activated protein kinases similar to the STE20 family DDB0232431 CDS1754346 1491 - 0.273642
DDB_G0284507 DDB_G0284507 putative ortholog of Rad51C which is involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks interacts with XRCC3 DDB0232431 CDS2070281 1146 - 0.233857
DDB_G0284649 DDB_G0284649 DDB0232431 CDS2287653 2103 - 0.258678
DDB_G0284661 DDB_G0284661 putative protein serinethreonine kinase CAMK group kinase domain similar to mammalian CAM kinase I DDB0232431 CDS2309177 1446 - 0.304288
DDB_G0284689 DDB_G0284689 DDB0232431 CDS2350414 5040 + 0.22996
DDB_G0284817 DDB_G0284817 DDB0232431 CDS2518687 1641 - 0.311395
DDB_G0284997 DDB_G0284997 DDB0232431 CDS2784039 1125 - 0.315556
DDB_G0285021 DDB_G0285021 belongs to the complex I LYR family similar to human NDUFB9 (NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 9) DDB0232431 CDS2830332 321 - 0.323988
DDB_G0285243 DDB_G0285243 has partial similarity to the S. cerevisiae SEN1 a putative helicase required for RNA polymerase II transcription termination and processing of RNAs DDB0232431 CDS2998910 6210 + 0.295169
DDB_G0285285 DDB_G0285285 DDB0232431 CDS3060850 1323 - 0.253212
DDB_G0285287 DDB_G0285287 putative ortholog of Rad51D which is involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks DDB0232431 CDS3062767 1065 - 0.23662
DDB_G0285437 DDB_G0285437 DDB0232431 CDS3223269 969 + 0.27451
DDB_G0285463 DDB_G0285463 member of the TKL (tyrosine kinase-like) group and the CZAK (C-terminal domain of ZakA) family contains 7 putative transmembrane domains DDB0232431 CDS3259648 2076 - 0.308285
DDB_G0285767 DDB_G0285767 DDB0232431 CDS3448354 4086 + 0.254772
DDB_G0285911 DDB_G0285911 DDB0232431 CDS3814964 3186 + 0.27307
DDB_G0286065 DDB_G0286065 DDB0232431 CDS4016707 1554 + 0.276062
DDB_G0286071 DDB_G0286071 DDB0232431 CDS4026106 339 - 0.233038
DDB_G0286219 DDB_G0286219 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog highly similar to mammalian TBP-associated factor 172 (TAF-172BTAF1) and yeast MOT1 DDB0232431 CDS4198019 6018 + 0.302758
DDB_G0286479 DDB_G0286479 DDB0232431 CDS4506469 3504 - 0.257991
DDB_G0286481 DDB_G0286481 putative protein serinethreonine kinase similar to casein kinase II the alpha chain of a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein DDB0232431 CDS4514745 1818 - 0.264026
DDB_G0286627 DDB_G0286627 putative protein serinethreonine kinase belongs to the STE group the kinase domain is similar to yeast BCK1 a mitogen-activated protein (MAP) kinase kinase kinase DDB0232431 CDS4756048 2016 - 0.251984
DDB_G0286841 DDB_G0286841 member of the AGC kinase group similar to the kinase domains of MAST kinases (Microtubule-Associated SerineThreonine kinase) DDB0232431 CDS4966020 1389 - 0.218143
DDB_G0286883 DDB_G0286883 DDB0232431 CDS5022922 573 - 0.277487
DDB_G0287001 DDB_G0287001 member of the TKL (tyrosine kinase-like) group contains zinc-binding LIM domain DDB0232431 CDS5188585 1953 - 0.28213
DDB_G0287069 DDB_G0287069 DDB0232431 CDS5289970 1167 + 0.264782
DDB_G0287149 DDB_G0287149 similar to mammalian DNA polymerase kappa (POLK) and E. coli dinB a translesion DNA repair polymerase DDB0232431 CDS5382189 1554 - 0.240026
DDB_G0287171 DDB_G0287171 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232431 CDS5429343 5619 + 0.2399
DDB_G0287397 DDB_G0287397 DDB0232432 CDS251848 2013 - 0.273224
DDB_G0287447 DDB_G0287447 ortholog of the bacterial epsilon subunit of DNA polymerase III a multisubunit enzyme responsible for most of the replicative synthesis in bacteria the contain the editing function and is a proofreading 3'-5' exonuclease the Dictyostelium gene is missing approximately 100 amino acids at the carboxyl terminus DDB0232432 CDS185922 1452 + 0.232782
DDB_G0287533 DDB_G0287533 DDB0232432 CDS373625 1149 + 0.260226
DDB_G0288039 DDB_G0288039 DDB0232432 CDS1009340 771 + 0.268482
DDB_G0288073 DDB_G0288073 DDB0232432 CDS1051212 6114 - 0.292607
DDB_G0288147 DDB_G0288147 member of the tyrosine kinase-like (TKL) group similar to plant serinethreonine kinases contains a phorbol esterdiacylglycerol-binding domain DDB0232432 CDS1147360 4044 + 0.271513
DDB_G0288209 DDB_G0288209 ortholog of mitochondrial twinkle protein involved in mitochondrial DNA (mtDNA) metabolism defects in this gene cause progressive external ophthalmoplegia with mitochondrial DNA deletions autosomal dominant type 3 DDB0232432 CDS1246731 2319 + 0.269082
DDB_G0288573 DDB_G0288573 DDB0232432 CDS1700402 684 + 0.276316
DDB_G0288795 DDB_G0288795 putative protein serinethreonine kinase AGC group similar to the kinase domains of mammalian AKTPKB similar to yeast protein kinases GAD8 and SCH9 DDB0232432 CDS1975761 1926 - 0.317757
DDB_G0288947 DDB_G0288947 DDB0232432 CDS2162285 4416 + 0.279212
DDB_G0289033 DDB_G0289033 DDB0232432 CDS2277325 4770 - 0.292243
DDB_G0289503_ps DDB_G0289503 putative pseudogene almost identical to neighboring gene DDB0232432 CDS2868325 5166 - 0.258227
DDB_G0289529 DDB_G0289529 DDB0232432 CDS2862639 5034 - 0.265395
DDB_G0289705 DDB_G0289705 DDB0232432 CDS3136742 6009 + 0.305542
DDB_G0289719 DDB_G0289719 DDB0232432 CDS3159163 4260 + 0.28662
DDB_G0289921 DDB_G0289921 DDB0232432 CDS3426110 3708 + 0.263484
DDB_G0290311 DDB_G0290311 DDB0232432 CDS3942085 1086 - 0.300184
DDB_G0290471 DDB_G0290471 member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats does not contain the consensus sequences required for kinase function DDB0232432 CDS4105828 1059 - 0.234183
DDB_G0290539 DDB_G0290539 DDB0232432 CDS4236850 714 - 0.219888
DDB_G0290621 DDB_G0290621 DDB0232432 CDS4383355 2904 - 0.22865
DDB_G0290689 DDB_G0290689 homolog of E. coli rppH very similar to DDB0232432 CDS4419333 552 - 0.278986
DDB_G0290859 DDB_G0290859 member of the AGC kinase group similar to NDR (nuclear Dbf2-related) and RSK (ribosomal S6 kinase) family members DDB0232432 CDS4688665 1260 + 0.307143
DDB_G0290969 DDB_G0290969 DDB0232432 CDS4808227 1179 - 0.189992
DDB_G0291131 DDB_G0291131 DDB0232432 CDS5027479 2148 + 0.363128
DDB_G0291133 DDB_G0291133 putative protein tyrosine kinase similar to S. pombe wee1 inhibitor of mitosis through phosphorylation of cdc2 DDB0232432 CDS5030354 2337 + 0.26059
DDB_G0291350 DDB_G0291350 putative protein serinethreonine kinase similar to mammalian MPSK (myristoylated and palmitoylated serinethreonine kinase) a kinase involved in transcriptional regulation and protein phosphorylation may be an intermediary in the TGF-beta signaling pathway DDB0232433 CDS162730 1110 - 0.245045
DDB_G0291464 DDB_G0291464 DDB0232433 CDS369674 3414 - 0.289104
DDB_G0291534 DDB_G0291534 DDB0232433 CDS487852 1113 + 0.261456
DDB_G0291664 DDB_G0291664 highly similar to DDB0232433 CDS338918 2880 + 0.291319
DDB_G0291842 DDB_G0291842 putative protein tyrosine kinase similar to S. pombe WEE1 inhibitor of mitosis through phosphorylation of cdc2 DDB0232433 CDS822502 1059 - 0.351275
DDB_G0291872 DDB_G0291872 DDB0232433 CDS855161 2688 + 0.273438
DDB_G0291918 DDB_G0291918 putative protein serinethreonine kinase CAMK group kinase domain is similar to those of mammalian death-associated protein kinases (DAPK) DDB0232433 CDS943654 2010 + 0.287065
DDB_G0292010 DDB_G0292010 DDB0232433 CDS1014321 2334 + 0.288346
DDB_G0292108 DDB_G0292108 DDB0232433 CDS1192584 2490 - 0.278715
DDB_G0292350 DDB_G0292350 DDB0232433 CDS1496951 3675 + 0.270204
DDB_G0292354 DDB_G0292354 putative protein serinethreonine kinase TTBK family similar to casein kinase similar to mammalian tau-tubulin kinase (TTBK) which phosphorylates the microtubule-associated protein tau implicated in Alzheimer's disease DDB0232433 CDS1420214 1488 + 0.30578
DDB_G0292416 DDB_G0292416 DDB0232433 CDS1569201 2793 - 0.257787
DDB_G0292550 DDB_G0292550 DDB0232433 CDS1642791 4194 - 0.223891
DDB_G0292624 DDB_G0292624 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases DDB0232433 CDS1864394 942 + 0.298301
DDB_G0292914 DDB_G0292914 DDB0232433 CDS2269065 723 + 0.262794
DDB_G0293064 DDB_G0293064 DDB0232433 CDS2418202 1722 - 0.334495
DDB_G0293120 DDB_G0293120 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232433 CDS2546935 6618 - 0.294349
DDB_G0293184 DDB_G0293184 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis contains RhoGAP domain found in the Rho family of small G proteins unlikely to function as a kinase as it does not contain a catalytic aspartate DDB0232433 CDS2540484 3561 + 0.281382
DDB_G0293212 DDB_G0293212 DDB0232433 CDS2696303 2541 + 0.275482
DDB_G0293276 DDB_G0293276 member of the AGC kinase group similar to kinase domains of AktPKB and MAST (microtubule-associated serinethreonine kinase) family members DDB0232433 CDS2701490 1551 - 0.246937
DDB_G0293292 DDB_G0293292 putative protein serinethreonine kinase N-terminal kinase domain similar to vertebrate Nek kinases which are involved in regulation of mitosis C-terminal kinase domain weakly similar to ULK (Unc-51-like kinase) DDB0232433 CDS2647324 4116 + 0.234208
DDB_G0293380 DDB_G0293380 bCommunity annotation:b DDB G0293380 contains a conserved domain which is best matched by COG0116 N6 adenine-specific DNA methylase (E-value 5e-14). The similarity to PRK11783 rRNA methyltransferase is lower (9e-11). The blast matches list both putative RNA methylases and putative N6 adenine-specific DNA methylases. Thus although it does not now appear to be possible to assign DDB_G0293380 conclusively to either category the case for a DNA methylase currently looks a bit stronger.br DDB_G0293380 is overexpressed fivefold (p0.008) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most genes with functions necessary for cell cycle progression are overexpressed in this strain and most of the overexpressed genes have identifiable cell cycle functions. A tempting interpretation is that the product of DDB_G0293380 is involved in a DNA methylation pathway which is coupled with DNA replication. Harry MacWilliams December 2009br DDB0232433 CDS2824551 1686 + 0.242586
DDB_G0293582 DDB_G0293582 DDB0232433 CDS3074914 744 + 0.264785
DDB_G0293586 DDB_G0293586 contains one LisH domain contains 3 predicted coiled-coil domains DDB0232433 CDS3081583 6045 - 0.305045
DDB_G0293958 DDB_G0293958 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis DDB0232433 CDS3460612 4779 + 0.208203
DDB_G0295683 DDB_G0295683 DDB0232433 CDS1769740 4770 + 0.291614
DDB_G0295737 DDB_G0295737 DDB0232432 CDS3359151 2817 - 0.29535
DDB_G0302588 DDB_G0302588 DDB0232428 CDS1056562 10701 - 0.305766
H2Bv3 DDB_G0286509 DDB0232431 CDS4575107 465 + 0.393548
abcH3 DDB_G0275697 DDB0232429 CDS5590467 3357 - 0.233244
alkB DDB_G0285575 DDB0232431 CDS3395637 1182 + 0.307953
apeA DDB_G0277701 AP-endonuclease catalyses the exonucleolytic cleavage of damaged double stranded DNA in the 3'- to 5'-direction to yield nucleoside 5'-phosphates DDB0232429 CDS8367690 1086 + 0.323204
apnA DDB_G0279923 breaks the C-O-P bond 5' to an apurinic or apyrimidinic site in DNA brbr bCommunity annotation:b ApnA has a canonical PCNA-interacting domain also known as a PIP sequence in this case QtsItdFF. For a discussion of PIP domains (see Supplementary table 1 in DDB0232430 CDS2784977 1629 - 0.259055
apnB DDB_G0277247 breaks the C-O-P bond 3' to an apurinic or apyrimidinic site in DNA DDB0232429 CDS7816486 1050 + 0.281905
aqr DDB_G0274797 ortholog of the mammalian aquarius (AQR) protein an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis DDB0232429 CDS3881369 4464 - 0.225134
arkA DDB_G0289555 suppressor of spalten (spnA) mutant member of the TKL (tyrosine kinase-like) group and ARK (ankyrin repeat-containing kinase) family DDB0232432 CDS2941850 4383 + 0.300707
atg1 DDB_G0292390 Dictyostelium homolog of yeast atg1 belongs to the ULK (Unc-51-like kinase) family of kinases required for macroautophagy DDB0232433 CDS1694801 2007 + 0.255605
atr1 DDB_G0291380 atypical PIKK family protein kinase similar to protein kinase ATR which modulates cell cycle progression and DNA repair in other organisms ATR phosphorylates Rad17 histone H2AX p53 and Nbs1 DDB0232433 CDS214264 9474 - 0.259552
aurK DDB_G0279343 putative protein serinethreonine kinase Aur family associates with the mitotic spindle and plays a key role in mitosis the single Dictyostelium aurora kinase has properties of both aurora A and B kinases in other organisms DDB0232430 CDS1959552 1155 - 0.30303
blm DDB_G0292130 E. coli ATP-dependent DNA helicase RecQ is involved in genome maintenance this is the ortholog of the H. sapiens Bloom syndrome protein defects in BLM cause genetic instability including a high level of sister chromatid exchanges associated with a greatly increased predisposition to a wide range of cancers DDB0232433 CDS1240457 3780 + 0.286243
bzpJ DDB_G0274993 DDB0232429 CDS4824947 2364 + 0.258883
cak1-1 DDB_G0273059 protein serinethreonine kinase CK1 family similar to human CK1 and yeast YCK may play a role in DNA repair there is a second copy of this gene DDB0232429 CDS2688821 1281 + 0.320062
cak1-2 DDB_G0273737 protein serinethreonine kinase CK1 family similar to human CK1 and yeast YCK may play a role in DNA repair there is a second copy of this gene DDB0232429 CDS3341355 1281 - 0.320062
casK DDB_G0276885 CK2 family protein kinase a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein DDB0232429 CDS7370887 1014 + 0.310651
cdc6 DDB_G0275983 bCommunity annotation:b ortholog of cdc6 long known to be a critical member of the DNA pre-replication complex and more recently implicated in control of mitosis (see DDB0232429 CDS6146641 1317 + 0.247532
cdc7 DDB_G0292152 similar to S. cerevisiae cell division control protein 7 (CDC7) a serinethreonine kinase required for mitosis and meiosis DDB0232433 CDS1294776 3186 + 0.23666
cdk1 DDB_G0272813 similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases predicted to activate SG2 cyclins cyclin A B and D DDB0232429 CDS2216835 891 + 0.331089
cdk10 DDB_G0268480 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases DDB0232428 CDS294048 1101 - 0.256131
cdk11 DDB_G0283279 very similar to human CDL1 (PITSLRE serinethreonine-protein kinase CDC2L1) which appears to play multiple roles in cell cycle progression cytokinesis and apoptosis predicted to interact with DDB0232431 CDS446640 1077 - 0.338904
cdk5 DDB_G0288677 CMGC group protein kinase highly similar to mammalian cdk5 localizes to the nucleus and shuttles to the cytoplasm during late mitosis binds calmodulin PsaA DDB0232432 CDS1885785 879 + 0.302617
cdk7 DDB_G0285417 putative ortholog of CDK7 and CTK1 which phosphorylates the C-terminal repeated domain of the RNA polymerase II large subunit predicted to be activated by DDB0232431 CDS3627427 1083 + 0.307479
cdk8 DDB_G0267442 controls RNA polymerase II activity by phosphorylating the carboxy terminal domain (CTD) of the largest subunit predicted to interact with DDB0232428 CDS1582311 1143 - 0.314961
cdk9-1 DDB_G0273207 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene DDB0232429 CDS2708039 2085 + 0.282974
cdk9-2 DDB_G0273721 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene DDB0232429 CDS3321422 2085 - 0.282974
cepK DDB_G0293544 localizes to the corona of the centrosome and to centromeres affects cell growth and chemotactic motility and is involved in the interaction with the nuclear envelope DDB0232433 CDS2990987 6333 - 0.225959
chdA DDB_G0284171 CHD gene family protein containing a chromodomain a helicase domain and a DNA-binding domain similar to H. sapiens chromodomain-helicase-DNA-binding protein 2 (CHD-2) (SwissProt: O14647) chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232431 CDS1645755 5754 - 0.310219
chdB DDB_G0280705 CHD gene family protein containing a chromodomain a C terminal helicase domain and a DNA-binding domain chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232430 CDS3648861 7122 - 0.267762
chdC DDB_G0293012 CHD gene family protein containing a chromodomain a helicase domain and a DNA-binding domain chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232433 CDS2321154 9216 + 0.312174
chtf18 DDB_G0272758 in S. cerevisiae essential for the fidelity of chromosome transmission and component of the RFC complexbrbr bCommunity annotation:b CTF18 ( DDB0232429 CDS2108163 2814 + 0.264748
clkA DDB_G0281179 similar to cyclin-like kinases (CLK) putative dual specifity kinase DDB0232430 CDS4167312 2799 + 0.215077
cog4 DDB_G0267960 highly similar to COG4 component of the conserved oligomeric Golgi complex which is composed of eight different subunits DDB0232428 CDS1187972 2736 - 0.240863
commd1 DDB_G0292074 belongs to a family of conserved mammalian HCaRG (hypertension-related calcium-regulated gene) proteins DDB0232433 CDS1155156 564 - 0.210993
cycC DDB_G0274139 similar to metazoan cyclin C predicted to interact with cyclin-dependent kinase DDB0232429 CDS4921649 768 + 0.247396
cycH DDB_G0268668 similar to metazoan cyclin H predicted to interact with cyclin-dependent kinase DDB0232428 CDS1891354 861 - 0.190476
cycK DDB_G0286617 similar to metazoan cyclin K predicted to interact with the cyclin-dependent kinase DDB0232431 CDS4722525 1218 - 0.297209
cycL DDB_G0285553 similar to metazoan and higher plants cyclin Lania-6 predicted to interact with DDB0232431 CDS3372094 822 - 0.284672
dcp2 DDB_G0283315 ortholog of the conserved mRNA-decapping enzyme 2 necessary for the degradation of mRNAs DDB0232431 CDS515744 1863 + 0.31723
dcp2_ps DDB_G0283809 putative pseudogene similar to DDB0232431 CDS1130346 258 - 0.325581
ddx1 DDB_G0269966 ortholog of ATP-dependent RNA helicase DDX1 contains an SPRY domain which is of unknown function DDB0232428 CDS3941617 2298 + 0.302002
ddx10 DDB_G0284017 DDB0232431 CDS1436851 2637 + 0.277209
ddx17 DDB_G0293168 conserved RNA helicase very similar to mammalian DDX17 (p72) and DDX5 (p68) and yeast DBP2 DDB0232433 CDS2360817 2358 - 0.370229
ddx18 DDB_G0282741 DDB0232430 CDS6230156 1809 - 0.334439
ddx20 DDB_G0277527 ortholog of H. sapiens DDX20Gemin 3 a component of Cajal bodies (CBs) and Gems nuclear organelles responsible for spliceosomal small nuclear ribonucleoprotein (snRNP) biogenesis DDB0232429 CDS8128317 2550 - 0.22902
ddx24 DDB_G0281841 DDB0232430 CDS5000989 2823 + 0.30039
ddx27 DDB_G0281711 DDB0232430 CDS4866495 2352 + 0.305697
ddx3 DDB_G0283661 conserved RNA helicase very similar to mammalian DDX3X and DDX3Y and yeast DBP1 DDB0232431 CDS939305 2139 - 0.370266
ddx31 DDB_G0271708 DDB0232429 CDS830367 2727 + 0.26696
ddx41 DDB_G0287361 conserved RNA helicase ortholog of D. melanogaster DEAD box protein abstrakt which is required during post-transcriptional gene expression DDB0232432 CDS183547 2016 - 0.315476
ddx42 DDB_G0288501 conserved putative RNA helicase very similar to mammalian DDX42 DDB0232432 CDS1607944 2961 + 0.274232
ddx47 DDB_G0280147 DDB0232430 CDS3015956 1641 - 0.312614
ddx49 DDB_G0270396 DDB0232428 CDS4752654 1527 + 0.27112
ddx5 DDB_G0293036 DDB0232433 CDS2373448 2094 + 0.258835
ddx51 DDB_G0293740 DDB0232433 CDS3249527 1692 - 0.229905
ddx52 DDB_G0274325 ortholog of H. sapiens DDX52 and S. cerevisiae ROK1 (Rescuer Of Kem1) ROK1 required for 18S rRNA synthesis DDB0232429 CDS3957548 2007 + 0.271051
ddx55 DDB_G0291588 ortholog of H. sapiens DDX55 and S. cerevisiae SBP4 (Suppressor of PAB1) SBP4 required for synthesis of 60S ribosomal subunits DDB0232433 CDS577637 1992 - 0.270582
ddx56 DDB_G0280407 ortholog of H. sapiens DDX56 and S. cerevisiae DBP9 (Dead Box Protein 9) involved in biogenesis of the 60S ribosomal subunit DDB0232430 CDS3312082 2058 + 0.266764
ddx6 DDB_G0291804 ortholog of H. sapiens DDX6 and S. cerevisiae DHH1 (DExDH-box Helicase) DDB0232433 CDS773358 1272 + 0.367925
dhx15 DDB_G0285213 DDB0232431 CDS2984261 2184 + 0.330128
dhx16 DDB_G0285937 DEADDEAH box helicases are involved in various aspects of RNA metabolism including nuclear pre-mRNA splicing DDB0232431 CDS3866187 3321 + 0.311352
dhx33 DDB_G0270110 DEADDEAH box helicases are involved in various aspects of RNA metabolism DDB0232428 CDS4244035 2193 + 0.272686
dhx35 DDB_G0269306 DEADDEAH box helicases are involved in various aspects of RNA metabolism DDB0232428 CDS2485989 2151 - 0.272431
dhx37 DDB_G0287351 ortholog of H. sapiens DHX37 and S. cerevisiae ECM16 an RNA helicase involved in ribosomal biosynthesis DDB0232432 CDS165026 4386 - 0.287278
dhx57 DDB_G0267516 putative RNA helicase contains an RWD domain (RING finger and WD repeat) DDB0232428 CDS263217 4356 - 0.278007
dhx8 DDB_G0291183 conserved RNA helicase S. cerevisiae ortholog PRP22 mediates ATP-dependent mRNA release from the spliceosome and unwinds RNA duplexes DDB0232432 CDS5107365 3483 - 0.335343
dhx9 DDB_G0275313 ortholog of the human DHX9 that unwinds double-stranded DNA and RNA in a 3' to 5' direction DDB0232429 CDS5331812 4419 - 0.27857
dnapkcs DDB_G0281167 atypical PIKK family protein kinase similar to human DNA-PKcs required for the repair of DNA double-strand breaks belongs to the PIKK family of protein kinases DDB0232430 CDS4132807 12900 + 0.265504
dnmA DDB_G0288047 methylates cytosines in DNA belongs to the dnmt2 subfamily which has weak methylase activity DDB0232432 CDS1026957 1140 - 0.240351
drkA DDB_G0289791 DDB0232432 CDS3144874 1929 + 0.276827
drkB DDB_G0289709 DDB0232432 CDS3147575 2073 + 0.2904
drkC DDB_G0281899 tyrosine kinase member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily involved in phagocytosis and late phagosomelysosome fusion enriched in S cells in slugs DDB0232430 CDS5088116 2250 - 0.305778
drkD DDB_G0281557 member of the TKL (tyrosine kinase-like) group and the DRK (Dictyostelium receptor-like kinase) subfamily contains a leucine-rich repeat (LRR) region DDB0232430 CDS4777368 3867 + 0.334885
dst1 DDB_G0274593 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232429 CDS3862026 2214 + 0.289521
dst2 DDB_G0267730 putative protein serinethreonine kinase the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases stress-responsive kinase DDB0232428 CDS719427 3429 + 0.33275
dst3 DDB_G0291267 putative protein serinethreonine kinase the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232433 CDS35064 1689 - 0.351095
dst4 DDB_G0288071 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232432 CDS1048762 1458 - 0.325789
dupA DDB_G0277071 contains both a kinase domain and a phosphatase domain similar to MAP kinase phosphatase in plants and dual-specificty phosphatase 19 in mammals regulates the MAP Kinase response to Legionella pneumophila infection in Dictyostelium DDB0232429 CDS7439874 7365 - 0.295995
dynB DDB_G0285503 DDB0232431 CDS3322100 1293 + 0.269142
dynC DDB_G0277561 DDB0232429 CDS8131744 714 - 0.246499
dyrk1 DDB_G0277485 DDB0232429 CDS7981156 2511 + 0.249303
dyrk2 DDB_G0293750 DDB0232433 CDS3272270 2748 + 0.306405
enlA DDB_G0276103 N-terminal similarity to talin C-terminal similarity to fimbrins actin binding protein plays a role in cytokinesis and substrate adhesionbr bNomenclature conflict:b This gene has been erroneously referred to as DDB0232429 CDS6301145 4512 + 0.341534
ercc1 DDB_G0267682 ortholog of H. sapiens ERCC1 and S. cerevisiae RAD10 nucleotide excision repair genes defects in ERCC1 cause cerebro-oculo-facio-skeletal syndrome type 4 (COFS4) DDB0232428 CDS559492 1545 + 0.291909
ercc6 DDB_G0281441 ortholog of S. cerevisiae RAD26 and H. sapiens ERCC6 (CSB) involved in Cockayne syndrome chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232430 CDS4502255 4968 - 0.273752
erkA DDB_G0286353 DDB0232431 CDS4355028 1590 + 0.303774
erkB DDB_G0283903 DDB0232431 CDS1385123 1110 - 0.323423
exo1 DDB_G0291570 highly similar to S. pombe exonuclease I a 5'-3' exonuclease involved in DNA repair recombination replication and telomere integrity DDB0232433 CDS561048 3141 + 0.266794
exoc7 DDB_G0272991 subunit of the exocyst complex which targets secretory vesicles to active sites of exocytosis DDB0232429 CDS2034015 2523 - 0.328973
fhkA DDB_G0293656 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteinsbrbr bCommunity annotation:b The five fhk-X genes differ substantially in their response to the disruption of the retinoblastoma-like gene rblA. FhkA is substantially and highly signficantly upregulated in the ko strain while none of the other genes show major changes. Consistent with its regulation the fhkA promoter contains a putative E2F-type binding site (TTTGCGCCTTTT). Virtually all genes associated with replication fork progression are upregulated in the rblA disruptant these include cdc45 all mcm genes all gins genes all rfc genes four polA subunits three polD subunits two putatitive polE subunits PCNA the single-strand binding protein rfa1 the flap endonuclease repG as well as DNA ligase-1 and topoisomerase-2. All these genes show overexpression factors ranging from 4 to 15 DDB0232433 CDS3219230 1782 - 0.231201
fhkB DDB_G0280599 CAMK group RAD53 family protein kinase the protein kinase domain is similar to those of mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteins DDB0232430 CDS3548058 3429 - 0.26305
fhkC DDB_G0281567 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 and yeast RAD53 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteins DDB0232430 CDS4871788 1788 + 0.291387
fhkD DDB_G0285963 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteins DDB0232431 CDS3876403 2250 - 0.286667
fhkE DDB_G0280321 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteins DDB0232430 CDS3257414 2139 + 0.257597
fncJ DDB_G0286621 ortholog of Fanconi anaemia complementation group protein involved DNA cross-link repair also known as BRIP1 (BRCA1 Interacting Protein 1) however the Dicty gene appears to be missing the region that interacts with BRCA1 in the human protein unlike other members of the complex null mutant is not sensitive to DNA damaging agents brbr mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A B C E F G L and M the FA complex interacts with ube2t a E2 ubiquitin-conjugating enzyme to monoubiquitinate FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the FANCJ helicase as well as FANCN and FANCD1 in human mutations in this gene cause Fanconi anaemia an autosomal recessive disorder affecting all bone marrow elements Dictyostelium has orthologs for DDB0232431 CDS4729555 3237 + 0.296262
fncM DDB_G0274841 ortholog of Fanconi anaemia complementation group M protein involved DNA cross-link repair null mutant is sensitive to DNA damaging agents brbr mammalian ortholog is part of the Fanconi anaemia nuclear complex that includes FANC A B C E F G L and M the FA complex interacts with ube2t a E2 ubiquitin-conjugating enzyme to monoubiquitinate FANCD2 and FANCI. Ubiquinated FANCD2 and FANCI form a complex that colocalizes at sites of DNA damage with the FANCJ helicase as well as FANCN and FANCD1 in human mutations in this gene cause Fanconi anaemia an autosomal recessive disorder affecting all bone marrow elements Dictyostelium has orthologs for DDB0232429 CDS4112099 5370 + 0.280447
fnkA DDB_G0275561 protein kinase STE group DDB0232429 CDS5624593 2382 + 0.283375
fnkB DDB_G0267934 DDB0232428 CDS1147906 1593 - 0.251726
fnkE DDB_G0275879 protein kinase domain similar to those of the mitogen-activated protein kinases which belong to the STE20 family contains two protein kinase domains one of which is predicted to be inactive contains several FNIP repeats DDB0232429 CDS5838829 3966 + 0.2824
fnkF_ps DDB_G0275183 putative pseudogene STEFNIP protein kinase family DDB0232429 CDS5290527 2628 - 0.270548
fray1 DDB_G0278863 kinase domain similar to OSR1 (oxidative stress responsive 1) kinases and other STE20-like kinasesbrbr bCommunity annotation:b Fray1 and Fray2 represent the FRAY-subfamily of Ste20-like kinases in D. discoideum (see DDB0232430 CDS1298188 1725 - 0.338551
fray2 DDB_G0276577 the kinase domain is similar to mammalian stress-induced STK and OSR1 (oxidative stress responsive 1) kinases and other STE20-like kinasesbrbr bCommunity annotation:b Fray1 and Fray2 represent the FRAY-subfamily of Ste20-like kinases in D. discoideum (see DDB0232429 CDS6994954 3087 - 0.339164
gacJJ DDB_G0290873 DDB0232432 CDS4700102 2622 + 0.300153
gacP DDB_G0279009 DDB0232430 CDS1510645 1731 + 0.317158
gbpC DDB_G0291079 member of the TKL (tyrosine kinase-like) group and ROCO family of protein kinases belongs to the LRRK family of protein kinases contains LRR Roc COR RasGEF protein kinase DEP cyclic nucleotide-binding and GRAM domains involved in cGMP-mediated chemotaxis catalyzes GDP to GTP exchange on its own Roc domain translocates from cytoplasm to cell cortex after cAMP stimulation GRAM domain binds directly to plasma membrane DDB0232432 CDS4959991 7896 + 0.333967
gdt2 DDB_G0270666 member of the TKL (tyrosine kinase-like) group and the GDT family putative transmembrane protein DDB0232428 CDS3713353 4914 - 0.252747
gdt3_ps DDB_G0285891 putative pseudogene member of the TKL (tyrosine kinase-like) group and the GDT family belongs to the MLK protein kinase family DDB0232431 CDS3781232 5880 - 0.234014
gdt4 DDB_G0270550 member of the TKL (tyrosine kinase-like) group and the GDT family putative transmembrane protein DDB0232428 CDS2926042 4863 + 0.265474
gdt6 DDB_G0270544 member of the TKL (tyrosine kinase-like) group and the GDT family unlikely to function as a kinase as it does not contain a catalytic aspartate putative transmembrane protein DDB0232428 CDS2913781 4359 + 0.274145
gdt8 DDB_G0270668 member of the TKL (tyrosine kinase-like) group and the GDT family putative transmembrane protein DDB0232428 CDS3723386 3981 - 0.283848
gdt9 DDB_G0278879 DDB0232430 CDS1327589 4734 + 0.274398
gefX DDB_G0269298 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family contains RasGEF nucleotide exchange factor domain DDB0232428 CDS2476607 2883 - 0.312522
glkA DDB_G0270218 putative protein serinethreonine kinase GSK family member of the CMGC kinase group similar to Drosophila shaggy and other glycogen synthase kinases DDB0232428 CDS4429657 1422 + 0.23699
gskA DDB_G0272110 protein serinethreonine kinase GSK family member of the CMGC kinase group essential for cell specification activated by CAR3 through ZAK1 (prespore-) and inhibited by CAR4 (prestalk-) signalling DDB0232429 CDS1334436 1404 - 0.324786
gtf2h2 DDB_G0272362 DDB0232429 CDS1296713 1386 - 0.309524
gtf2h3 DDB_G0275517 DDB0232429 CDS6059895 1119 + 0.268097
gtf2h4 DDB_G0293228 ortholog of S. cerevisiae TFB2 subunit of TFIIH and nucleotide excision repair factor 3 complexes involved in transcription initiation required for nucleotide excision repair DDB0232433 CDS2676500 1452 - 0.303719
helA DDB_G0292992 DDB0232433 CDS2367392 3276 + 0.291209
helB1 DDB_G0275443 conserved RNA helicase S. cerevisiae ortholog PRP5 is necessary for pre-spliceosome formation DDB0232429 CDS5780689 3456 - 0.335938
helB2 DDB_G0277857 conserved RNA helicase S. cerevisiae ortholog PRP28 is involved in RNA isomerization at the 5' splice site DDB0232430 CDS776296 2505 + 0.335729
helC DDB_G0281553 DDB0232430 CDS4949807 1398 + 0.286838
helE DDB_G0281949 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232430 CDS5309986 4623 - 0.237508
helF DDB_G0294407 DDB0232429 CDS2123898 2514 - 0.28043
ifdA DDB_G0269146 similar to eukaryotic translation initiation factor 4A isoform 2 DDB0232428 CDS2640023 1188 + 0.393939
iksA DDB_G0283109 similar to fungal kinases contains an IQ calmodulin-binding region DDB0232431 CDS257953 2940 + 0.272449
iliI DDB_G0269630 belongs to a superfamily of metalloenzymes induced by Legionella pneumophila infection DDB0232428 CDS3187028 1047 - 0.299904
iliK DDB_G0278649 belongs to a superfamily of metalloenzymes induced by Legionella pneumophila infection DDB0232430 CDS636762 1002 + 0.336327
ino80 DDB_G0292358 similar to S. cerevisiae INO80 an ATPase that forms a large complex containing actin and several actin-related proteins that has chromatin remodeling activity and 3' to 5' DNA helicase activity in vitro chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232433 CDS1406177 6390 + 0.308607
ireA DDB_G0267650 ortholog of the yeast IRE1 serinethreonine kinaseendoribonuclease a transmembrane protein involved in the unfolded protein response contains a ribonuclease 2-5A domain and 3 pyrrolo-quinoline quinone (PQQ) domains DDB0232428 CDS495110 2955 + 0.237902
irlA DDB_G0272987 DDB0232429 CDS2020830 4296 + 0.26513
irlB-1 DDB_G0273333 putative protein serinethreonine kinase the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy there is a second copy of this gene DDB0232429 CDS2539802 4347 - 0.216931
irlB-2 DDB_G0273857 putative protein serinethreonine kinase the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy there is a second copy of this gene DDB0232429 CDS3487559 4347 + 0.216931
irlC DDB_G0270894 the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy contains a SWIM Zn-finger domain DDB0232428 CDS3195968 4335 + 0.231834
irlD DDB_G0269632 DDB0232428 CDS3190841 4518 + 0.261399
irlE DDB_G0288803 putative protein serinethreonine kinase the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy DDB0232432 CDS1985593 4053 + 0.237602
isw DDB_G0292948 similar to ISWI and mammalian SMARCA ATPases involved in nucleosome remodeling chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232433 CDS2254360 3666 + 0.336061
kinX DDB_G0283391 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family similar to LIM kinases which regulate actin dynamics DDB0232431 CDS749416 3285 + 0.312329
kinY DDB_G0289661 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family similar to LIM kinases which regulate actin dynamics DDB0232432 CDS3255902 1740 + 0.251149
krsA DDB_G0284181 putative protein serinethreonine kinase belongs to the protein kinase MST subfamily similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase involved in signal transduction and hyperosmotic response DDB0232431 CDS1697612 1386 - 0.313853
krsB DDB_G0267978 putative protein serinethreonine kinase N-terminus similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase C-terminal half belongs to the peptidase C2 family contains 4 calpain III domains and has similarity to calpain-like cysteine protease DDB0232428 CDS1220851 3318 + 0.331826
kxcA DDB_G0289859 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family contains calmodulin-binding RhoGEF and pleckstrin homology (PH) domains DDB0232432 CDS3309104 3936 + 0.256352
kxcB DDB_G0293124 kinase domain similar to those of stress-induced STK kinases contains a DH (Dbl homology) domain followed by a PH (pleckstrin homology) domain found in proteins shown to encode a GEF activity specific for Rho family members DDB0232433 CDS2557594 3378 - 0.301066
lig1 DDB_G0274493 ATP-dependent DNA ligase required for the ligation of Okazaki fragments during lagging-strand DNA synthesis DDB0232429 CDS4400712 3579 - 0.299246
lig3 DDB_G0283857 ATP-dependent DNA ligase contains the BRCT domain which is also found in BRCA1 interacts with XRCC1 DDB0232431 CDS1062604 3528 + 0.289399
lig4 DDB_G0292760 ATP-dependent DNA ligase contains the BRCT domain which is also found in BRCA1 forms a complex with XRCC4 DDB0232433 CDS2052081 3267 + 0.270279
lkb1 DDB_G0279629 CAMK group CAMKL family kinase protein kinase involved in regulating both development and the stress response DDB0232430 CDS2335074 1761 - 0.294719
lysA DDB_G0276797 contains lysin motifLysM domain may be involved in bacterial cell wall degradation DDB0232429 CDS7337818 4218 - 0.276671
lzic DDB_G0288823 DDB0232432 CDS2035104 579 + 0.26943
magA DDB_G0271050 hydrolyses alkylated adenine residues on DNA releasing 3-methyladenine DDB0232428 CDS4479608 873 - 0.279496
mcm2 DDB_G0286623 similar to MCM2 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232431 CDS4745862 3027 + 0.320449
mcm3 DDB_G0280309 similar to MCM3 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232430 CDS3235987 2604 - 0.305684
mcm4 DDB_G0275623 similar to MCM4 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232429 CDS5936245 2661 - 0.287862
mcm5 DDB_G0292958 similar to MCM5 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232433 CDS2121500 2274 - 0.329815
mcm6 DDB_G0272760 similar to MCM6 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232429 CDS2111171 2604 - 0.300307
mcm7 DDB_G0282933 similar to MCM7 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex DDB0232431 CDS12867 2370 + 0.319409
mcm8 DDB_G0283009 DDB0232431 CDS149067 2439 - 0.304633
mcm9 DDB_G0286035 DDB0232431 CDS3976133 3828 + 0.299373
mekA DDB_G0269152 STE SerThr protein kinase family mitogen-activated protein kinase kinase involved in chemotaxis and early development phosphorylates the MAP kinase Erk1 (erkA) is sumoyalated by sumo and ubiquinated by mip1 DDB0232428 CDS4015409 1983 - 0.252143
mf12 DDB_G0288067 DDB0232432 CDS1125741 4554 + 0.284365
mgmt DDB_G0275095 transfers methyl groups from DNA containing sup6supO-methylguanine to a cysteine residue DDB0232429 CDS5058865 618 - 0.237864
mkcA DDB_G0285427 similar to MAP cascade kinases belonging to the PAK sub-family of the STE20 serinethreonine kinases partial suppressor of tagB mutation DDB0232431 CDS3440715 2583 - 0.275648
mkcB DDB_G0290723 similar to Dictyostelium mkcA and other mitogen-activated protein kinases (Ste20PAK family) REMI mutant forms aberrant fruiting bodies see DDB0232432 CDS4499748 2145 + 0.332867
mkcC DDB_G0287853 kinase domain very similar to those of Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) DDB0232432 CDS826726 2676 + 0.342302
mkcD DDB_G0277413 similar to Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) DDB0232429 CDS7960057 1959 + 0.291986
mkcE DDB_G0281649 kinase domain similar to those of Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) DDB0232430 CDS4757942 2148 + 0.271881
mkcF DDB_G0270102 similar to Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) contains one SH3 (src Homology-3) domain DDB0232428 CDS4222376 2034 - 0.319076
mkkA DDB_G0283265 developmentally regulated MEKK DDB0232431 CDS530684 3804 + 0.287066
mlh1 DDB_G0287393 MLH1 ortholog required for DNA mismatch repair DDB0232432 CDS247623 2655 - 0.282109
mlh3 DDB_G0283883 MLH3 ortholog required for DNA mismatch repair DDB0232431 CDS1160700 4977 + 0.279687
mlkA DDB_G0279925 CAMK1 family protein kinase phosphorylates the myosin II regulatory light chain at S13 is not regulated by Ca2calmodulin DDB0232430 CDS2752719 888 - 0.317568
mnat1 DDB_G0289079 DDB0232432 CDS2330339 978 + 0.293456
mps1 DDB_G0280995 putative protein threoninetyrosine kinase similar to yeast and zebrafish mps1 (monopolar spindle) kinase a threoninetyrosine kinase DDB0232430 CDS3923506 2952 + 0.289295
mre11 DDB_G0293546 similar to S. cerevisiae MRE11 involved in processing double-strand DNA breaks with Rad50 in other organisms Mre11 is part of a complex with Rad50 and Nbs1 no Nbs1 ortholog has been found in Dictyostelium DDB0232433 CDS3016431 2070 + 0.304348
mrkA DDB_G0292304 CAMKL family protein kinase similar to MARK kinases SNF1 kinases and AMPK kinases contains 1 kinase-associated (KA1) domain and 1 UBA domain DDB0232433 CDS1433748 3183 - 0.286836
mrkB DDB_G0285643 CAMKL family protein kinase similar to SNF1 kinases MARK kinases and AMPK kinases DDB0232431 CDS3523048 2148 - 0.284916
mrkC DDB_G0281895 CAMKL family protein kinase similar to MARK kinases SNF1 kinases and AMPK kinases contains C-terminal kinase associated domain 1 DDB0232430 CDS5083659 2322 + 0.295866
msh1 DDB_G0275999 similar to bacterial mismatch repair protein MutS putative mitochondrial mismatch repair protein DDB0232429 CDS6158412 2697 - 0.251761
msh2 DDB_G0275809 DDB0232429 CDS5513128 2814 - 0.297797
msh3 DDB_G0281683 DDB0232430 CDS4806161 4287 + 0.292279
msh4 DDB_G0283957 DDB0232431 CDS1370478 3126 - 0.240883
msh5 DDB_G0284747 DDB0232431 CDS2423376 2643 - 0.239879
msh6 DDB_G0268614 DDB0232428 CDS238722 3783 + 0.335977
mus81 DDB_G0276519 similar to endonuclease Mus81 conserved from yeast to human involved in DNA repair and replication fork stability DDB0232429 CDS7009387 2763 - 0.239595
myh DDB_G0270764 ortholog of MYH which removes misincorporated adenine residues opposite template 8-oxoguanine during DNA replication DDB0232428 CDS4483000 1725 + 0.262029
ndrA DDB_G0278457 member of the AGC kinases NDR group localizes to centrosomes and to the spindle during prometaphase and is involved in phagocytosis DDB0232430 CDS907158 1593 + 0.344633
ndrB DDB_G0288753 member of the AGC kinase group similar to NDR protein kinases including yeast morphogenesis proteins ORB6 and CBK1 DDB0232432 CDS1909293 1629 - 0.324125
ndrC DDB_G0284839 member of the AGC kinase group NDR family related to mammalian LATS1 and LATS2 (LArge Tumor Suppressor homolog) kinases DDB0232431 CDS2493584 3939 + 0.307692
ndrD DDB_G0289543 member of the AGC kinase group NDR family related to mammalian LATS1 and LATS2 (LArge Tumor Suppressor homolog) kinases DDB0232432 CDS2920470 6339 + 0.255088
nek2 DDB_G0270814 protein serinethreonine kinase homologous to human Nek2 kinase involved in formation of microtubule-organizing centers (MTOCs) DDB0232428 CDS4847143 1257 - 0.258552
nek3 DDB_G0275241 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis not a human Nek3 homolog DDB0232429 CDS4983790 3372 - 0.269276
nek4 DDB_G0289277 similar to vertebrate Nek kinases which are involved in regulation of mitosis most similar to Nek4 DDB0232432 CDS2561379 1494 - 0.222222
ogg1 DDB_G0292618 similar to E. coli MutM and OGG1 a bifunctional DNA glycosylase that contains an activity that excises 8-oxoguanine and other derivatives of guanine from DNA and a beta-lyase activity that nicks DNA 3' of the lesion DDB0232433 CDS1847428 1320 - 0.258333
orcA DDB_G0283073 DNA replication initiation is driven by a conserved six protein complex the origin recognition complex (ORC) has a role in both chromosomal replication and mating type transcriptional silencing DDB0232431 CDS182130 1896 - 0.2827
orcB DDB_G0269894 DNA replication initiation is driven by a conserved six protein complex the origin recognition complex (ORC) has a role in both chromosomal replication and mating type transcriptional silencing DDB0232428 CDS3810811 1176 + 0.256803
orcD DDB_G0271562 DNA replication initiation is driven by a conserved six protein complex the origin recognition complex (ORC) has a role in both chromosomal replication and mating type transcriptional silencing DDB0232429 CDS681736 1323 + 0.226757
pXi DDB_G0289119 CAMK group protein serinethreonine kinase DDB0232432 CDS2420542 2076 - 0.25289
pakA DDB_G0269166 STE20PAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis contains PAK-boxP21-Rho-binding (CRIB) domain found in the WASP C-terminal DDB0232428 CDS3436536 3594 + 0.33222
pakB DDB_G0276459 protein serinethreonine kinase that phosphorylates myoD (myosin ID) and myoK (myosin IK) heavy chains similar to p21-activated kinase belongs to the STE20 family PAKA subfamily of protein kinases DDB0232429 CDS6847900 2559 - 0.339195
pakC DDB_G0267450 STE20PAK protein kinase required for normal chemotaxis contains PAK-boxP21-Rho-binding (CRIB) domain and pleckstrin homology (PH) domain DDB0232428 CDS229145 1434 - 0.33682
pakD DDB_G0269696 similar to Dictyostelium pakA and other mitogen-activated protein kinases (Ste20PAK family) putative p21-activated kinase contains a calponin-like actin-binding domain a p21-Rho-binding domain and a PKC conserved region 1 (C1) regulates the actin cytoskeleton response during chemotaxis to cAMP DDB0232428 CDS3345400 5037 + 0.25273
pakE DDB_G0293932 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232433 CDS3512665 2781 + 0.270766
pakF DDB_G0274409 putative protein serinethreonine kinase belongs to the protein kinase PAKL subfamily the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232429 CDS4648326 3531 - 0.282073
pakG DDB_G0282891 putative protein serinethreonine kinase belongs to the protein kinase PAKL subfamily the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DDB0232430 CDS6346144 3540 + 0.284181
pakH-1 DDB_G0273121 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases belongs to the PAKL subfamily stress-responsive kinase there is a second copy of this gene DDB0232429 CDS2532742 1542 + 0.282101
pakH-2 DDB_G0273865 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases belongs to the PAKL subfamilystress-responsive kinase there is a second copy of this gene DDB0232429 CDS3497296 1542 - 0.282101
pats1 DDB_G0269250 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR WD40 and protein kinase domains DDB0232428 CDS2657392 9555 - 0.289901
pcna DDB_G0287607 DDB0232432 CDS463300 777 - 0.352638
pdkA DDB_G0281471 member of the AGC kinase group similar to mammalian PDK (phosphoinositide-dependent protein kinase) known to phosphorylate AktPKB DDB0232430 CDS4550105 2061 - 0.273654
pdkB DDB_G0284489 member of the AGC kinase group similar to mammalian PDK (phosphoinositide-dependent protein kinase) known to phosphorylate AktPKB DDB0232431 CDS2038480 2727 + 0.260726
pfdn3 DDB_G0286473 DDB0232431 CDS4502996 588 - 0.268707
phg2 DDB_G0283699 serinethreonine kinase regulating cell substrate adhesion phagocytosis motility and actin organization member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats DDB0232431 CDS995559 4164 - 0.304275
pich DDB_G0288873 ortholog of human DNA excision repair protein ERCC-6-like (ERCC6L)br bCommunity annotation:b DDB_G0288873 but not ercc6 is strongly overexpressed (6x) in a Dicty strain in which the retinoblastoma-like gene rblA has been disrupted. Most cells involved in S-phase or mitosis are overexpressed in this strain. Ercc6-like is an essential component of the spindle checkpoint which localizes to the kinetochore in prometaphase it is found on thin threads that stretch between sister kinetochores. It is thought to function as part of the tension sensor the functional core of the spindle checkpoint [see Baumann et al Cell 128 101-114 (2007)]. Other spindle checkpoint components are strongly overexpressed in the rblA null. This suggests that DDB_G0288873 may actually code for the spindle tension sensor in Dicty. Harry MacWilliams May 2010br DDB0232432 CDS2065550 3999 - 0.295074
pif1 DDB_G0277925 very similar to the conserved DNA helicase PIF1 in S. cerevisiae involved in telomere formation and elongation DDB0232430 CDS12156 2010 - 0.283582
pikA DDB_G0278727 DDB0232430 CDS1154369 4716 + 0.261026
pikB DDB_G0283081 DDB0232431 CDS247398 5574 - 0.311805
pikC DDB_G0275011 DDB0232429 CDS5211773 5094 + 0.270907
pikD DDB_G0288485 subunit of PI4K responsible for the phosphorylation of phosphatidylinositol (PI) to PI4P (ATP 1-phosphatidyl-1D-myo-inositol ADP 1-phosphatidyl-1D-myo-inositol 4-phosphate) the first committed step in the generation of phosphatidylinositol 45-bisphosphate (PIP2) a precursor of the second messenger inositol 145-trisphosphate (InsP3) DDB0232432 CDS1616073 3543 + 0.269828
pikE DDB_G0289601 ortholog of yeast VPS34 a phosphatidylinositol 3-kinase DDB0232432 CDS3005109 2451 - 0.299878
pikF DDB_G0268548 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras DDB0232428 CDS1099622 4149 + 0.291396
pikG DDB_G0282625 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras DDB0232430 CDS6013022 5016 - 0.234649
pikH DDB_G0291093 putative PI3k putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring unlike other PI3Ks does not contain a ras binding domain but a PH domain and does not localize to the cell cortex upon chemotactic stimulation DDB0232432 CDS4980832 5463 - 0.242541
pkaC DDB_G0283907 AGC group PKA family protein kinase protein serinethreonine kinase regulates spore cell differentiation DDB0232431 CDS1394958 1947 + 0.333847
pkaD DDB_G0277145 DDB0232429 CDS7643321 2145 - 0.253613
pkbA DDB_G0268620 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation DDB0232428 CDS1977388 1335 + 0.357303
pkgA DDB_G0276157 serinethreonine protein kinase of the MAST (Microtubule Associated SerineThreonine kinase) family DDB0232429 CDS6275918 4104 - 0.287037
pkgB DDB_G0290157 AGC group protein serinethreonine kinase cAMP-activated protein kinase involved in morphogenesis during multicellular development DDB0232432 CDS3717777 1440 - 0.324306
pkgC DDB_G0286125 serinethreonine protein kinase of the AGC group similar to mammalian ribosomal protein S6 kinase DDB0232431 CDS4067973 2733 - 0.312843
pkgD DDB_G0284029 AGC group protein serinethreonine kinase similar to cAMP-activated protein kinase catalytic subunits DDB0232431 CDS1459718 2979 - 0.28231
pkgE_ps DDB_G0280981 putative pseudogene similar to AGC protein kinases of the AKT family DDB0232430 CDS3912677 1095 + 0.343379
plk DDB_G0274503 putative protein serinethreonine kinase similar to yeast CDC5 Drosophila polo and mammalian PLK which play a role in mitosis and localize to the centrosomes DDB0232429 CDS4379150 2937 - 0.280899
pms1 DDB_G0283981 ortholog of H. sapiens PMS2 and S. cerevisiae PMS1 required for DNA mismatch repair DDB0232431 CDS1418066 3069 - 0.273053
polA DDB_G0267464 contains one 5'-3' exonuclease domain and one 3'-5' exonuclease domain DDB0232428 CDS1469084 4110 - 0.29708
polA1 DDB_G0282191 ortholog of the catalytic subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication DDB0232430 CDS5500018 4530 + 0.305519
polA2 DDB_G0282731 ortholog of the B subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication DDB0232430 CDS6220731 1872 + 0.280983
polA3 DDB_G0270442 ortholog of the DNA primase large subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication DDB0232428 CDS4882826 1413 - 0.279547
polA4 DDB_G0285853 ortholog of the DNA primase small subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication DDB0232431 CDS3724070 1230 - 0.281301
polB DDB_G0284713 similar to yeast Pol4 and mammalian DNA polymerase beta involved in repair of DNA double-strand breaks by non-homologous end joining (NHEJ) DDB0232431 CDS2376164 1530 - 0.261438
polD1 DDB_G0285381 required for chromomsomal DNA replication contains a polymerase and a 3'-5' exonuclease domain DDB0232431 CDS3206066 3315 - 0.332428
polD2 DDB_G0281641 DDB0232430 CDS4748825 1566 - 0.288633
prpf4B DDB_G0279703 protein serinethreonine kinase DYRK family member of the CMGC kinase group similar to mammalian pre-mRNA processing factor PRP4 kinase and DYRK kinases DDB0232430 CDS2466144 2436 + 0.296388
pyk3 DDB_G0289001 member of the TKL (tyrosine kinase-like) group and the DPYK (Dictyostelium protein tyrosine kinase) family of protein kinases contains two kinase domains one of which is predicted to be inactive the C-terminal kinase domain has tyrosine kinase activitybr bCommunity annotation:b Pyk3 appears to be involved in differentiation pathway choice as the KO shows reduced pstO differentiation and compensatory expansion of the prespore region. Pyk3 has been proposed to act in a pathway involving ptpC and statC effectively potentiating the action of DIF-1. One of the factors that influences pathway choice is cell cycle position classic experiments show that cold-synchronized cells which enter development shortly after warming prefer the stalk pathway. This is due to an increased DIF sensitivity. New results (Strasser Tsang and MacWilliams in preparation) now show that the pyk3 transcript is upregulated roughly fivefold after cold synchronization at a time when cells show strong stalk preference (p DDB0232432 CDS2269413 4017 - 0.283047
qkgA-1 DDB_G0273259 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains there is a second copy of this gene DDB0232429 CDS2831844 4662 + 0.27885
qkgA-2 DDB_G0273635 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains there is a second copy of this gene DDB0232429 CDS3195191 4662 - 0.27885
rad17 DDB_G0292504 similar to S. pombe and H. sapiens RAD17 and S. cerevisiae RAD24 component of Rad17-RFC complex which loads the 9-1-1 (Rad9-Rad1-Hus1) complex onto damaged DNA DDB0232433 CDS1748396 3576 + 0.245526
rad50 DDB_G0292786 similar to S. cerevisiae RAD50 involved in processing double-strand DNA breaks with Mre11 in other organisms Rad50 is part of a complex with Mre11 and Nbs1 no Nbs1 ortholog has been found in Dictyostelium DDB0232433 CDS2029933 4056 + 0.272189
rad51-1 DDB_G0273139 ortholog of Rad51 which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3 there is a second copy of this gene DDB0232429 CDS2861364 1056 - 0.344697
rad51-2 DDB_G0273611 ortholog of Rad51 which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3 there is a second copy of this gene DDB0232429 CDS3169189 1056 + 0.344697
rad52 DDB_G0269406 DDB0232428 CDS2715190 906 - 0.364238
rad54 DDB_G0282997 similar to RAD54 DNA repair protein chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232431 CDS118731 2796 + 0.33226
rad54b DDB_G0285117 similar to RAD54b DNA repair protein chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DDB0232431 CDS2873116 2970 - 0.278788
rcdII DDB_G0284041 DDB0232431 CDS1500251 1395 - 0.26595
rckA DDB_G0278737 member of the TKL (tyrosine kinase-like) group contains an RGS (Regulator of G protein Signaling) domain DDB0232430 CDS1218919 3378 + 0.261693
recA DDB_G0276073 similar to recombinase A proteins found in bacteria and in A. thaliana plays a role in DNA repair DDB0232429 CDS6430683 1359 - 0.288447
repB DDB_G0278729 ortholog of H. sapiens xeroderma pigmentosum group B (XPB) M. musculus ERCC3 and S. cerevisiae RAD25 upregulated in the presence of DNA damaging agents DDB0232430 CDS1389108 2403 + 0.33042
repD DDB_G0267414 ortholog of H. sapiens xeroderma pigmentosum group D (XPD) M. musculus ERCC2 and S. cerevisiae RAD3 DDB0232428 CDS833130 2331 - 0.33891
repG DDB_G0284987 similar to H. sapiens xeroderma pigmentosum group G (XPG) M. musculus ERCC5 and S. pombe RAD2 cleaves 5' overhang flap structure generated when DNA polymerase encounters the 5'end of a downstream Okazaki fragment DDB0232431 CDS2762877 1155 - 0.309091
rev3 DDB_G0271608 ortholog of DNA polymerase zeta catalytic subunit involed in DNA repair DDB0232429 CDS480277 8106 + 0.253886
rexo4 DDB_G0281327 DDB0232430 CDS4193116 897 + 0.235229
rfa1 DDB_G0289513 DDB0232432 CDS2891660 2040 + 0.320098
rfc1 DDB_G0285961 ortholog of H. sapiens RFC 140 kDa subunit DDB0232431 CDS3845828 4206 + 0.3136
rfc2 DDB_G0291868 ortholog of H. sapiens RFC2 (40 kDa subunit) and S. cerevisiae RFC2 DDB0232433 CDS850606 1017 + 0.328417
rfc3 DDB_G0293702 ortholog of H. sapiens RFC3 (38 kDa subunit) and S. cerevisiae RFC5 DDB0232433 CDS3014705 1044 - 0.331418
rfc4 DDB_G0286027 ortholog of H. sapiens RFC4 (37 kDa subunit) and S. cerevisiae RFC2 DDB0232431 CDS3966261 1044 + 0.314176
rfc5 DDB_G0282235 ortholog of H. sapiens RFC5 (36 kDa subunit) and S. cerevisiae RFC3 DDB0232430 CDS5553806 1044 + 0.267241
rnaseh2A DDB_G0292584 catalytic subunit of RNase HII an endonuclease that specifically degrades the RNA of RNA:DNA hybrids defects in H. sapiens RNASEH2A cause Aicardi-Goutieres syndrome type 4 a genetically heterogeneous autosomal recessive encephalopathy DDB0232433 CDS1802425 870 - 0.287356
roco11 DDB_G0268636 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains DDB0232428 CDS2199646 4464 + 0.267473
roco4 DDB_G0288251 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains DDB0232432 CDS1284583 5181 + 0.332947
roco5 DDB_G0294533 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains RhoGEF PH LRR Roc COR and protein kinase domains DDB0232432 CDS1439427 8403 - 0.309413
roco6 DDB_G0279417 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR WD40 PH and protein kinase domains DDB0232430 CDS2094570 6444 + 0.293451
roco7 DDB_G0267472 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains Roc COR WD40 and protein kinase domains related to LRR-containing kinases but does not contain an LRR domain DDB0232428 CDS628403 7848 - 0.293833
roco8 DDB_G0286127 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains DEP LRR Roc COR and protein kinase domains DDB0232431 CDS4112361 5604 - 0.267131
roco9 DDB_G0288183 member of the TKL (tyrosine kinase-like) group and ROCO family of protein kinases contains RhoGAP LRR Roc Cor and protein kinase domains DDB0232432 CDS1219231 10098 - 0.264706
rpa49 DDB_G0290909 component of the RNA polymerase I complex weakly similar to S. cerevisiae RPA49 and M. musculus RNA polymerase I associated factor 53 DDB0232432 CDS4737794 1128 + 0.265957
rrpA DDB_G0289659 DDB0232432 CDS3196021 7254 + 0.263441
rrpB DDB_G0291249 one of the three D. discoideum RNA-directed RNA polymerases for which a distinct function has not yet been identified DDB0232433 CDS442657 7212 - 0.266916
rrpC DDB_G0280963 RNA-directed RNA polymerase involved in RNA interference and the production of siRNA also involved in the metabolism of other miRNAs DDB0232430 CDS3986737 6858 + 0.247302
samkA DDB_G0269876 DDB0232428 CDS3775693 1923 + 0.228289
samkB DDB_G0284859 putative protein kinase containing a SAM (sterile alpha motif) homology domain a putative protein interaction module DDB0232431 CDS2549067 1782 + 0.251403
samkB_ps1 DDB_G0270988 putative pseudogene SAMK (SAM domain-containing kinase) family DDB0232428 CDS3791042 1593 - 0.264909
samkC DDB_G0270678 putative protein kinase containing a SAM (sterile alpha motif) homology domain a putative protein interaction module DDB0232428 CDS3778203 2628 + 0.251903
samkD DDB_G0270680 similar to SNF1-like kinases unlikely to function as a kinase as it lacks the catalytic aspartate DDB0232428 CDS3781297 1662 + 0.197954
samkE_ps1 DDB_G0283165 putative pseudogene SAMK (SAM domain-containing kinase) family DDB0232431 CDS352482 1272 - 0.26022
sepA DDB_G0276465 plays a role in the regulation of cleavage furrow formation similar to S. pombe cdc7 DDB0232429 CDS6942806 3504 + 0.32363
shkA DDB_G0283267 member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily contains a C-terminal SH2 (Src homology 2) domain negative regulator of phosphoinositol signaling DDB0232431 CDS438511 1584 + 0.318182
shkB DDB_G0288617 member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily contains a C-terminal SH2 (Src homology 2) domain DDB0232432 CDS1745652 1962 - 0.331295
shkC DDB_G0278409 member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily contains a C-terminal SH2 (Src homology 2) domain DDB0232430 CDS836437 1521 - 0.332676
shkD DDB_G0281343 member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily contains a C-terminal SH2 (Src homology 2) domain DDB0232430 CDS4376038 2235 + 0.314541
shkE DDB_G0290451 member of the TKL (tyrosine kinase-like) group and the SHK (SH2-domain containing kinase) subfamily contains a C-terminal SH2 (Src homology 2) domain DDB0232432 CDS4058161 2133 + 0.284107
sky1 DDB_G0275627 similar to SRPKs (Serinearginine-Rich Protein specific Kinases) serinethreonine kinases that specifically phosphoryate arginine-serine rich domains found in the SR family of splicing factors DDB0232429 CDS5951942 1971 - 0.318113
smg1 DDB_G0275845 atypical PIKK family protein kinase similar to the PI-3-kinase-related kinase SMG1 which functions in nonsense-mediated mRNA decay belongs to the PIKK family of protein kinases DDB0232429 CDS5665840 7035 + 0.267235
snf2a DDB_G0285205 SNF2 family protein similar to human SMARCA4 putative regulator of chromatin DDB0232431 CDS2921996 4815 + 0.304673
snf2b DDB_G0271052 SNF2 family protein similar to human SMARCA4 putative regulator of chromatin DDB0232428 CDS4502537 9744 - 0.313218
snfA DDB_G0277905 CAMKL family protein kinase catalytic subunit of the AMP-activated protein kinase (AMPK) complex similar to SNF1 kinases and AMPK experiments in Dictyostelium show that AMPK signaling plays an important role in mitochondrial disease. DDB0232430 CDS589784 2184 + 0.250458
spkA-1 DDB_G0273445 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene DDB0232429 CDS2969377 1917 - 0.310381
spkA-2 DDB_G0273531 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene DDB0232429 CDS3060166 1917 + 0.310381
splA DDB_G0283385 dual-specificity protein kinase involved in spore coat formation and morphogenesis member of the TKL (tyrosine kinase-like) group and the CZAK (C-terminal domain of ZakA) family DDB0232431 CDS623097 7233 + 0.323655
splB DDB_G0285321 member of the TKL (tyrosine kinase-like) group activates the transcriptional regulator STATc DDB0232431 CDS3131349 3468 + 0.27797
spt16 DDB_G0282677 similar to SPT16 of the FACT complex a heterodimer of ssrp1 and spt16 the FACT complex is a general chromatin factor that acts to reorganize nucleosomes involved in multiple processes that require DNA as a template such as mRNA elongation DNA replication and DNA repair DDB0232430 CDS6105920 3219 - 0.339546
spt16_ps DDB_G0282775 putative pseudogene similar to D. discoideum gene DDB0232430 CDS5907328 582 + 0.359107
sqpA DDB_G0277873 DDB0232430 CDS467909 2169 + 0.244813
ssrp1 DDB_G0290331 ortholog of the SSRP1 component of the FACT complex a heterodimer of ssrp1 and spt16 the FACT complex is a general chromatin factor that acts to reorganize nucleosomes involved in multiple processes that require DNA as a template such as mRNA elongation DNA replication and DNA repair DDB0232432 CDS3969916 1584 - 0.342172
sun1 DDB_G0272869 localizes to the inner and outer nuclear membrane mediates the attachment between centrosome and nucleus associates the centromere cluster with the centrosome and stabilizes the genome during mitosis contains one transmembrane domain DDB0232429 CDS2057584 2718 - 0.270419
svkA DDB_G0286359 very similar to mammalian ST25 kinase (SOK1) and other STE20-like kinases stress-responsive kinase phosphorylates severin essential for cell separation during cytokinesis DDB0232431 CDS4476218 1437 + 0.343076
thoc7 DDB_G0275979 ortholog of THOC7 which exists in the THO complex required for transcriptional elongation DDB0232429 CDS6151550 648 + 0.225309
tifA DDB_G0269192 similar to eukaryotic initiation factor 4A isoform 3 DDB0232428 CDS3537960 1218 + 0.316092
tmem120 DDB_G0288699 conserved transmembrane protein contains 4 putative transmembrane domains DDB0232432 CDS1842289 1107 - 0.311653
top1 DDB_G0283205 ortholog of TOP1 a nuclear topoisomerase responsible for relaxing single-stranded supercoiled DNA DDB0232431 CDS416900 2682 + 0.35123
top2 DDB_G0270418 controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands this is predicted to be a nuclear topoisomerase II DDB0232428 CDS4831688 4566 - 0.329172
top2mt DDB_G0279737 controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands Top2mt has been shown to be localized to the mitochondria DDB0232430 CDS2512313 3855 - 0.284566
top3 DDB_G0275257 ortholog of TOP3 a nuclear topoisomerase responsible for relaxing single-stranded negatively-supercoiled DNA DDB0232429 CDS5038466 2487 - 0.300362
tor DDB_G0281569 atypical PIKK family FRAP subfamily protein kinase ortholog of tor a protein kinase that plays a central role in response to nutrients stress and intracellular energy state called mTOR in mammals in dTOR in Drosophila DDB0232430 CDS4934791 7143 - 0.347893
trmt11 DDB_G0283969 DDB0232431 CDS1400103 1524 + 0.270341
tsuA DDB_G0267962 putative protein serinethreonine kinase similar to mammalian STK36 and fly fused kinase (fu) a ST kinase involved in the hedgehog signal transduction pathway belongs to the ULK (Unc-51-like kinase) family of kinases DDB0232428 CDS1191800 6744 + 0.248517
u2af1 DDB_G0285077 small subunit of the U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) which is a splicing factor that forms a heterodimer with DDB0232431 CDS2799520 1416 + 0.366525
uap56 DDB_G0269932 conserved splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint the human ortholog (BAT1) forms a homodimer and interacts directly with DDB0232428 CDS3893359 1287 - 0.359751
uglA DDB_G0277877 DDB0232430 CDS330250 1041 + 0.332373
uglB DDB_G0273013 DDB0232429 CDS2160250 1794 - 0.230769
upf1 DDB_G0288923 ortholog of yeast NAM7 and the mammalian UPF1 (up-frameshift suppressor 1) or RENT1 protein part of a post-splicing multiprotein complex and involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons DDB0232432 CDS2130048 3996 + 0.318068
vilC DDB_G0271058 belongs to the villingelsolin family contains 5 gelsolin-like repeats and one villin headpiece domain DDB0232428 CDS4570908 4587 - 0.297362
vinB DDB_G0281499 DDB0232430 CDS4621318 5355 + 0.320635
vps15 DDB_G0282627 putative protein serinethreonine kinase similar to human PIK3R4 and yeast VPS15 which regulate the phosphatidylinositol 3 kinase VPS34 (hVps34) yeast VPS15VPS34 complex known to be involved in vacuolar protein sorting DDB0232430 CDS6019111 5901 + 0.306219
vti1A DDB_G0292974 DDB0232433 CDS2202494 654 - 0.281346
wrn DDB_G0268512 E. coli ATP-dependent DNA helicase RecQ is involved in genome maintenance this is the ortholog of the H. sapiens Werner syndrome protein defects in WRN cause the premature onset of multiple age-related disorders DDB0232428 CDS769229 3411 - 0.230431
wrnip1 DDB_G0272158 ortholog of Werner helicase-interacting protein 1 a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis DDB0232429 CDS1585133 2631 + 0.302547
xpc DDB_G0292296 DDB0232433 CDS1414792 2904 + 0.266529
xpf DDB_G0284419 DDB0232431 CDS1971161 2895 + 0.245596
xrcc2 DDB_G0290297 putative ortholog of XRCC2 which is involved in double-strand break repair interacts with RAD51 DDB0232432 CDS3921390 1167 + 0.251928
xrcc3 DDB_G0283637 putative ortholog of XRCC3 which is involved in double-strand break repair interacts with RAD51 DDB0232431 CDS893273 1695 + 0.220059
xrn1 DDB_G0276137 DDB0232429 CDS6232603 5250 - 0.333333
xrn2 DDB_G0269922 DDB0232428 CDS3871046 3573 - 0.285195
yakA DDB_G0283605 belongs to the CMGC group of protein kinases putative protein serinethreonine kinase DDB0232431 CDS868454 4377 + 0.303404
ybl1 DDB_G0272222 member of the histone H2A-H2B sub-family related to the NF-YB subunit of the CCAAT-binding activator NF-Y DDB0232429 CDS1710917 417 - 0.297362
zak2 DDB_G0276187 contains two kinase domains N-terminal kinase domain related to STE group C-terminal domain similar to TKL group highly similar to zakA and has overlapping function with zakA shown to be a tyrosine kinase and regulator of GSK3 also regulates pattern formation during development via dstC (STATc) signaling DDB0232429 CDS6396810 1908 - 0.253145
zakA DDB_G0276025 contains two kinase domains N-terminal kinase domain related to STE group C-terminal domain similar to TKL group DDB0232429 CDS6393550 2346 - 0.239983
 
Dictyostelium fasciculatum, SH3
NameLocus tagProduct / DescriptionUniProt / TrEMBL protein nameGenomic elementTypeBeginLengthStrandGC-content
g10005 DFA_10387 EU5ZYIE02H8LDV-5 CDS1381021 924 + 0.33658
g10181 DFA_10589 EU5ZYIE02H8LDV-5 CDS1809881 5799 + 0.336092
g10244 DFA_10649 EUAJFUG01CK1KI-5 CDS54327 1512 - 0.478836
g10251 DFA_10656 EUAJFUG01CK1KI-5 CDS73401 2589 - 0.278872
g10309 DFA_10717 EUAJFUG01CK1KI-5 CDS233982 3825 + 0.333595
g1036 DFA_01028 Dfasci-F-a-25c12.r2-5 CDS1780022 909 + 0.343234
g10379 DFA_10793 EUAJFUG01CK1KI-5 CDS394263 4482 - 0.309014
g10389 DFA_10803 EUAJFUG01CK1KI-5 CDS418729 2145 + 0.339394
g10405 DFA_10822 EUAJFUG01CK1KI-5 CDS456937 1461 + 0.372348
g10436 DFA_10853 EUAJFUG02G6ADK-5 CDS961 2310 - 0.308225
g10448 DFA_10865 EUAJFUG02G6ADK-5 CDS32353 975 + 0.386667
g10536 DFA_10955 EUAJFUG02G6ADK-5 CDS225912 3171 - 0.353516
g10547 DFA_10967 EUAJFUG02G6ADK-5 CDS265815 6345 + 0.321355
g10567 DFA_10988 EUAJFUG02G6ADK-5 CDS319842 2610 - 0.34023
g1059 DFA_01049 Dfasci-F-a-25c12.r2-5 CDS1835263 5838 + 0.341555
g10601 DFA_11020 EUAJFUG02HR96I-5 CDS11751 1788 - 0.326063
g10612 DFA_11030 EUAJFUG02HR96I-5 CDS29011 2631 + 0.341695
g10618 DFA_11036 EUAJFUG02HR96I-5 CDS42665 759 - 0.334651
g10623 DFA_11042 EUAJFUG02HR96I-5 CDS55245 3189 + 0.337096
g10653 DFA_11070 EUAJFUG02HR96I-5 CDS120444 4674 - 0.312152
g10719 DFA_11133 EUAJFUG02HR96I-5 CDS299932 4821 + 0.367144
g10720 DFA_11134 EUAJFUG02HR96I-5 CDS305359 6858 + 0.371537
g10755 DFA_11172 EUAJFUG02HR96I-5 CDS404889 4089 - 0.297383
g10757 DFA_11174 EUAJFUG02HR96I-5 CDS411077 1695 - 0.316224
g10820 DFA_11241 EUAJFUG02HR96I-5 CDS577896 3198 + 0.514384
g10828 DFA_11248 EUAJFUG02HR96I-5 CDS601931 4476 - 0.454647
g10837 DFA_11259 EUAJFUG02HR96I-5 CDS631023 3354 - 0.386404
g1087 DFA_01077 Dfasci-F-a-25c12.r2-5 CDS1905423 5979 - 0.441378
g10940 DFA_11355 EUAJFUG02HR96I-5 CDS921600 4107 - 0.445581
g10945 DFA_11360 EUAJFUG02HR96I-5 CDS938394 2544 - 0.397013
g1095 DFA_01086 Dfasci-F-a-25c12.r2-5 CDS1929571 3159 + 0.369421
g10958 DFA_11373 EUAJFUG02HR96I-5 CDS971623 1242 + 0.407407
g10961 DFA_11376 EUAJFUG02HR96I-5 CDS978365 3486 - 0.441767
g10974 DFA_11390 EUAJFUG02HR96I-5 CDS1006926 2799 - 0.346552
g10994 DFA_11412 EUAJFUG02HR96I-5 CDS1050472 12909 - 0.37989
g11008 DFA_11425 EUAJFUG02HR96I-5 CDS1093722 1419 - 0.362227
g11020 DFA_11439 EUAJFUG02HR96I-5 CDS1123802 1713 + 0.365441
g11022 DFA_11441 EUAJFUG02HR96I-5 CDS1128998 1068 + 0.351124
g11023 DFA_11442 EUAJFUG02HR96I-5 CDS1130734 843 + 0.335706
g11025 DFA_11443 EUAJFUG02HR96I-5 CDS1133206 969 - 0.337461
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g9716 DFA_10088 EU5ZYIE02H8LDV-5 CDS699087 2433 + 0.389642
g9762 DFA_10137 EU5ZYIE02H8LDV-5 CDS813176 1308 + 0.324924
g9782 DFA_10158 EU5ZYIE02H8LDV-5 CDS855899 990 + 0.356566
g979 DFA_00972 Dfasci-F-a-25c12.r2-5 CDS1626491 5001 - 0.370726
g9795 DFA_10173 EU5ZYIE02H8LDV-5 CDS889406 3819 - 0.40089
g9809 DFA_10189 EU5ZYIE02H8LDV-5 CDS925949 1470 + 0.393197
g9847 DFA_10225 EU5ZYIE02H8LDV-5 CDS1020201 4944 + 0.397856
g9928 DFA_10309 EU5ZYIE02H8LDV-5 CDS1204768 1911 - 0.455259
g9930 DFA_10310 EU5ZYIE02H8LDV-5 CDS1208026 3387 + 0.402421
g998 DFA_00991 Dfasci-F-a-25c12.r2-5 CDS1687457 1695 + 0.351032
g9986 DFA_10370 EU5ZYIE02H8LDV-5 CDS1336286 5694 - 0.304882
 
Dictyostelium lacteum
NameLocus tagProduct / DescriptionUniProt / TrEMBL protein nameGenomic elementTypeBeginLengthStrandGC-content
g10022 DLA_11184 GLQOFTK02JL55Q CDS639909 2118 - 0.315392
g10043 DLA_11206 GLQOFTK02JL55Q CDS683801 1260 - 0.281746
g10044 DLA_11207 GLQOFTK02JL55Q CDS685183 1239 - 0.297014
g10048 DLA_11211 similar to MCM6 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex GLQOFTK02JL55Q CDS691323 2565 - 0.332164
g1007 DLA_01117 F4PJNLW01A00V1 CDS843560 7092 + 0.326424
g10075 DLA_11248 GLQOFTK02JL55Q CDS756239 1938 + 0.288958
g10106 DLA_11284 GLQOFTK02JL55Q CDS823910 2478 + 0.307103
g10109 DLA_11287 GLQOFTK02JL55Q CDS829023 804 - 0.298507
g10113 DLA_11293 hydrolyses alkylated adenine residues on DNA releasing 3-methyladenine GLQOFTK02JL55Q CDS836557 678 + 0.306785
g10123 DLA_11305 GLQOFTK02JL55Q CDS865248 873 + 0.353952
g10139 DLA_11326 DEADDEAH box helicases are involved in various aspects of RNA metabolism GLQOFTK02JL55Q CDS904155 1899 + 0.319115
g10154 DLA_11344 GLQOFTK02JL55Q CDS936163 1962 + 0.284913
g10222 DLA_11418 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation newcontig00824_1.exp CDS58027 1758 + 0.306598
g1097 DLA_01213 F4PJNLW01A00V1 CDS1034101 2148 - 0.366853
g1137 DLA_01255 F4PJNLW01A00V1 CDS1143780 1638 + 0.310745
g1144 DLA_01262 F4PJNLW01A00V1 CDS1157028 3807 - 0.353297
g1167 DLA_01284 F4PJNLW01A00V1 CDS1225330 4419 - 0.342838
g1215 DLA_01337 F4PJNLW01A00V1 CDS1341753 5667 - 0.341803
g1236 DLA_01359 protein serinethreonine kinase homologous to human Nek2 kinase involved in formation of microtubule-organizing centers (MTOCs) F4PJNLW01A00V1 CDS1401955 1134 - 0.308642
g1258 DLA_01381 F4PJNLW01A00V1 CDS1444033 1494 + 0.281125
g1302 DLA_01426 putative protein serinethreonine kinase the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases stress-responsive kinase F4PJNLW01B0TO9 CDS27222 3570 + 0.333333
g1322 DLA_01446 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases F4PJNLW01B0TO9 CDS66765 1326 - 0.33635
g1326 DLA_01452 F4PJNLW01B0TO9 CDS76843 4308 + 0.333798
g1332 DLA_01462 F4PJNLW01B0TO9 CDS92167 1032 + 0.300388
g1348 DLA_01478 putative protein serinethreonine kinase GSK family member of the CMGC kinase group similar to Drosophila shaggy and other glycogen synthase kinases F4PJNLW01B0TO9 CDS135859 1329 - 0.346877
g1354 DLA_01484 F4PJNLW01B0TO9 CDS149734 3606 - 0.344981
g136 DLA_00157 contig05409_1.exp CDS313401 3300 + 0.308182
g1387 DLA_11481 F4PJNLW01B0TO9 CDS220295 465 + 0.378495
g140 DLA_00163 contig05409_1.exp CDS327309 2994 + 0.327321
g1409 DLA_01545 F4PJNLW01B0TO9 CDS262242 1941 + 0.327666
g1413 DLA_01549 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation F4PJNLW01B0TO9 CDS268569 1326 - 0.36727
g142 DLA_00165 contig05409_1.exp CDS332861 1857 + 0.325256
g144 DLA_00167 contig05409_1.exp CDS337749 2379 - 0.349306
g1527 DLA_01674 E.coli ATP-dependent DNA helicase RecQ is involved in genome maintenance similar to Bloom syndrome protein defects in BLM cause genetic instability including a high level of sister chromatid exchanges associated with a greatly increased predisposition to a wide range of cancers F4PJNLW01B0TO9 CDS522200 2244 - 0.315062
g1548 DLA_01696 F4PJNLW01B0TO9 CDS576002 3606 - 0.311425
g1549 DLA_11488 F4PJNLW01B0TO9 CDS580805 2460 + 0.387398
g1550 DLA_01697 F4PJNLW01B0TO9 CDS583710 5862 + 0.360628
g1565 DLA_01717 catalyses the endonucleolytic cleavage of apurinic or apyrimidinic sites to generate products with a 5'-phosphate there is a second copy of this gene F4PJNLW01B0TO9 CDS619613 828 - 0.317633
g1606 DLA_01758 F4PJNLW01B0TO9 CDS707303 1743 - 0.327022
g1618 DLA_01772 F4PJNLW01B0TO9 CDS729828 1833 - 0.333879
g162 DLA_00188 contig05409_1.exp CDS376542 1929 + 0.369103
g1668 DLA_01824 F4PJNLW01B0TO9 CDS846981 2520 + 0.289286
g1691 DLA_01851 F4PJNLW01B0TO9 CDS905167 3105 - 0.335266
g1697 DLA_01857 F4PJNLW01B0TO9 CDS918129 1437 - 0.347251
g1700 DLA_01860 F4PJNLW01B0TO9 CDS924680 4245 - 0.345112
g1701 DLA_01861 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase F4PJNLW01B0TO9 CDS929551 2454 + 0.332926
g1728 DLA_01892 F4PJNLW01B0TO9 CDS988245 3060 + 0.32451
g1751 DLA_01915 belongs to a superfamily of metalloenzymes induced by Legionella pneumophila infection F4PJNLW01B3KKL CDS5796 1023 + 0.297165
g1794 DLA_01957 F4PJNLW01C9MXC CDS67445 2940 + 0.339796
g1833 DLA_01998 F4PJNLW01C9MXC CDS161915 1767 + 0.367855
g1889 DLA_02061 F4PJNLW01CH19P CDS96374 2988 - 0.351406
g1898 DLA_11513 F4PJNLW01DERRH CDS15159 2400 + 0.26375
g1909 DLA_02083 F4PJNLW01DERRH CDS52075 2175 - 0.308506
g1935 DLA_02117 F4PJNLW01DERRH CDS124838 2322 - 0.314384
g1976 DLA_02166 F4PJNLW01DERRH CDS222365 723 - 0.305671
g1978 DLA_02169 F4PJNLW01DERRH CDS225983 1635 - 0.329664
g1985 DLA_02178 putative RNA helicase contains an RWD domain (RING finger and WD repeat) F4PJNLW01DERRH CDS241601 4122 - 0.318535
g2022 DLA_02221 member of the TKL (tyrosine kinase-like) group contains a galactose oxidase central domain and three Kelch motifs F4PJNLW01DERRH CDS331361 3084 + 0.336576
g2035 DLA_02237 F4PJNLW01DERRH CDS361545 1866 + 0.369775
g2049 DLA_02252 F4PJNLW01DERRH CDS385220 5760 + 0.336111
g2055 DLA_02260 DEADDEAH box helicases are involved in various aspects of RNA metabolism F4PJNLW01DERRH CDS399702 2160 + 0.346296
g2071 DLA_02277 F4PJNLW01DERRH CDS430969 1344 + 0.3125
g2102 DLA_02316 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation F4PJNLW01DERRH CDS492601 1605 + 0.316511
g2105 DLA_02319 F4PJNLW01DERRH CDS497752 2889 + 0.283143
g2124 DLA_02339 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW01DERRH CDS552865 1164 - 0.34622
g2162 DLA_02380 member of the AGC kinase group similar to kinase domains of NDR (nuclear Dbf2-related) and MAST (microtubule-associated serinethreonine kinase) F4PJNLW01DERRH CDS633835 4887 + 0.331492
g2173 DLA_02393 F4PJNLW01DERRH CDS660867 1635 + 0.310703
g2174 DLA_02394 F4PJNLW01DERRH CDS662630 2847 - 0.336495
g2175 DLA_02395 F4PJNLW01DERRH CDS665801 1602 + 0.303371
g2181 DLA_02401 F4PJNLW01DERRH CDS675835 1575 + 0.290159
g2206 DLA_02429 F4PJNLW01EE5MJ CDS154 1812 + 0.312362
g2236 DLA_02470 F4PJNLW01EE5MJ CDS81014 1212 + 0.285479
g2260 DLA_02495 F4PJNLW01EE5MJ CDS138880 2247 - 0.365821
g2282 DLA_02524 F4PJNLW01EE5MJ CDS198242 2193 - 0.336981
g2306 DLA_02550 F4PJNLW01EE5MJ CDS260902 897 - 0.338907
g2364 DLA_02614 F4PJNLW01EE5MJ CDS365601 5229 - 0.347676
g2426 DLA_02687 F4PJNLW01EE5MJ CDS499115 4104 + 0.34308
g2428 DLA_02691 F4PJNLW01EE5MJ CDS508852 2733 + 0.320161
g2455 DLA_02725 F4PJNLW01EE5MJ CDS579082 2658 - 0.322047
g2464 DLA_02733 F4PJNLW01EE5MJ CDS603644 5577 - 0.337637
g2473 DLA_02744 F4PJNLW01EE5MJ CDS624351 3513 + 0.317108
g2488 DLA_02759 F4PJNLW01EE5MJ CDS667342 6816 + 0.359008
g2514 DLA_02788 F4PJNLW01EE5MJ CDS721035 2421 + 0.327551
g2520 DLA_02794 F4PJNLW01EE5MJ CDS732818 813 - 0.341943
g2528 DLA_02802 ortholog of the human DHX9 that unwinds double-stranded DNA and RNA in a 3' to 5' direction F4PJNLW01EE5MJ CDS751371 4032 - 0.312252
g2542 DLA_02816 F4PJNLW01EE5MJ CDS781075 2442 + 0.285831
g2578 DLA_02861 F4PJNLW01EE5MJ CDS864104 2604 - 0.320276
g2586 DLA_02869 F4PJNLW01EE5MJ CDS880997 1695 + 0.315634
g2620 DLA_02908 F4PJNLW01EE5MJ CDS969208 3174 - 0.333018
g2636 DLA_02926 F4PJNLW01EE5MJ CDS1000811 2118 - 0.344193
g270 DLA_00300 contig05409_1.exp CDS625941 2418 + 0.35732
g2705 DLA_02999 F4PJNLW01EE5MJ CDS1138608 2625 - 0.299429
g2720 DLA_03016 F4PJNLW01EE5MJ CDS1170267 1944 + 0.314815
g2739 DLA_03035 F4PJNLW01EE5MJ CDS1213710 1593 + 0.338983
g2797 DLA_03097 F4PJNLW02GJ9ZB CDS85137 2370 - 0.337975
g2816 DLA_03116 similar to eukaryotic translation initiation factor 4A isoform 2 F4PJNLW02GJ9ZB CDS129122 1155 + 0.386147
g2818 DLA_03118 E. coli ATP-dependent DNA helicase RecQ is involved in genome maintenance this is the ortholog of the H. sapiens Werner syndrome protein defects in WRN cause the premature onset of multiple age-related disorders F4PJNLW02GJ9ZB CDS132381 2568 + 0.279595
g2824 DLA_03127 F4PJNLW02GJ9ZB CDS146833 2541 - 0.245179
g2825 DLA_03128 similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases predicted to activate SG2 cyclins cyclin A B and D F4PJNLW02GJ9ZB CDS150193 900 + 0.331111
g2837 DLA_03140 similar to Dna2 a DNA replication factor required for Okazaki fragment processing and involved in DNA repair pathways F4PJNLW02GJ9ZB CDS172310 4101 - 0.292855
g284 DLA_00314 contig05409_1.exp CDS652127 3645 + 0.322908
g2857 DLA_11542 similar to eukaryotic initiation factor 4A isoform 3 F4PJNLW02GJ9ZB CDS228496 1212 + 0.319307
g2874 DLA_03185 F4PJNLW02GJ9ZB CDS270085 927 - 0.316073
g2880 DLA_03192 F4PJNLW02HBBIY CDS4701 1035 - 0.27343
g292 DLA_00324 contig05409_1.exp CDS676113 1521 + 0.293886
g2921 DLA_03236 F4PJNLW02HBBIY CDS97770 1467 - 0.334015
g2922 DLA_03237 F4PJNLW02HBBIY CDS100288 2214 + 0.337398
g2942 DLA_03260 F4PJNLW02HBBIY CDS138381 11952 + 0.347808
g3037 DLA_03363 F4PJNLW02HBBIY CDS366615 2451 - 0.339861
g3060 DLA_03387 F4PJNLW02HBBIY CDS418335 3711 - 0.306656
g3061 DLA_03388 F4PJNLW02HBBIY CDS422744 2760 + 0.350362
g3113 DLA_03447 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW02HBBIY CDS518303 1077 + 0.287837
g3211 DLA_03560 GAOABQK02FWKR3 CDS24327 2148 + 0.293762
g3216 DLA_11554 CK2 family protein kinase a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein GAOABQK02FWKR3 CDS32017 1611 - 0.306021
g3267 DLA_03616 GAOABQK02G6SYV CDS97173 2745 - 0.289982
g3277 DLA_03627 GAOABQK02G6SYV CDS120541 1149 - 0.314186
g3322 DLA_03673 GAOABQK02G6SYV CDS207498 4548 + 0.348505
g3350 DLA_03706 GAOABQK02G6SYV CDS264850 3468 - 0.364475
g3401 DLA_03761 GAOABQK02G6SYV CDS373601 1809 + 0.342731
g3412 DLA_03775 GAOABQK02G6SYV CDS393352 3546 + 0.368302
g3448 DLA_03813 similar to ATP-dependent RNA helicase M NAM7and to putative helicases involved in RNA maturation SEN1 human senataxin imlicated in ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4) also belongs to this family GAOABQK02G6SYV CDS481931 2796 + 0.344778
g3477 DLA_03851 GAOABQK02G6SYV CDS543912 2457 + 0.307692
g3479 DLA_03854 GAOABQK02G6SYV CDS548414 2544 - 0.307783
g3497 DLA_03875 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GAOABQK02G6SYV CDS594795 1926 - 0.339564
g3499 DLA_03877 GAOABQK02G6SYV CDS599757 1542 - 0.328794
g3521 DLA_03898 conserved splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint the human ortholog (BAT1) forms a homodimer and interacts directly with GAOABQK02G6SYV CDS650307 1281 + 0.357533
g3537 DLA_03916 STE SerThr protein kinase family mitogen-activated protein kinase kinase involved in chemotaxis and early development phosphorylates the MAP kinase Erk1 (erkA) is sumoyalated by sumo and ubiquinated by mip1 GAOABQK02G6SYV CDS686979 1284 - 0.323209
g3549 DLA_03930 GAOABQK02G7M1S CDS12808 2847 + 0.334387
g3558 DLA_03938 GAOABQK02G7M1S CDS31797 4113 + 0.292001
g3567 DLA_03951 GAOABQK02G7M1S CDS67898 3429 + 0.345582
g36 DLA_00041 contig05409_1.exp CDS91681 2490 - 0.377108
g3635 DLA_04031 GAOABQK02G7M1S CDS227137 1110 + 0.362162
g3647 DLA_04044 GAOABQK02G7M1S CDS257955 1452 - 0.304408
g3713 DLA_04114 similar to Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) contains one SH3 (src Homology-3) domain GAOABQK02G7M1S CDS413945 2100 + 0.350952
g3725 DLA_04128 GAOABQK02G7M1S CDS436959 2169 - 0.323651
g3741 DLA_04144 GAOABQK02G7M1S CDS471893 2535 - 0.341223
g3784 DLA_04196 GAOABQK02G7M1S CDS566511 1071 + 0.345472
g3799 DLA_04213 GAOABQK02G7M1S CDS604665 1314 + 0.362253
g3807 DLA_04222 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras GAOABQK02G7M1S CDS617133 4275 - 0.349942
g3821 DLA_04239 GAOABQK02G7M1S CDS664421 2448 - 0.319853
g3836 DLA_04254 GAOABQK02G7M1S CDS693478 3450 - 0.325507
g3864 DLA_04284 GAOABQK02G7M1S CDS761256 1530 + 0.336601
g3877 DLA_04298 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family expressed in pstO cells GAOABQK02GQAQJ CDS20246 1581 + 0.31246
g3918 DLA_04343 GAOABQK02GQAQJ CDS111354 2523 - 0.317876
g3923 DLA_04350 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis GAOABQK02GQAQJ CDS129732 1560 + 0.350641
g3926 DLA_04353 GAOABQK02GQAQJ CDS136067 750 + 0.342667
g3934 DLA_04363 GAOABQK02GQAQJ CDS151071 2484 + 0.355878
g3960 DLA_04389 GAOABQK02GQAQJ CDS202770 3390 - 0.314454
g3962 DLA_04391 GAOABQK02GQAQJ CDS209901 624 - 0.355769
g3974 DLA_04404 GAOABQK02GQAQJ CDS230653 6513 + 0.340243
g398 DLA_00442 contig05409_1.exp CDS911085 2340 + 0.334188
g4011 DLA_04450 GAOABQK02GQAQJ CDS329479 546 + 0.358974
g4012 DLA_04451 GAOABQK02GQAQJ CDS330396 939 - 0.342918
g403 DLA_00447 contig05409_1.exp CDS920565 2895 - 0.331606
g4035 DLA_04475 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis GAOABQK02GQAQJ CDS383387 1971 - 0.33587
g4062 DLA_04505 GAOABQK02GQAQJ CDS438051 5988 - 0.305945
g4083 DLA_04526 DEADDEAH box helicases are involved in various aspects of RNA metabolism GAOABQK02GQAQJ CDS483386 2190 - 0.336073
g4149 DLA_04597 GAOABQK02GQAQJ CDS611526 2625 - 0.32419
g4153 DLA_04601 GAOABQK02GQAQJ CDS620307 2193 + 0.367533
g4158 DLA_04605 GAOABQK02GQAQJ CDS630116 7644 + 0.354003
g4163 DLA_04610 GAOABQK02GQAQJ CDS643235 2076 - 0.307803
g4190 DLA_04635 GAOABQK02GQAQJ CDS698291 2691 - 0.302861
g4218 DLA_04665 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases GAOABQK02GQAQJ CDS751139 1023 - 0.362659
g4231 DLA_04678 ortholog of Werner helicase-interacting protein 1 a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis GAOABQK02GQAQJ CDS782385 2436 + 0.309113
g4250 DLA_04697 ortholog of TOP3 a nuclear topoisomerase responsible for relaxing single-stranded negatively-supercoiled DNA GAOABQK02GQAQJ CDS825795 2313 - 0.342412
g4257 DLA_04703 GAOABQK02GQAQJ CDS838889 2607 - 0.322593
g4271 DLA_04716 GAOABQK02GQAQJ CDS869762 8682 - 0.349804
g430 DLA_00477 contig05409_1.exp CDS974153 4065 + 0.327429
g4303 DLA_04749 GAOABQK02GQAQJ CDS952334 1602 + 0.338951
g4324 DLA_04772 GAOABQK02GQAQJ CDS1004164 999 - 0.332332
g4336 DLA_04789 GAOABQK02GQAQJ CDS1046815 4053 + 0.339255
g4349 DLA_04805 GAOABQK02GQAQJ CDS1078207 1833 + 0.26132
g4362 DLA_04821 GAOABQK02GRIAE CDS20539 2247 - 0.315532
g4412 DLA_04878 GAOABQK02GRIAE CDS155358 4623 + 0.307376
g4457 DLA_04936 GAOABQK02H81I9 CDS26587 2580 - 0.312403
g4458 DLA_04937 GAOABQK02H81I9 CDS29274 1683 + 0.322044
g4489 DLA_04970 GAOABQK02H81I9 CDS97703 8262 + 0.26398
g4538 DLA_05029 GAOABQK02H81I9 CDS228244 4599 - 0.346815
g4548 DLA_05040 CK2 family protein kinase a ubiquitious serinethreonine protein kinase in eukaryotic cells that phosphorylates many protein substrates in addition to casein GAOABQK02H81I9 CDS251379 1047 + 0.325692
g4577 DLA_05072 GAOABQK02H81I9 CDS314015 1854 - 0.326321
g4604 DLA_05099 GAOABQK02H81I9 CDS375330 2349 + 0.325671
g4615 DLA_05112 GAOABQK02H81I9 CDS404366 2184 - 0.322344
g4619 DLA_05116 GAOABQK02H81I9 CDS415520 3084 + 0.32393
g4628 DLA_05125 GAOABQK02H81I9 CDS434500 4944 + 0.344053
g4629 DLA_05126 GAOABQK02H81I9 CDS440362 2097 - 0.379113
g4681 DLA_05182 GAOABQK02H81I9 CDS554984 3123 + 0.32789
g4683 DLA_05184 GAOABQK02H81I9 CDS559866 1626 - 0.346248
g4689 DLA_05192 GAOABQK02H81I9 CDS578951 4812 + 0.341854
g4784 DLA_05295 GAOABQK02H81I9 CDS806986 5853 - 0.320178
g4793 DLA_05305 controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands this is predicted to be a nuclear topoisomerase II GAOABQK02H81I9 CDS826964 3756 - 0.305644
g4811 DLA_05328 GAOABQK02H81I9 CDS864922 1761 + 0.284497
g4816 DLA_05332 GAOABQK02H81I9 CDS873335 2250 - 0.326667
g4863 DLA_05385 GAOABQK02HUB3S CDS82935 5202 + 0.328143
g49 DLA_00058 contig05409_1.exp CDS128252 1062 - 0.322034
g4930 DLA_11628 GAOABQK02HUB3S CDS246344 969 + 0.268318
g4991 DLA_05525 GAOABQK02HUB3S CDS383190 1203 - 0.320033
g4993 DLA_05527 GAOABQK02HUB3S CDS385563 792 + 0.305556
g5031 DLA_05571 GAOABQK02HUB3S CDS461404 2952 - 0.32893
g5032 DLA_05572 GAOABQK02HUB3S CDS464705 1032 + 0.319767
g5070 DLA_05615 GAOABQK02HUB3S CDS553749 6030 - 0.315091
g5073 DLA_05618 GAOABQK02HUB3S CDS562805 2460 - 0.314634
g5074 DLA_05619 GAOABQK02HUB3S CDS566617 2586 - 0.317479
g5087 DLA_05635 GAOABQK02HUB3S CDS593660 1707 - 0.313415
g5104 DLA_05653 GAOABQK02HUB3S CDS640198 1047 + 0.295129
g5108 DLA_05657 GAOABQK02HUB3S CDS648858 2475 - 0.298586
g5135 DLA_05687 GAOABQK02HUB3S CDS709936 2475 + 0.30101
g5141 DLA_05701 GAOABQK02HUB3S CDS728826 4296 + 0.30703
g5144 DLA_05704 GAOABQK02HUB3S CDS739651 3900 + 0.332564
g5146 DLA_05706 GAOABQK02HUB3S CDS745347 4065 + 0.342927
g5285 DLA_05866 GAOABQK02HUB3S CDS1120661 2448 - 0.330474
g5310 DLA_05900 GAOABQK02HUB3S CDS1179641 2886 + 0.288635
g5324 DLA_05919 GAOABQK02HUB3S CDS1212357 1665 - 0.306306
g5336 DLA_05934 GAOABQK02HUB3S CDS1241031 3873 + 0.32662
g5344 DLA_05945 GAOABQK02HUB3S CDS1261425 951 + 0.299685
g5374 DLA_05981 ortholog of H. sapiens xeroderma pigmentosum group D (XPD) M. musculus ERCC2 and S. cerevisiae RAD3 GAOABQK02HUB3S CDS1341303 2334 + 0.344045
g5418 DLA_06031 GAOABQK02HUB3S CDS1431770 2691 - 0.353772
g5428 DLA_06042 GAOABQK02HUB3S CDS1453817 2178 + 0.305785
g5445 DLA_06065 GAOABQK02HUB3S CDS1494646 993 + 0.316213
g5448 DLA_06068 GAOABQK02HUB3S CDS1502068 3438 - 0.331006
g5479 DLA_06106 GAOABQK02HUB3S CDS1564607 1050 - 0.340952
g5480 DLA_06107 GAOABQK02HUB3S CDS1565814 2001 + 0.34083
g5538 DLA_06170 GAOABQK02HUB3S CDS1707826 2439 + 0.345223
g56 DLA_00066 contig05409_1.exp CDS143247 2988 - 0.319946
g561 DLA_00617 contig05409_1.exp CDS1280986 912 - 0.358553
g5647 DLA_06294 GAOABQK02IBA3P CDS85170 930 - 0.291398
g565 DLA_00622 contig05409_1.exp CDS1291713 2670 - 0.320225
g5654 DLA_06300 GAOABQK02IBA3P CDS100124 4236 - 0.344901
g5659 DLA_06305 GAOABQK02IBA3P CDS119528 4551 + 0.307185
g5675 DLA_06322 GAOABQK02IBA3P CDS154496 3345 + 0.339611
g5712 DLA_06367 GAOABQK02IBA3P CDS238671 2769 + 0.313109
g5729 DLA_06391 GAOABQK02IBA3P CDS305679 2820 - 0.324823
g5743 DLA_06406 GAOABQK02IBA3P CDS334439 2538 + 0.326241
g5751 DLA_06414 GAOABQK02IBA3P CDS360993 1308 + 0.29052
g5758 DLA_06422 GAOABQK02IBA3P CDS377139 4905 - 0.332518
g5770 DLA_06436 ortholog of the mammalian aquarius (AQR) protein an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis GAOABQK02IBA3P CDS401701 4101 + 0.320897
g5785 DLA_06452 GAOABQK02IBA3P CDS440360 4989 + 0.338144
g5793 DLA_06460 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase GAOABQK02IBA3P CDS453719 2019 - 0.327885
g5833 DLA_06505 GAOABQK02IBA3P CDS533689 4170 - 0.356115
g5842 DLA_06516 GAOABQK02IBA3P CDS553910 3255 - 0.349309
g5889 DLA_06561 GAOABQK02IBA3P CDS655419 3693 - 0.355808
g5922 DLA_06599 GAOABQK02IBA3P CDS753807 4353 + 0.316334
g5959 DLA_11661 GAOABQK02IBA3P CDS839364 762 - 0.368766
g5988 DLA_06668 GAOABQK02IBA3P CDS902080 2700 + 0.346296
g5991 DLA_06672 GAOABQK02IBA3P CDS909843 3057 + 0.298659
g6002 DLA_06684 GAOABQK02IBA3P CDS951201 2358 - 0.337574
g6024 DLA_06711 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains GAOABQK02IBA3P CDS1003562 5019 - 0.328751
g6055 DLA_06742 similar to Dictyostelium pakA and other mitogen-activated protein kinases (Ste20PAK family) putative p21-activated kinase contains a calponin-like actin-binding domain a p21-Rho-binding domain and a PKC conserved region 1 (C1) regulates the actin cytoskeleton response during chemotaxis to cAMP GAOABQK02IBA3P CDS1064531 3954 + 0.309054
g6070 DLA_06756 contains one 5'-3' exonuclease domain and one 3'-5' exonuclease domain GAOABQK02IBA3P CDS1094275 6369 - 0.302245
g6083 DLA_06771 GAOABQK02INHKB CDS9919 3717 - 0.313963
g6136 DLA_06835 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GAOABQK02IO52T CDS102489 4140 - 0.322947
g6149 DLA_06849 GAOABQK02IO52T CDS138582 3204 + 0.334582
g6260 DLA_06974 GAOABQK02IO52T CDS373105 1275 + 0.294902
g6279 DLA_06993 GAOABQK02IO52T CDS413957 3456 - 0.303241
g6286 DLA_07000 ATP-dependent DNA ligase required for the ligation of Okazaki fragments during lagging-strand DNA synthesis GAOABQK02IO52T CDS433888 2760 + 0.334058
g6318 DLA_07037 GAOABQK02IO52T CDS497222 2205 - 0.317914
g6367 DLA_07087 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase GAOABQK02IO52T CDS603199 2982 + 0.346412
g6377 DLA_07097 GAOABQK02IO52T CDS627094 2634 - 0.314351
g6393 DLA_07114 putative protein serinethreonine kinase N-terminus similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase C-terminal half belongs to the peptidase C2 family contains 4 calpain III domains and has similarity to calpain-like cysteine protease GAOABQK02IO52T CDS657826 3318 + 0.347499
g6396 DLA_07117 controls RNA polymerase II activity by phosphorylating the carboxy terminal domain (CTD) of the largest subunit predicted to interact with GAOABQK02IO52T CDS663556 1113 + 0.343217
g6426 DLA_07149 GAOABQK02JBK0O CDS31261 1320 + 0.27197
g6433 DLA_07159 GAOABQK02JBK0O CDS45121 2970 - 0.306734
g6445 DLA_07172 GAOABQK02JBK0O CDS78619 2445 - 0.310429
g6446 DLA_07173 GAOABQK02JBK0O CDS81330 1440 + 0.301389
g6469 DLA_07198 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog GAOABQK02JBK0O CDS135234 3006 - 0.294744
g6497 DLA_07234 GAOABQK02JEBFV CDS45755 2196 - 0.331056
g6524 DLA_07265 GAOABQK02JOCCH CDS48097 3072 + 0.277995
g6529 DLA_07270 GAOABQK02JOCCH CDS58644 1905 - 0.290814
g6568 DLA_07319 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation GAOABQK02JOCCH CDS155446 1314 + 0.350837
g6607 DLA_07358 GAOABQK02JOCCH CDS240004 12681 - 0.328365
g6674 DLA_07435 GAOABQK02JOCCH CDS403183 3987 + 0.346627
g6679 DLA_07439 GAOABQK02JOCCH CDS414241 1386 - 0.368687
g6685 DLA_07445 GAOABQK02JOCCH CDS426048 2004 - 0.313872
g6686 DLA_07446 GAOABQK02JOCCH CDS428514 2859 - 0.317943
g6711 DLA_07474 GAOABQK02JOCCH CDS471109 7059 - 0.374982
g6712 DLA_07475 GAOABQK02JOCCH CDS478671 2856 + 0.290966
g6737 DLA_07503 GAOABQK02JOCCH CDS537620 3087 - 0.308066
g680 DLA_00750 F4PJNLW01A00V1 CDS99661 993 - 0.352467
g6839 DLA_07621 GAOABQK02JOCCH CDS775507 6165 + 0.323114
g6857 DLA_07643 GAOABQK02JOCCH CDS812714 6405 - 0.340515
g6883 DLA_07677 GAOABQK02JOCCH CDS880767 1194 + 0.326633
g6889 DLA_07685 GLQOFTK02FH5TG CDS8846 2778 - 0.302736
g6929 DLA_11693 GLQOFTK02FH5TG CDS95960 2934 + 0.316633
g6942 DLA_07740 putative protein serinethreonine kinase the kinase domain is similar to yeast IRE1 kinase required for inositol phototrophy there is a second copy of this gene GLQOFTK02FH5TG CDS119247 2916 + 0.315844
g6993 DLA_07795 GLQOFTK02FH5TG CDS226617 3459 + 0.33449
g6997 DLA_07799 GLQOFTK02FH5TG CDS238572 1332 - 0.292793
g7011 DLA_07814 GLQOFTK02FH5TG CDS269937 6186 + 0.35257
g7015 DLA_07818 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene GLQOFTK02FH5TG CDS283213 2583 - 0.342238
g7016 DLA_07821 GLQOFTK02FH5TG CDS291583 3063 + 0.316683
g7046 DLA_07859 ortholog of ATP-dependent RNA helicase DDX1 contains an SPRY domain which is of unknown function GLQOFTK02FH5TG CDS370624 3510 + 0.329345
g7047 DLA_07861 ortholog of Rad51 which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3 there is a second copy of this gene GLQOFTK02FH5TG CDS374463 1044 - 0.376437
g7120 DLA_07948 GLQOFTK02FH5TG CDS536331 3279 + 0.351632
g713 DLA_00785 F4PJNLW01A00V1 CDS167363 1281 + 0.323966
g7143 DLA_07973 GLQOFTK02FH5TG CDS580542 771 + 0.325551
g7217 DLA_08053 GLQOFTK02FH5TG CDS742825 5442 - 0.34932
g723 DLA_00796 F4PJNLW01A00V1 CDS190893 4350 + 0.355632
g7231 DLA_08070 GLQOFTK02FH5TG CDS776119 1698 + 0.30742
g726 DLA_00799 DEADDEAH box helicases are involved in various aspects of RNA metabolism F4PJNLW01A00V1 CDS204635 3465 - 0.361039
g7270 DLA_08116 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation GLQOFTK02FH5TG CDS864074 2313 - 0.378729
g7283 DLA_08133 GLQOFTK02FH5TG CDS894541 1524 + 0.324803
g7311 DLA_08167 GLQOFTK02FH5TG CDS950417 6909 - 0.345202
g7334 DLA_08195 GLQOFTK02FH5TG CDS1018729 1275 - 0.337255
g7342 DLA_08206 GLQOFTK02FH5TG CDS1036092 1260 + 0.292064
g7344 DLA_08208 GLQOFTK02FH5TG CDS1039642 2334 - 0.334619
g7357 DLA_08224 STE20PAK protein kinase required for normal chemotaxis contains PAK-boxP21-Rho-binding (CRIB) domain and pleckstrin homology (PH) domain GLQOFTK02FH5TG CDS1063318 1470 + 0.383673
g7376 DLA_08247 GLQOFTK02FH5TG CDS1107166 4839 + 0.356892
g74 DLA_00085 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene contig05409_1.exp CDS177081 1011 - 0.328388
g7419 DLA_08295 GLQOFTK02FH5TG CDS1229535 1950 - 0.351795
g7438 DLA_08319 STE20PAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis contains PAK-boxP21-Rho-binding (CRIB) domain found in the WASP C-terminal GLQOFTK02FH5TG CDS1260149 3315 + 0.355656
g7439 DLA_08320 GLQOFTK02FH5TG CDS1263935 2562 + 0.302888
g7469 DLA_08356 GLQOFTK02FH5TG CDS1335202 1944 - 0.308128
g7472 DLA_08359 ortholog of the DNA primase large subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication GLQOFTK02FH5TG CDS1344065 1356 + 0.314897
g7512 DLA_08407 GLQOFTK02FH5TG CDS1442202 1704 + 0.33216
g7550 DLA_08444 GLQOFTK02FH5TG CDS1515984 2223 + 0.253261
g7661 DLA_08565 GLQOFTK02G2F2O CDS220668 1914 - 0.367816
g7666 DLA_08571 GLQOFTK02G2F2O CDS229400 3729 + 0.335747
g769 DLA_00847 F4PJNLW01A00V1 CDS288983 5649 + 0.355815
g7696 DLA_08609 controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands this is predicted to be a nuclear topoisomerase II GLQOFTK02G2F2O CDS317745 4539 - 0.352941
g7724 DLA_08642 GLQOFTK02G2F2O CDS383694 4512 - 0.359043
g7744 DLA_08659 GLQOFTK02G2F2O CDS430417 1089 - 0.337006
g7760 DLA_08678 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog GLQOFTK02G2F2O CDS466621 3690 - 0.304336
g7766 DLA_08684 member of the TKL (tyrosine kinase-like) group of protein kinases contains filamin repeat similar to ABP120 GLQOFTK02G2F2O CDS482933 4218 + 0.336415
g7774 DLA_08691 GLQOFTK02G2F2O CDS496310 2664 - 0.311937
g7784 DLA_08700 putative protein serinethreonine kinase similar to yeast CDC5 Drosophila polo and mammalian PLK which play a role in mitosis and localize to the centrosomes GLQOFTK02G2F2O CDS522616 2478 - 0.315174
g7798 DLA_08718 GLQOFTK02G2F2O CDS553106 5211 - 0.333525
g7839 DLA_08763 SNF2 family protein similar to human SMARCA4 putative regulator of chromatin GLQOFTK02G2F2O CDS635822 6768 + 0.346927
g7892 DLA_08825 GLQOFTK02G2F2O CDS749498 1536 + 0.326172
g7909 DLA_08843 GLQOFTK02G2F2O CDS779995 1656 + 0.300121
g7916 DLA_08851 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene GLQOFTK02G2F2O CDS793088 993 - 0.293051
g7923 DLA_08857 GLQOFTK02G2F2O CDS804563 1752 + 0.304224
g7953 DLA_08888 GLQOFTK02G2F2O CDS886835 1737 + 0.35118
g7959 DLA_08894 similar to metazoan cyclin H predicted to interact with cyclin-dependent kinase GLQOFTK02G2F2O CDS898007 1032 + 0.297481
g8026 DLA_08974 similar to metazoan cyclin C predicted to interact with cyclin-dependent kinase GLQOFTK02G2F2O CDS1043323 768 + 0.303385
g8047 DLA_08996 GLQOFTK02G2F2O CDS1097062 1173 + 0.337596
g8060 DLA_09009 GLQOFTK02G2F2O CDS1125492 2442 + 0.320639
g8072 DLA_09022 GLQOFTK02G2F2O CDS1157651 3978 + 0.302916
g8077 DLA_09028 GLQOFTK02G2F2O CDS1171541 1416 + 0.336158
g8100 DLA_09053 GLQOFTK02G2F2O CDS1221193 1047 - 0.282713
g8111 DLA_09065 GLQOFTK02G2F2O CDS1252809 5997 + 0.31399
g8123 DLA_09078 GLQOFTK02G2F2O CDS1290791 1539 + 0.345679
g82 DLA_00094 contig05409_1.exp CDS186440 2235 - 0.365101
g8213 DLA_09170 protein serinethreonine kinase GSK family member of the CMGC kinase group essential for cell specification activated by CAR3 through ZAK1 (prespore-) and inhibited by CAR4 (prestalk-) signalling GLQOFTK02G2F2O CDS1477962 1386 - 0.330447
g8218 DLA_09175 GLQOFTK02G2F2O CDS1490003 1221 - 0.329238
g8250 DLA_09212 GLQOFTK02G2F2O CDS1568149 1248 + 0.334135
g8258 DLA_09218 GLQOFTK02G2F2O CDS1580676 4380 - 0.324886
g8261 DLA_09221 GLQOFTK02G2F2O CDS1591695 1860 + 0.374731
g8273 DLA_09234 GLQOFTK02G2F2O CDS1617316 1968 + 0.303862
g8277 DLA_11766 GLQOFTK02G2F2O CDS1623178 1323 - 0.284958
g8280 DLA_09241 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family contains a C2 domain (Ca2-dependent membrane-targeting module) an ankyrin repeat region and a SAM (Sterile alpha motif) domain GLQOFTK02G2F2O CDS1628524 2817 + 0.334398
g829 DLA_00909 F4PJNLW01A00V1 CDS409957 3246 + 0.379544
g8296 DLA_09257 GLQOFTK02G2F2O CDS1667785 3975 + 0.318239
g832 DLA_00912 similar to the cell division cycle 2-related protein kinase 7 (CRK7) and other cell division cycle 2-like protein kinases there is a second copy of this gene F4PJNLW01A00V1 CDS418405 1833 + 0.355701
g835 DLA_00916 F4PJNLW01A00V1 CDS428746 1794 - 0.375697
g8370 DLA_09336 GLQOFTK02G2F2O CDS1806183 2058 + 0.31827
g8420 DLA_09390 the kinase domain is similar to mammalian stress-induced STK and OSR1 (oxidative stress responsive 1) kinases and other STE20-like kinasesbrbr bCommunity annotation:b Fray1 and Fray2 represent the FRAY-subfamily of Ste20-like kinases in D. discoideum (see GLQOFTK02G2F2O CDS1897895 3102 + 0.356222
g8442 DLA_09414 GLQOFTK02G2F2O CDS1944715 3000 - 0.352333
g8505 DLA_09482 ortholog of H. sapiens DDX52 and S. cerevisiae ROK1 (Rescuer Of Kem1) ROK1 required for 18S rRNA synthesis GLQOFTK02GHM7A CDS33431 1893 - 0.277866
g8509 DLA_09485 GLQOFTK02GHM7A CDS40990 7914 + 0.321203
g8519 DLA_09495 GLQOFTK02GHM7A CDS67461 948 + 0.291139
g8522 DLA_09499 putative protein serinethreonine kinase similar to the kinase domains of AAK1 (AP2 associated kinase) and BMP-inducible protein kinase (BIKe) GLQOFTK02GHM7A CDS76238 2130 + 0.302817
g855 DLA_00935 F4PJNLW01A00V1 CDS483602 570 + 0.308772
g8564 DLA_09547 GLQOFTK02GHM7A CDS162001 3615 + 0.333333
g857 DLA_00937 F4PJNLW01A00V1 CDS487333 2793 + 0.368779
g8571 DLA_09556 DEADDEAH box helicases are involved in various aspects of RNA metabolism GLQOFTK02GHM7A CDS179980 3096 + 0.347222
g8572 DLA_09557 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog GLQOFTK02GHM7A CDS183164 2592 - 0.297839
g8593 DLA_09585 GLQOFTK02GHM7A CDS246755 4185 + 0.314934
g8597 DLA_09589 GLQOFTK02GHM7A CDS256496 2496 - 0.306891
g8633 DLA_09626 GLQOFTK02GHM7A CDS349150 3288 - 0.327251
g8656 DLA_09651 similar to CDK1 and CDK2 cell cycle CAK (CDK-activating kinase) kinases predicted to activate SG2 cyclins cyclin A B and D GLQOFTK02GHM7A CDS398221 876 - 0.381279
g8695 DLA_09691 GLQOFTK02GHM7A CDS481830 1944 - 0.360082
g873 DLA_00957 ortholog of MYH which removes misincorporated adenine residues opposite template 8-oxoguanine during DNA replication F4PJNLW01A00V1 CDS536344 1554 - 0.301158
g8754 DLA_09749 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase GLQOFTK02GHM7A CDS614852 1455 - 0.364948
g8760 DLA_09756 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation GLQOFTK02GHM7A CDS625916 2046 - 0.351417
g8847 DLA_09849 putative protein serinethreonine kinase similar to vertebrate Nek kinases which are involved in regulation of mitosis not a human Nek3 homolog GLQOFTK02GHM7A CDS851623 2403 + 0.293383
g8857 DLA_09861 GLQOFTK02GHM7A CDS872304 1011 - 0.302671
g8869 DLA_09883 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases belongs to the PAKL subfamilystress-responsive kinase there is a second copy of this gene GLQOFTK02GQ36N CDS17991 1569 - 0.297642
g8880 DLA_09895 GLQOFTK02GQ36N CDS37449 2145 + 0.327273
g8900 DLA_09918 GLQOFTK02GQ36N CDS86387 2031 - 0.293451
g8906 DLA_09925 GLQOFTK02GQ36N CDS97926 1716 - 0.327506
g8919 DLA_09938 GLQOFTK02GQ36N CDS132556 7536 + 0.348726
g8941 DLA_09960 GLQOFTK02GQ36N CDS186083 1941 - 0.325605
g8961 DLA_09982 ortholog of the yeast IRE1 serinethreonine kinaseendoribonuclease a transmembrane protein involved in the unfolded protein response contains a ribonuclease 2-5A domain and 3 pyrrolo-quinoline quinone (PQQ) domains GLQOFTK02GQ36N CDS225395 3168 - 0.322285
g8978 DLA_10001 GLQOFTK02GQ36N CDS265383 3807 - 0.321513
g8980 DLA_10003 GLQOFTK02GQ36N CDS270268 1119 + 0.302949
g9002 DLA_10025 GLQOFTK02GQ36N CDS315308 3954 - 0.321194
g9035 DLA_10056 GLQOFTK02GQ36N CDS377200 1983 + 0.33535
g9098 DLA_10129 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras GLQOFTK02GQ36N CDS538065 4770 - 0.341719
g9105 DLA_10135 GLQOFTK02GQ36N CDS559750 1464 - 0.303962
g9122 DLA_10157 GLQOFTK02GQ36N CDS599686 3750 - 0.333067
g9152 DLA_10193 protein serinethreonine kinase CK1 family similar to human CK1 and yeast YCK may play a role in DNA repair there is a second copy of this gene GLQOFTK02GQ36N CDS660860 1158 - 0.325561
g9210 DLA_10261 GLQOFTK02GUKFG CDS129499 4644 + 0.343239
g922 DLA_01020 F4PJNLW01A00V1 CDS643466 2934 + 0.308453
g9266 DLA_10324 GLQOFTK02GUKFG CDS265535 5454 + 0.351485
g9282 DLA_10341 GLQOFTK02GUKFG CDS315277 1017 + 0.365782
g931 DLA_01031 F4PJNLW01A00V1 CDS661501 4101 + 0.333821
g9331 DLA_10402 GLQOFTK02GUKFG CDS414480 5160 - 0.312403
g9377 DLA_10448 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteinsbrbr bCommunity annotation:b The five fhk-X genes differ substantially in their response to the disruption of the retinoblastoma-like gene rblA. FhkA is substantially and highly signficantly upregulated in the ko strain while none of the other genes show major changes. Consistent with its regulation the fhkA promoter contains a putative E2F-type binding site (TTTGCGCCTTTT). Virtually all genes associated with replication fork progression are upregulated in the rblA disruptant these include cdc45 all mcm genes all gins genes all rfc genes four polA subunits three polD subunits two putatitive polE subunits PCNA the single-strand binding protein rfa1 the flap endonuclease repG as well as DNA ligase-1 and topoisomerase-2. All these genes show overexpression factors ranging from 4 to 15 GLQOFTK02GUKFG CDS509525 1584 - 0.297348
g9430 DLA_10507 GLQOFTK02IIOHN CDS50069 675 - 0.284444
g9445 DLA_10523 GLQOFTK02IIOHN CDS85920 4386 + 0.332421
g9459 DLA_10543 GLQOFTK02IIOHN CDS118203 1749 - 0.277301
g9463 DLA_10547 GLQOFTK02IIOHN CDS125810 2967 - 0.290529
g9485 DLA_10572 GLQOFTK02IJPNF CDS8032 1290 + 0.285271
g9529 DLA_10621 similar to eukaryotic initiation factor 4A isoform 3 GLQOFTK02IJPNF CDS114540 1242 + 0.36715
g959 DLA_01062 F4PJNLW01A00V1 CDS726650 957 + 0.289446
g9617 DLA_10723 GLQOFTK02IRMR1 CDS31401 4668 - 0.336118
g963 DLA_01066 F4PJNLW01A00V1 CDS736130 7947 - 0.317227
g9636 DLA_10743 GLQOFTK02IRMR1 CDS81280 1392 - 0.333333
g9648 DLA_10760 GLQOFTK02IRMR1 CDS111344 1833 - 0.346972
g9654 DLA_10766 GLQOFTK02IRMR1 CDS123810 3429 + 0.314669
g9690 DLA_10814 GLQOFTK02JCFFB CDS3414 2112 + 0.297822
g9711 DLA_10837 plays a role in the regulation of cleavage furrow formation similar to S. pombe cdc7 GLQOFTK02JCFFB CDS55659 3321 + 0.350196
g9730 DLA_10862 GLQOFTK02JCFFB CDS106430 2298 - 0.295909
g9754 DLA_10889 GLQOFTK02JL55Q CDS43907 2400 - 0.28625
g977 DLA_01087 F4PJNLW01A00V1 CDS776180 2457 - 0.293447
g9859 DLA_11004 GLQOFTK02JL55Q CDS280021 1545 - 0.374757
g9870 DLA_11015 GLQOFTK02JL55Q CDS307354 3702 + 0.337655
g9891 DLA_11039 GLQOFTK02JL55Q CDS354517 1455 - 0.318213
g990 DLA_01099 F4PJNLW01A00V1 CDS804435 1251 - 0.311751
g9911 DLA_11059 GLQOFTK02JL55Q CDS397671 1128 + 0.350177
g9965 DLA_11115 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis GLQOFTK02JL55Q CDS530149 2103 + 0.32525
g9972 DLA_11125 GLQOFTK02JL55Q CDS541515 867 + 0.322953
g9996 DLA_11151 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family contains RasGEF nucleotide exchange factor domain GLQOFTK02JL55Q CDS582167 2604 + 0.355607
 
Polysphondylium pallidum, PN500
NameLocus tagProduct / DescriptionUniProt / TrEMBL protein nameGenomic elementTypeBeginLengthStrandGC-content
g10019 PPL_10545 EXOLTKG01B86TH-3_part2 CDS361931 4890 - 0.358896
g1003 PPL_01166 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation DPPA0061d07.r1-5 CDS868162 1338 - 0.443199
g10033 PPL_10562 similar to MCM4 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex EXOLTKG01B86TH-3_part2 CDS435121 2724 + 0.4163
g10061 PPL_10592 EXOLTKG01B86TH-3_part2 CDS509293 2106 + 0.390788
g10119 PPL_10649 EXOLTKG01B86TH-3_part2 CDS672884 2379 + 0.374527
g10149 PPL_10678 EXOLTKG01B86TH-3_part2 CDS765097 2415 + 0.392961
g10191 PPL_10728 EXOLTKG01B86TH-3_part2 CDS925365 3426 + 0.3885
g102 PPL_00198 DPPA0004F08.r1-5_part2 CDS293039 3615 - 0.449239
g10216 PPL_13600 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases EXOLTKG01B86TH-3y_part1 CDS56852 1017 + 0.420846
g10229 PPL_10769 ortholog of TOP3 a nuclear topoisomerase responsible for relaxing single-stranded negatively-supercoiled DNA EXOLTKG01B86TH-3y_part1 CDS97891 2331 - 0.411411
g10300 PPL_10854 putative protein serinethreonine kinase belongs to the PAKL subfamily of protein kinases the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase EXOLTKG01B86TH-3y_part1 CDS339400 2817 + 0.43557
g10303 PPL_10857 EXOLTKG01B86TH-3y_part1 CDS346255 2988 - 0.380522
g10348 PPL_10898 EXOLTKG01B86TH-3y_part1 CDS440642 429 - 0.398601
g10352 PPL_10903 EXOLTKG01B86TH-3y_part2 CDS1862 489 - 0.368098
g10375 PPL_10931 EXOLTKG01B86TH-3y_part2 CDS53266 2256 - 0.477837
g10384 PPL_10941 EXOLTKG01B86TH-3y_part2 CDS72322 1221 - 0.366093
g10400 PPL_10960 EXOLTKG02GJRTE-5 CDS14264 2373 - 0.46397
g1044 PPL_01214 member of the TKL (tyrosine kinase-like) group of protein kinases contains a PH (pleckstrin homology) domain DPPA0061d07.r1-5 CDS982745 3405 - 0.416446
g10472 PPL_11045 EXOLTKG02GJRTE-5 CDS230592 3909 + 0.41494
g10479 PPL_11056 EXOLTKG02GJRTE-5 CDS262251 2529 + 0.441281
g10504 PPL_11085 STE20PAK protein kinase required for normal chemotaxis contains PAK-boxP21-Rho-binding (CRIB) domain and pleckstrin homology (PH) domain EXOLTKG02GJRTE-5 CDS325437 1443 + 0.408177
g1051 PPL_01222 DPPA0061d07.r1-5 CDS1008746 1185 + 0.364557
g10525 PPL_11105 EXOLTKG02GJRTE-5 CDS368020 774 + 0.44832
g10544 PPL_11125 EXOLTKG02GJRTE-5 CDS424144 5184 + 0.376543
g10558 PPL_11139 EXOLTKG02GJRTE-5 CDS455963 3222 - 0.335816
g10569 PPL_11152 PN500-F-W-a08d11.p658-5_part2 CDS22229 2328 - 0.342784
g10597 PPL_11181 PN500-F-W-a08d11.p658-5_part2 CDS93361 3369 - 0.399525
g10643 PPL_11229 PN500-F-W-a08d11.p658-5_part2 CDS213021 7863 + 0.389419
g10684 PPL_11275 there is a second copy of this gene PN500-F-W-a08d11.p658-5_part2 CDS326246 1644 + 0.358881
g10729 PPL_11322 PN500-F-W-a08d11.p658-5_part2 CDS460853 2001 - 0.333833
g10733 PPL_11326 PN500-F-W-a08d11.p658-5_part2 CDS472842 1842 - 0.33279
g10781 PPL_11375 PN500-F-W-a08d11.p658-5_part2 CDS624093 2670 + 0.369288
g10796 PPL_11386 PN500-F-W-a08d11.p658-5_part2 CDS680228 1542 - 0.440986
g10800 PPL_11390 PN500-F-W-a08d11.p658-5_part2 CDS688992 2886 + 0.363825
g1082 PPL_01255 DPPA0061d07.r1-5 CDS1094281 5835 + 0.420566
g10849 PPL_11441 DEADDEAH box helicases are involved in various aspects of RNA metabolism PN500-F-W-a08d11.p658-5_part2 CDS814262 2061 - 0.458515
g10877 PPL_11479 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family contains RasGEF nucleotide exchange factor domain PN500-F-W-a08d11.p658-5_part2 CDS891406 2490 - 0.437751
g10887 PPL_13655 PN500-F-W-a08d11.p658-5_part2 CDS935102 4065 - 0.323493
g10891 PPL_11496 PN500-F-W-a08d11.p658-5_part2 CDS953048 1464 + 0.339481
g11008 PPL_11755 PN500-G-d-72b01.r1-5 CDS49110 1995 + 0.366416
g11019 PPL_11770 PN500-G-d-72b01.r1-5 CDS85196 3249 + 0.341644
g11047 PPL_11799 PN500-G-d-72b01.r1-5 CDS173824 4362 + 0.392481
g11057 PPL_11812 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases PN500-G-d-72b01.r1-5 CDS207838 864 - 0.474537
g11060 PPL_13669 PN500-G-d-72b01.r1-5 CDS219416 3813 + 0.39208
g11095 PPL_11849 PN500-G-d-72b01.r1-5 CDS320547 8007 + 0.432247
g11126 PPL_11880 ATP-dependent DNA ligase required for the ligation of Okazaki fragments during lagging-strand DNA synthesis PN500-G-d-72b01.r1-5 CDS405003 3198 - 0.390557
g1114 PPL_01294 controls RNA polymerase II activity by phosphorylating the carboxy terminal domain (CTD) of the largest subunit predicted to interact with DPPA0061d07.r1-5 CDS1194157 1323 - 0.38322
g11144 PPL_11901 PN500-G-d-72b01.r1-5 CDS458982 4071 - 0.384426
g11148 PPL_11906 protein serinethreonine kinase homologous to human Nek2 kinase involved in formation of microtubule-organizing centers (MTOCs) PN500-G-d-72b01.r1-5 CDS475899 1191 - 0.375315
g11162 PPL_11921 PN500-G-d-72b01.r1-5 CDS512132 1776 + 0.333333
g11180 PPL_11937 PN500-G-d-72b01.r1-5 CDS557050 2781 + 0.419993
g11187 PPL_11946 PN500-G-d-72b01.r1-5 CDS576172 660 + 0.351515
g11230 PPL_11985 PN500-G-d-72b01.r1-5 CDS684282 4011 + 0.373972
g11241 PPL_11996 similar to MCM6 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex PN500-G-d-72b01.r1-5 CDS713640 3201 + 0.434239
g11260 PPL_12018 PN500-G-d-72b01.r1-5 CDS763079 2640 - 0.338258
g11277 PPL_11535 PN500-G-d-156g04.f1-5 CDS16683 2685 + 0.35121
g113 PPL_00209 DPPA0004F08.r1-5_part2 CDS324811 4428 - 0.332656
g11306 PPL_11572 PN500-G-d-188d09.r1-5 CDS73043 2955 - 0.464636
g11308 PPL_11574 PN500-G-d-188d09.r1-5 CDS78956 2478 - 0.316788
g11323 PPL_11588 PN500-G-d-188d09.r1-5 CDS114706 2325 - 0.39914
g11343 PPL_11613 PN500-G-d-188d09.r1-5 CDS175415 1671 - 0.302813
g11358 PPL_11644 PN500-G-d-188d09.r1-5 CDS240318 1884 - 0.293524
g11364 PPL_11658 PN500-G-d-188d09.r1-5 CDS268210 6447 - 0.438033
g1141 PPL_01329 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis DPPA0061d07.r1-5 CDS1275257 1980 - 0.360606
g11438 PPL_00066 contig_new08661_1.exp-5 CDS191659 2007 - 0.38565
g1145 PPL_01333 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras DPPA0061d07.r1-5 CDS1285022 4272 - 0.422285
g1192 PPL_01399 DPPA0090b03.f1-3_x_part2 CDS12953 4380 + 0.4
g1193 PPL_01400 DPPA0090b03.f1-3_x_part2 CDS18179 4233 + 0.381999
g1231 PPL_12786 DPPA0090b03.f1-3_x_part2 CDS128089 501 - 0.353293
g1243 PPL_01452 DPPA0090b03.f1-3_x_part2 CDS162874 2643 - 0.398411
g1262 PPL_01472 similar to S. cerevisiae RAD50 involved in processing double-strand DNA breaks with Mre11 in other organisms Rad50 is part of a complex with Mre11 and Nbs1 no Nbs1 ortholog has been found in Dictyostelium DPPA0090b03.f1-3_x_part2 CDS236546 3906 + 0.426523
g127 PPL_00226 member of the TKL (tyrosine kinase-like) group and the LISK (LIM domain and testis-specific kinase) family expressed in pstO cells DPPA0004F08.r1-5_part2 CDS362759 1659 + 0.356841
g1290 PPL_01501 DPPA0090b03.f1-3_x_part2 CDS315461 948 - 0.397679
g1305 PPL_01514 DPPA0090b03.f1-3_x_part2 CDS354016 972 + 0.435185
g1310 PPL_01520 similar to S. cerevisiae MRE11 involved in processing double-strand DNA breaks with Rad50 in other organisms Mre11 is part of a complex with Rad50 and Nbs1 no Nbs1 ortholog has been found in Dictyostelium DPPA0090b03.f1-3_x_part2 CDS371910 2199 - 0.390177
g1315 PPL_01525 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene DPPA0090b03.f1-3_x_part3 CDS7756 3852 + 0.422378
g137 PPL_00239 DPPA0004F08.r1-5_part2 CDS387062 1278 - 0.327856
g138 PPL_00240 DEADDEAH box helicases are involved in various aspects of RNA metabolism DPPA0004F08.r1-5_part2 CDS388630 2151 - 0.403533
g1382 PPL_01595 DPPA0090b03.f1-3_x_part3 CDS188898 1332 + 0.453453
g1429 PPL_01646 DPPA0090b03.f1-3_x_part3 CDS323827 1998 - 0.424925
g1439 PPL_01659 similar to eukaryotic initiation factor 4A isoform 3 DPPA0090b03.f1-3_x_part3 CDS357426 1407 - 0.380952
g1532 PPL_01763 DPPA0090b03.f1-3_x_part3 CDS625126 621 + 0.301127
g1582 PPL_12839 DPPA0090b03.f1-3_x_part3 CDS758804 1047 - 0.373448
g1604 PPL_01837 DPPA0090b03.f1-3_x_part3 CDS810653 1770 + 0.426554
g1612 PPL_01846 DPPA0090b03.f1-3_x_part3 CDS830830 2520 - 0.380159
g1619 PPL_01855 DPPA0090b03.f1-3_x_part3 CDS867902 645 + 0.382946
g1669 PPL_01909 ortholog of the mammalian aquarius (AQR) protein an intron-binding spliceosomal protein required to link pre-mRNA splicing and snoRNP (small nucleolar ribonucleoprotein) biogenesis DPPA0090b03.f1-3_x_part3 CDS979512 4464 + 0.41353
g1680 PPL_12855 DPPA0090b03.f1-3_x_part3 CDS1005943 3348 - 0.424432
g1699 PPL_01938 DPPA0090b03.f1-3_x_part3 CDS1056906 4815 + 0.394393
g1734 PPL_01971 DPPA0090b03.f1-3_x_part3 CDS1163912 4917 + 0.425259
g1757 PPL_01996 DPPA0090b03.f1-3_x_part3 CDS1235444 3225 + 0.377984
g1784 PPL_12875 DPPA0090b03.f1-3_x_part3 CDS1316369 2463 - 0.457166
g1795 PPL_02039 DPPA0090b03.f1-3_x_part3 CDS1343349 1623 - 0.449168
g1826 PPL_02070 DPPA0090b03.f1-3_x_part3 CDS1434052 939 - 0.362087
g1835 PPL_02081 DPPA0090b03.f1-3_x_part3 CDS1454650 2280 - 0.402193
g1900 PPL_02156 DPPA0090b03.f1-3_x_part3 CDS1679787 1551 + 0.428756
g1915 PPL_12894 ortholog of MYH which removes misincorporated adenine residues opposite template 8-oxoguanine during DNA replication DPPA0090b03.f1-3_x_part3 CDS1723313 1557 - 0.364804
g1939 PPL_02198 DPPA0090b03.f1-3_x_part3 CDS1799831 4131 + 0.384168
g1942 PPL_02201 chromatin remodeling complex subunit R (CHR) protein SWI2SNF2 homolog DPPA0090b03.f1-3_x_part3 CDS1812812 7248 - 0.459299
g1954 PPL_02214 DPPA0090b03.f1-3_x_part3 CDS1847672 1959 + 0.443594
g1957 PPL_12897 DPPA0090b03.f1-3_x_part3 CDS1853947 2934 - 0.423313
g1985 PPL_02243 DPPA0090b03.f1-3_x_part3 CDS1927047 3198 - 0.449343
g1996 PPL_02253 putative protein serinethreonine kinase GSK family member of the CMGC kinase group similar to Drosophila shaggy and other glycogen synthase kinases DPPA0090b03.f1-3_x_part3 CDS1957737 1422 - 0.388186
g2 PPL_00073 DPPA0004F08.r1-5_part2 CDS4871 1854 - 0.306904
g203 PPL_00308 DPPA0004F08.r1-5_part2 CDS571322 4485 + 0.439465
g2042 PPL_02305 DPPA0090b03.f1-3_x_part3 CDS2087083 3243 - 0.310515
g2079 PPL_02348 DPPA0090b03.f1-3_x_part3 CDS2206620 1485 - 0.33266
g2082 PPL_02351 DPPA0090b03.f1-3_x_part3 CDS2216937 5223 - 0.365882
g2086 PPL_02356 DPPA0090b03.f1-3_x_part3 CDS2231539 2316 + 0.408895
g2131 PPL_02405 DPPA0090b03.f1-3_x_part3 CDS2352203 972 - 0.337449
g2161 PPL_02443 DPPA0090b03.f1-3_x_part4 CDS944 1362 - 0.414097
g2168 PPL_02451 ortholog of yeast NAM7 and the mammalian UPF1 (up-frameshift suppressor 1) or RENT1 protein part of a post-splicing multiprotein complex and involved in nonsense-mediated decay (NMD) of mRNAs containing premature stop codons DPPA0090b03.f1-3_x_part4 CDS21186 3342 + 0.467684
g22 PPL_00102 DPPA0004F08.r1-5_part2 CDS58453 6327 - 0.420895
g2209 PPL_02496 DPPA0090b03.f1-3_x_part4 CDS140017 1029 - 0.390671
g2226 PPL_02520 protein serinethreonine kinase GSK family member of the CMGC kinase group essential for cell specification activated by CAR3 through ZAK1 (prespore-) and inhibited by CAR4 (prestalk-) signalling DPPA0090b03.f1-3_x_part4 CDS193844 843 + 0.461447
g2228 PPL_02524 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family contains a C2 domain (Ca2-dependent membrane-targeting module) an ankyrin repeat region and a SAM (Sterile alpha motif) domain DPPA0090b03.f1-3_x_part4 CDS199058 2769 + 0.395811
g2250 PPL_02550 DPPA0090b03.f1-3_x_part4 CDS252587 1464 - 0.299863
g2295 PPL_02604 ortholog of human SKIV2L2 (SuperKIller Viralicitic 2L2) protein and yeast MTR4 a helicase required for mRNA export from the nucleus DPPA0090b03.f1-3_y_part1 CDS82775 3273 - 0.438436
g2316 PPL_02627 DPPA0090b03.f1-3_y_part1 CDS146893 2199 - 0.396544
g2403 PPL_02709 DPPA0090b03.f1-3_y_part1 CDS352780 1998 - 0.296296
g2410 PPL_02717 DPPA0090b03.f1-3_y_part1 CDS369583 2805 + 0.420321
g2416 PPL_02726 ortholog of H. sapiens DDX52 and S. cerevisiae ROK1 (Rescuer Of Kem1) ROK1 required for 18S rRNA synthesis DPPA0090b03.f1-3_y_part1 CDS392904 2115 - 0.344208
g2423 PPL_02732 DPPA0090b03.f1-3_y_part1 CDS409589 2904 + 0.393939
g2517 PPL_02838 DPPA0090b03.f1-3_y_part1 CDS678602 1671 + 0.394973
g253 PPL_00361 DPPA0004F08.r1-5_part2 CDS742518 483 - 0.356108
g2545 PPL_12967 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases DPPA0090b03.f1-3_y_part1 CDS740375 1437 - 0.346555
g2553 PPL_02871 DPPA0090b03.f1-3_y_part1 CDS755019 1053 - 0.349478
g2571 PPL_02893 DPPA0090b03.f1-3_y_part1 CDS801659 3210 - 0.446106
g2580 PPL_02903 similar to Dictyostelium mkcA and mkcB and other mitogen-activated protein kinases (Ste20PAK family) contains one SH3 (src Homology-3) domain DPPA0090b03.f1-3_y_part1 CDS823152 1956 - 0.407975
g2732 PPL_03077 DPPA0090b03.f1-3_y_part1 CDS1264105 1530 + 0.40915
g2744 PPL_03090 DPPA0090b03.f1-3_y_part1 CDS1291592 1074 + 0.393855
g2767 PPL_03116 DPPA0090b03.f1-3_y_part1 CDS1369595 1584 - 0.339015
g2796 PPL_12986 DPPA0090b03.f1-3_y_part1 CDS1451223 1581 + 0.362429
g2822 PPL_03175 DPPA0090b03.f1-3_y_part1 CDS1515496 1089 + 0.413223
g283 PPL_00392 DPPA0004F08.r1-5_part2 CDS822919 1758 - 0.393629
g2838 PPL_03192 DPPA0090b03.f1-3_y_part1 CDS1553911 1041 + 0.384246
g2839 PPL_03193 DPPA0090b03.f1-3_y_part1 CDS1558528 1224 - 0.396242
g2843 PPL_12994 DPPA0090b03.f1-3_y_part1 CDS1574087 2808 + 0.387108
g2857 PPL_03213 DPPA0090b03.f1-3_y_part1 CDS1610971 3087 - 0.407515
g2918 PPL_03275 DPPA0090b03.f1-3_y_part1 CDS1766927 2127 - 0.345087
g2919 PPL_03276 DPPA0090b03.f1-3_y_part1 CDS1769984 2937 - 0.356486
g2946 PPL_03306 DPPA0090b03.f1-3_y_part1 CDS1848960 4065 - 0.382534
g2950 PPL_03310 DPPA0090b03.f1-3_y_part1 CDS1861883 2454 - 0.342706
g2966 PPL_03332 DPPA0090b03.f1-3_y_part1 CDS1901768 1152 - 0.309028
g2993 PPL_03357 DPPA0090b03.f1-3_y_part1 CDS1966455 4686 + 0.364063
g3000 PPL_03365 DPPA0090b03.f1-3_y_part1 CDS1987603 5853 + 0.397232
g3016 PPL_03385 DPPA0090b03.f1-3_y_part1 CDS2036941 3804 + 0.309674
g3017 PPL_03386 DPPA0090b03.f1-3_y_part1 CDS2041368 3852 - 0.371755
g3067 PPL_13024 putative RNA helicase contains an RWD domain (RING finger and WD repeat) DPPA0090b03.f1-3_y_part1 CDS2161133 3852 + 0.400831
g3082 PPL_03458 DPPA0090b03.f1-3_y_part1 CDS2210743 1293 - 0.355762
g3089 PPL_03467 kinase domain similar to S. pombe cdc7 cell division control protein 7 which plays a role in cytokinesis DPPA0090b03.f1-3_y_part1 CDS2231014 1407 - 0.455579
g3185 PPL_03607 DPPA0255d09.f1-5 CDS164765 3828 + 0.434431
g3192 PPL_03616 DPPA0255d09.f1-5 CDS197881 2697 - 0.394512
g3200 PPL_03625 DPPA0255d09.f1-5 CDS219757 1542 - 0.385214
g3206 PPL_03631 similar to Dictyostelium pakA and other mitogen-activated protein kinases (Ste20PAK family) putative p21-activated kinase contains a calponin-like actin-binding domain a p21-Rho-binding domain and a PKC conserved region 1 (C1) regulates the actin cytoskeleton response during chemotaxis to cAMP DPPA0255d09.f1-5 CDS233373 3897 - 0.370028
g321 PPL_00433 DPPA0004F08.r1-5_part2 CDS927334 2187 + 0.404664
g3213 PPL_03643 DPPB0337b12.r1-5 CDS1815 2769 - 0.376309
g3235 PPL_03671 DPPB0337b12.r1-5 CDS63721 2886 + 0.341303
g3237 PPL_03674 DPPB0337b12.r1-5 CDS68868 2373 - 0.435314
g3251 PPL_03689 DPPB0337b12.r1-5 CDS106227 2013 - 0.448087
g3264 PPL_03704 DEADDEAH box helicases are involved in various aspects of RNA metabolism DPPB0337b12.r1-5 CDS149662 3294 - 0.390407
g3284 PPL_03723 CAMK group RAD53 family protein kinase similar to mammalian cell cycle checkpoint kinases chk2 contains a forkhead-associated (FHA) domain a phosphopeptide recognition domain found in many regulatory proteinsbrbr bCommunity annotation:b The five fhk-X genes differ substantially in their response to the disruption of the retinoblastoma-like gene rblA. FhkA is substantially and highly signficantly upregulated in the ko strain while none of the other genes show major changes. Consistent with its regulation the fhkA promoter contains a putative E2F-type binding site (TTTGCGCCTTTT). Virtually all genes associated with replication fork progression are upregulated in the rblA disruptant these include cdc45 all mcm genes all gins genes all rfc genes four polA subunits three polD subunits two putatitive polE subunits PCNA the single-strand binding protein rfa1 the flap endonuclease repG as well as DNA ligase-1 and topoisomerase-2. All these genes show overexpression factors ranging from 4 to 15 DPPB0337b12.r1-5 CDS193587 1548 + 0.343669
g3285 PPL_03724 DPPB0337b12.r1-5 CDS196581 2538 + 0.36052
g3304 PPL_03740 DPPB0337b12.r1-5 CDS245492 3420 + 0.366374
g3310 PPL_03750 DPPB0337b12.r1-5 CDS264563 2262 - 0.369142
g3329 PPL_03770 similar to metazoan cyclin C predicted to interact with cyclin-dependent kinase DPPB0337b12.r1-5 CDS313270 438 + 0.360731
g3336 PPL_03778 DPPB0337b12.r1-5 CDS331939 2256 - 0.449468
g3351 PPL_03796 DPPB0337b12.r1-5 CDS377660 3288 + 0.328771
g3354 PPL_03798 DPPB0337b12.r1-5 CDS387208 1656 - 0.324879
g3376 PPL_03825 DPPB0337b12.r1-5 CDS453006 987 + 0.353597
g3382 PPL_03831 ortholog of Werner helicase-interacting protein 1 a modulator for initiation or reinitiation events during DNA polymerase delta-mediated DNA synthesis DPPB0337b12.r1-5 CDS465385 2277 + 0.333333
g340 PPL_00453 DPPA0004F08.r1-5_part2 CDS983217 1263 + 0.296912
g3472 PPL_13068 STE20PAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis contains PAK-boxP21-Rho-binding (CRIB) domain found in the WASP C-terminal DPPB0337b12.r1-5 CDS702838 2106 + 0.4283
g3482 PPL_03941 DPPB0337b12.r1-5 CDS728481 6978 + 0.36916
g3483 PPL_03943 DPPB0337b12.r1-5 CDS736078 1203 - 0.407315
g3505 PPL_03964 DPPB0337b12.r1-5 CDS787939 2094 - 0.391117
g3544 PPL_04008 DPPB0337b12.r1-5 CDS901449 2205 - 0.390476
g3559 PPL_04026 DPPB0337b12.r1-5 CDS943730 744 - 0.422043
g3567 PPL_04034 DPPB0337b12.r1-5 CDS965599 672 - 0.330357
g3591 PPL_04060 DPPB0337b12.r1-5 CDS1041218 3180 + 0.389937
g3676 PPL_04152 DPPB0337b12.r1-5 CDS1252659 1143 + 0.353456
g3685 PPL_04161 DPPB0337b12.r1-5 CDS1269979 2418 + 0.364764
g374 PPL_00487 DPPA0004F08.r1-5_part2 CDS1082196 2706 - 0.380636
g3741 PPL_13093 DPPB0360e11.f1-5 CDS119550 672 + 0.428571
g3762 PPL_04249 DPPB0360e11.f1-5 CDS171735 4806 - 0.354765
g3764 PPL_04254 DPPB0360e11.f1-5 CDS181632 336 - 0.419643
g3776 PPL_13101 DPPB0360e11.f1-5 CDS206478 2844 + 0.361111
g3803 PPL_04296 DPPB0360e11.f1-5 CDS317674 2934 - 0.403204
g3895 PPL_04401 DPPB0360e11.f1-5 CDS593813 1752 - 0.355594
g3926 PPL_04437 DPPB0360e11.f1-5 CDS692164 3075 - 0.358699
g3949 PPL_04460 DPPB0360e11.f1-5 CDS754155 3741 + 0.421812
g3976 PPL_04487 ortholog of S. cerevisiae TFB2 subunit of TFIIH and nucleotide excision repair factor 3 complexes involved in transcription initiation required for nucleotide excision repair DPPB0360e11.f1-5 CDS839751 1326 - 0.316742
g3995 PPL_04514 DPPB0360e11.f1-5 CDS912464 2025 + 0.361481
g4017 PPL_04535 controls the topological state of DNA by transient double-strand breakage and subsequent rejoining of DNA strands this is predicted to be a nuclear topoisomerase II DPPB0360e11.f1-5 CDS963730 4254 - 0.439586
g4060 PPL_13138 E0KFERV02EE9X2-3_part1 CDS50675 489 + 0.451943
g4061 PPL_04582 E0KFERV02EE9X2-3_part1 CDS51186 1647 + 0.414086
g4088 PPL_04612 E0KFERV02EE9X2-3_part1 CDS126560 2511 + 0.426523
g410 PPL_00527 DPPA0004F08.r1-5_part2 CDS1189816 4857 - 0.434836
g4105 PPL_04630 E0KFERV02EE9X2-3_part1 CDS178607 1197 + 0.385965
g4112 PPL_04637 similar to ATP-dependent RNA helicase M NAM7and to putative helicases involved in RNA maturation SEN1 human senataxin imlicated in ataxia-ocular apraxia 2 (AOA2) and amyotrophic lateral sclerosis 4 (ALS4) also belongs to this family E0KFERV02EE9X2-3_part1 CDS196633 2694 + 0.404232
g4125 PPL_04651 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene E0KFERV02EE9X2-3_part1 CDS236773 1950 + 0.417436
g4131 PPL_04658 E0KFERV02EE9X2-3_part1 CDS252988 1683 + 0.376708
g4140 PPL_04667 E0KFERV02EE9X2-3_part1 CDS274064 4098 + 0.425817
g4144 PPL_04673 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases E0KFERV02EE9X2-3_part1 CDS291180 951 + 0.37224
g4145 PPL_04674 E0KFERV02EE9X2-3_part1 CDS293141 6303 + 0.401396
g42 PPL_00124 DPPA0004F08.r1-5_part2 CDS114469 1170 + 0.300855
g4274 PPL_04830 E0KFERV02EE9X2-3_part1 CDS698387 2055 - 0.372749
g4281 PPL_04837 E0KFERV02EE9X2-3_part1 CDS715180 3810 - 0.427822
g4300 PPL_04853 E0KFERV02EE9X2-3_part1 CDS760265 10386 + 0.379838
g4302 PPL_04858 member of the TKL (tyrosine kinase-like) group of protein kinases contains filamin repeat similar to ABP120 E0KFERV02EE9X2-3_part1 CDS775755 4011 - 0.419097
g4341 PPL_04905 E0KFERV02EE9X2-3_part1 CDS881461 2238 - 0.395889
g4378 PPL_04956 E0KFERV02EE9X2-3_part2 CDS71022 1434 - 0.327755
g4390 PPL_04970 E0KFERV02EE9X2-3_part2 CDS97532 234 - 0.435897
g4420 PPL_05012 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases E0KFERV02EE9X2-3_part2 CDS200922 894 + 0.393736
g4423 PPL_05016 E0KFERV02EE9X2-3_part2 CDS207606 807 - 0.359356
g4427 PPL_05021 E0KFERV02EE9X2-3_part2 CDS216863 3555 - 0.37384
g444 PPL_00570 DPPA0004F08.r1-5_part2 CDS1291308 4569 + 0.408186
g4454 PPL_05049 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation E3JQK7F01CUWUC-3_part1 CDS5464 1680 + 0.370238
g4477 PPL_05074 ortholog of the DNA primase large subunit of the DNA polymerase alpha-primase complex required for the initiation of DNA replication E3JQK7F01CUWUC-3_part1 CDS60393 1455 + 0.408935
g4487 PPL_05084 E3JQK7F01CUWUC-3_part1 CDS85012 2190 - 0.356621
g4495 PPL_05094 E3JQK7F01CUWUC-3_part1 CDS101580 408 + 0.348039
g4511 PPL_05114 ATP-dependent DNA ligase contains the BRCT domain which is also found in BRCA1 forms a complex with XRCC4 E3JQK7F01CUWUC-3_part1 CDS143701 3195 - 0.369327
g4547 PPL_05151 E3JQK7F01CUWUC-3_part1 CDS257549 2799 - 0.410861
g4559 PPL_05164 E3JQK7F01CUWUC-3_part1 CDS282498 3201 + 0.403624
g4562 PPL_05166 E3JQK7F01CUWUC-3_part1 CDS291637 1887 + 0.396396
g4570 PPL_05177 putative protein serinethreonine kinase the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases stress-responsive kinase E3JQK7F01CUWUC-3_part1 CDS315075 3306 - 0.427707
g4593 PPL_05201 E3JQK7F01CUWUC-3_part1 CDS395361 1833 + 0.405892
g4594 PPL_05202 E3JQK7F01CUWUC-3_part1 CDS398970 1278 + 0.388106
g4616 PPL_05230 E3JQK7F01CUWUC-3_part1 CDS471714 723 - 0.290456
g462 PPL_00589 DPPA0004F08.r1-5_part2 CDS1349273 3159 + 0.405192
g4621 PPL_05234 E3JQK7F01CUWUC-3_part1 CDS488559 1209 + 0.362283
g4628 PPL_05241 E3JQK7F01CUWUC-3_part1 CDS511997 2172 + 0.383978
g4641 PPL_05256 E3JQK7F01DJJPS-5 CDS2088 3678 - 0.449973
g4650 PPL_05267 E3JQK7F01EFZL8-5 CDS26990 2160 + 0.409722
g4653 PPL_05270 E3JQK7F01EFZL8-5 CDS34250 7878 + 0.381696
g4655 PPL_05273 E3JQK7F01EFZL8-5 CDS47512 6747 - 0.431599
g4681 PPL_05303 E3JQK7F01EFZL8-5 CDS133514 3525 + 0.448511
g4696 PPL_05321 conserved RNA helicase S. cerevisiae ortholog PRP5 is necessary for pre-spliceosome formation E3JQK7F01EFZL8-5 CDS177338 3474 + 0.447323
g4737 PPL_05363 E3JQK7F01EFZL8-5 CDS298287 606 + 0.361386
g4752 PPL_05385 E3JQK7F01EFZL8-5 CDS339213 1836 - 0.36329
g4764 PPL_05397 E3JQK7F01EFZL8-5 CDS368499 2334 - 0.354327
g4815 PPL_05454 E3JQK7F01EFZL8-5 CDS531521 1005 + 0.460697
g4820 PPL_05458 E3JQK7F01EFZL8-5 CDS542170 1929 + 0.47071
g4828 PPL_05466 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation E3JQK7F01EFZL8-5 CDS573481 1677 - 0.431723
g4831 PPL_05469 ortholog of the yeast IRE1 serinethreonine kinaseendoribonuclease a transmembrane protein involved in the unfolded protein response contains a ribonuclease 2-5A domain and 3 pyrrolo-quinoline quinone (PQQ) domains E3JQK7F01EFZL8-5 CDS580253 2904 - 0.392562
g485 PPL_00618 similar to SRPKs (Serinearginine-Rich Protein specific Kinases) serinethreonine kinases that specifically phosphoryate arginine-serine rich domains found in the SR family of splicing factors DPPA0004F08.r1-5_part2 CDS1425003 1923 - 0.469579
g4863 PPL_05502 E3JQK7F01EFZL8-5 CDS666718 1425 - 0.382456
g4882 PPL_05525 E3JQK7F01EFZL8-5 CDS719763 3591 + 0.420496
g4913 PPL_05555 E3JQK7F01EFZL8-5 CDS797420 1521 - 0.324786
g4956 PPL_05599 putative protein serinethreonine kinase N-terminus similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase C-terminal half belongs to the peptidase C2 family contains 4 calpain III domains and has similarity to calpain-like cysteine protease E3JQK7F01EFZL8-5 CDS911672 1389 + 0.426926
g4959 PPL_05602 E3JQK7F01EFZL8-5 CDS916224 4557 - 0.426816
g4961 PPL_05605 similar to metazoan cyclin H predicted to interact with cyclin-dependent kinase E3JQK7F01EFZL8-5 CDS927818 1002 - 0.340319
g4978 PPL_05617 E3JQK7F01EFZL8-5 CDS968901 3579 - 0.347304
g5011 PPL_05653 E3JQK7F01EFZL8-5 CDS1062747 2676 - 0.408819
g5023 PPL_05664 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases E3JQK7F01EFZL8-5 CDS1084540 1029 - 0.409135
g5062 PPL_05710 E3JQK7F01EFZL8-5 CDS1183635 5982 + 0.367101
g5113 PPL_05761 E3JQK7F01EFZL8-5 CDS1334188 2145 - 0.440093
g5125 PPL_05771 similar to MCM5 a component of the Mcm2-7 hexameric complex that binds chromatin as a part of the pre-replicative complex E3JQK7F01EFZL8-5 CDS1371032 2178 + 0.339761
g5136 PPL_05783 DEADDEAH box helicases are involved in various aspects of RNA metabolism E3JQK7F01EFZL8-5 CDS1403435 3948 - 0.380952
g5141 PPL_05788 E3JQK7F01EFZL8-5 CDS1419509 2424 - 0.321782
g5173 PPL_05825 E3JQK7F02G10GF-5 CDS43000 3696 + 0.41342
g5182 PPL_05835 E3JQK7F02G10GF-5 CDS71368 2025 + 0.312593
g5184 PPL_05837 E3JQK7F02G10GF-5 CDS75635 2154 + 0.316156
g5211 PPL_05865 E3JQK7F02G10GF-5 CDS157349 2049 + 0.420205
g5247 PPL_05899 E3JQK7F02G10GF-5 CDS265927 1515 - 0.392079
g526 PPL_00660 DPPA0004F08.r1-5_part2 CDS1534288 2451 + 0.401469
g5280 PPL_05933 E3JQK7F02G10GF-5 CDS361424 915 - 0.360656
g5321 PPL_05970 putative protein serinethreonine kinase the kinase domain is similar to mitogen-activated protein kinases and other STE20-like kinases stress-responsive kinase E3JQK7F02G10GF-5 CDS462268 1443 - 0.462231
g5341 PPL_05994 E3JQK7F02G10GF-5 CDS530142 1416 + 0.418079
g5348 PPL_06000 hydrolyses alkylated adenine residues on DNA releasing 3-methyladenine E3JQK7F02G10GF-5 CDS550404 954 + 0.372117
g5349 PPL_06001 E3JQK7F02G10GF-5 CDS551728 558 + 0.369176
g5464 PPL_06131 E3JQK7F02GERJ7-5 CDS28443 2721 + 0.369717
g548 PPL_00681 DPPA0004F08.r1-5_part3 CDS45400 5994 + 0.385385
g5505 PPL_13248 E3JQK7F02GERJ7-5 CDS146205 540 - 0.403704
g5506 PPL_13249 E3JQK7F02GERJ7-5 CDS146937 546 - 0.413919
g5534 PPL_06199 serinethreonine protein kinase of the MAST (Microtubule Associated SerineThreonine kinase) family E3JQK7F02GERJ7-5 CDS236148 3480 + 0.347989
g5553 PPL_06218 E3JQK7F02HEVRT-5 CDS26718 4860 - 0.425103
g5564 PPL_06229 E3JQK7F02HEVRT-5 CDS51965 1587 - 0.376812
g5565 PPL_06230 E3JQK7F02HEVRT-5 CDS53921 1971 - 0.359716
g5598 PPL_06261 E3JQK7F02HEVRT-5 CDS147238 441 - 0.324263
g5600 PPL_06264 E3JQK7F02HEVRT-5 CDS152908 4779 + 0.3733
g5601 PPL_06265 E3JQK7F02HEVRT-5 CDS159924 3174 + 0.451166
g5602 PPL_06267 E3JQK7F02HEVRT-5 CDS164028 4494 + 0.373609
g5603 PPL_13259 E3JQK7F02HEVRT-5 CDS168820 1455 + 0.393814
g5608 PPL_06273 E3JQK7F02HEVRT-5 CDS188975 1410 + 0.357447
g5685 PPL_06365 E3JQK7F02HEVRT-5 CDS422165 3033 + 0.481372
g5690 PPL_06371 E3JQK7F02HEVRT-5 CDS443835 2187 - 0.382259
g5694 PPL_06375 E3JQK7F02HEVRT-5 CDS454750 4284 - 0.390289
g5791 PPL_06484 E3JQK7F02HP6OU-5 CDS20577 987 - 0.369808
g585 PPL_00718 DPPA0004F08.r1-5_part3 CDS137157 2052 + 0.30848
g5858 PPL_13285 E3JQK7F02HP6OU-5 CDS199442 1122 + 0.329768
g5861 PPL_06553 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases E3JQK7F02HP6OU-5 CDS210775 1545 + 0.37411
g5937 PPL_06640 E3JQK7F02HW0LE-5_part2 CDS146193 4167 + 0.397888
g5947 PPL_06657 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation E3JQK7F02HW0LE-5_part2 CDS182452 1938 + 0.398349
g5974 PPL_06692 E3JQK7F02HW0LE-5_part2 CDS254444 2715 - 0.414365
g5998 PPL_06719 E3JQK7F02HW0LE-5_part2 CDS317342 1554 + 0.337838
g600 PPL_00734 DPPA0004F08.r1-5_part3 CDS186398 1701 - 0.379189
g6007 PPL_06728 E3JQK7F02HW0LE-5_part2 CDS340837 1488 + 0.364919
g612 PPL_00744 DPPA0004F08.r1-5_part3 CDS217250 3255 + 0.399693
g615 PPL_12715 DPPA0004F08.r1-5_part3 CDS230338 3570 + 0.406162
g6182 PPL_06913 E3JQK7F02HW0LE-5_part2 CDS807155 1497 - 0.402138
g6244 PPL_06977 E3JQK7F02HW0LE-5_part2 CDS966281 2289 + 0.41765
g6251 PPL_06986 E3JQK7F02HW0LE-5_part2 CDS995117 2220 - 0.354054
g6315 PPL_07057 E3JQK7F02HW0LE-5_part2 CDS1202605 4974 - 0.368516
g6324 PPL_07066 E3JQK7F02HW0LE-5_part2 CDS1228456 690 + 0.375362
g6343 PPL_07087 member of the histone H2A-H2B sub-family related to the NF-YB subunit of the CCAAT-binding activator NF-Y E3JQK7F02HW0LE-5_part2 CDS1287578 444 - 0.317568
g6357 PPL_07101 DEADDEAH box helicases are involved in various aspects of RNA metabolism E3JQK7F02HW0LE-5_part2 CDS1333495 2202 - 0.435513
g6378 PPL_13331 E3JQK7F02HW0LE-5_part2 CDS1391535 1995 - 0.378446
g6384 PPL_07131 E3JQK7F02HW0LE-5_part2 CDS1408059 1533 + 0.439008
g6387 PPL_07135 E3JQK7F02HW0LE-5_part2 CDS1418892 2391 - 0.420744
g6404 PPL_07163 E3JQK7F02HW0LE-5_part2 CDS1463678 1431 - 0.346611
g6427 PPL_07188 E3JQK7F02HW0LE-5_part2 CDS1538082 1209 - 0.492969
g6428 PPL_07189 E3JQK7F02HW0LE-5_part2 CDS1541111 1518 + 0.40448
g6461 PPL_07224 E3JQK7F02HW0LE-5_part2 CDS1627614 2415 - 0.407867
g6463 PPL_07226 E3JQK7F02HW0LE-5_part2 CDS1631995 1053 + 0.37227
g6485 PPL_13336 E3JQK7F02HW0LE-5_part2 CDS1682441 687 + 0.465793
g6486 PPL_07251 ortholog of ATP-dependent RNA helicase DDX1 contains an SPRY domain which is of unknown function E3JQK7F02HW0LE-5_part2 CDS1683420 1467 + 0.39741
g651 PPL_00784 DPPA0004F08.r1-5_part3 CDS325152 1908 + 0.426625
g6514 PPL_07282 E3JQK7F02HW0LE-5_part2 CDS1758302 2397 - 0.459324
g6531 PPL_07301 E3JQK7F02HW0LE-5_part2 CDS1817724 2529 - 0.372875
g6541 PPL_07311 E3JQK7F02HW0LE-5_part2 CDS1844479 2016 + 0.397321
g6565 PPL_07339 E3JQK7F02HW0LE-5_part2 CDS1921436 1791 - 0.365159
g6578 PPL_07353 E3JQK7F02HW0LE-5_part2 CDS1959154 1893 + 0.416799
g6594 PPL_13341 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases EVG8W8Q01C9YYY-5_part1 CDS23439 996 + 0.364458
g6623 PPL_07407 EVG8W8Q01C9YYY-5_part1 CDS102877 8313 + 0.43041
g6670 PPL_07466 EVG8W8Q01C9YYY-5_part2 CDS43763 630 - 0.419048
g6695 PPL_07493 EVG8W8Q01C9YYY-5_part2 CDS110236 2418 - 0.35732
g670 PPL_00807 DPPA0004F08.r1-5_part3 CDS372642 1557 - 0.390495
g6714 PPL_07515 EVG8W8Q01C9YYY-5_part2 CDS168200 12471 + 0.402614
g6740 PPL_07543 EVG8W8Q01EEF2G-5 CDS40254 1836 - 0.39597
g6790 PPL_07600 EVG8W8Q01EEF2G-5 CDS184436 3471 - 0.428119
g68 PPL_12653 DPPA0004F08.r1-5_part2 CDS197752 2748 - 0.381732
g681 PPL_00820 DPPA0004F08.r1-5_part3 CDS403773 2061 + 0.33673
g6889 PPL_07710 EVG8W8Q02J3HU6-3_part1 CDS131536 2205 + 0.360998
g689 PPL_00831 DPPA0004F08.r1-5_part3 CDS421195 2298 + 0.397737
g6892 PPL_13357 EVG8W8Q02J3HU6-3_part1 CDS138495 1527 + 0.394237
g6902 PPL_07720 EVG8W8Q02J3HU6-3_part1 CDS161478 9174 + 0.405603
g6928 PPL_07746 contains one 5'-3' exonuclease domain and one 3'-5' exonuclease domain EVG8W8Q02J3HU6-3_part1 CDS228440 4236 - 0.396837
g695 PPL_00838 DPPA0004F08.r1-5_part3 CDS434153 1293 - 0.381284
g6955 PPL_07774 EVG8W8Q02J3HU6-3_part1 CDS315400 2382 - 0.319479
g6961 PPL_07785 EVG8W8Q02J3HU6-3_part1 CDS334841 4593 - 0.325713
g6973 PPL_07797 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases EVG8W8Q02J3HU6-3_part1 CDS373906 882 + 0.407029
g6987 PPL_07810 EVG8W8Q02J3HU6-3_part1 CDS410516 2319 - 0.310479
g7011 PPL_07834 EVG8W8Q02J3HU6-3_part1 CDS483527 2010 - 0.329851
g7023 PPL_07843 EVG8W8Q02J3HU6-3_part1 CDS516744 1998 - 0.412913
g7034 PPL_07852 EVG8W8Q02J3HU6-3_part1 CDS543792 2229 + 0.428892
g7088 PPL_07906 EVG8W8Q02J3HU6-3_part2 CDS32910 3204 - 0.401373
g7103 PPL_07920 EVG8W8Q02J3HU6-3_part2 CDS69310 2445 + 0.400818
g7120 PPL_07936 EVG8W8Q02J3HU6-3_part2 CDS105456 5748 + 0.385003
g7121 PPL_07937 EVG8W8Q02J3HU6-3_part2 CDS112026 1005 + 0.309453
g713 PPL_00861 DPPA0061d07.r1-5 CDS53398 1044 - 0.316092
g7131 PPL_07944 EVG8W8Q02J3HU6-3_part2 CDS135898 2196 - 0.387978
g7173 PPL_07991 EVG8W8Q02J3HU6-3_part2 CDS256346 3786 + 0.356049
g7179 PPL_08001 EVG8W8Q02J3HU6-3_part2 CDS279622 4344 - 0.369015
g7197 PPL_08023 EVG8W8Q02J3HU6-3_part2 CDS332463 2568 + 0.349688
g7242 PPL_08078 EVG8W8Q02J3HU6-3_part3 CDS87682 4071 + 0.362564
g7282 PPL_08128 EVG8W8Q02J3HU6-3_part3 CDS216592 1971 + 0.371892
g7301 PPL_08147 EVG8W8Q02J3HU6-3_part3 CDS262972 1473 - 0.424304
g7343 PPL_08192 EVG8W8Q02J3HU6-3_part3 CDS372962 4467 - 0.322364
g7375 PPL_08229 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation EVG8W8Q02J3HU6-3_part3 CDS459547 1317 - 0.422931
g7423 PPL_08290 EVG8W8Q02J3HU6-3_part3 CDS608978 3744 + 0.310897
g7507 PPL_08383 ortholog of Rad51 which is involved in activation of homologous recombination and double-strand break repair and interacts with XRCC3 there is a second copy of this gene EVG8W8Q02J3HU6-3_part3 CDS829797 1053 + 0.466287
g7524 PPL_08404 EVG8W8Q02J3HU6-3_part3 CDS876709 3396 - 0.352768
g759 PPL_00915 DPPA0061d07.r1-5 CDS166624 2751 + 0.430752
g7600 PPL_08495 EVG8W8Q02J3HU6-3_part3 CDS1111654 2529 - 0.40174
g7636 PPL_08532 EVG8W8Q02J3HU6-3_part3 CDS1200791 2343 + 0.331199
g7648 PPL_08548 highly similar to mammalian DNA-binding protein SMUBP-2 (IGHMBP2) involved in muscular atrophy and other diseases putative ortholog of S. cerevisiae HCS1 a DNA helicase associated with alpha DNA polymerase EVKQ3GG01CS5PZ-3_part1 CDS10796 2967 + 0.392315
g7717 PPL_08623 EVKQ3GG01CS5PZ-3_part1 CDS194383 5565 - 0.42911
g7722 PPL_08628 EVKQ3GG01CS5PZ-3_part1 CDS217392 990 + 0.406061
g7737 PPL_08643 EVKQ3GG01CS5PZ-3_part1 CDS254377 1971 + 0.381532
g7749 PPL_08655 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR WD40 and protein kinase domains EVKQ3GG01CS5PZ-3_part1 CDS298460 6687 + 0.425452
g7767 PPL_08681 EVKQ3GG01CS5PZ-3_part1 CDS352411 708 - 0.408192
g7792 PPL_08708 EVKQ3GG01CS5PZ-3_part1 CDS420647 1815 + 0.404408
g7802 PPL_08720 EVKQ3GG01CS5PZ-3_part1 CDS438959 2454 - 0.418093
g7815 PPL_08735 EVKQ3GG01CS5PZ-3_part1 CDS479597 597 + 0.371859
g7827 PPL_08748 EVKQ3GG01CS5PZ-3_part1 CDS509582 2790 - 0.383513
g786 PPL_00947 DPPA0061d07.r1-5 CDS275671 5256 + 0.451674
g7876 PPL_08801 member of the TKL (tyrosine kinase-like) group and the ARK (ankyrin repeat-containing kinase) family kinase activity stimulated by hyperosmolarity and heat shock there is a second copy of this gene EVKQ3GG01CS5PZ-3_part1 CDS661872 2262 + 0.433687
g7877 PPL_08802 EVKQ3GG01CS5PZ-3_part1 CDS665229 3105 + 0.393881
g7884 PPL_08811 EVKQ3GG01CS5PZ-3_part1 CDS690376 3126 - 0.410749
g7911 PPL_08841 EVKQ3GG01CS5PZ-3_part1 CDS765995 1761 + 0.362294
g7915 PPL_08847 EVKQ3GG01CS5PZ-3_part1 CDS783584 3285 + 0.402131
g7916 PPL_08848 EVKQ3GG01CS5PZ-3_part1 CDS787618 627 - 0.333333
g7983 PPL_08922 EVKQ3GG01CS5PZ-3_part1 CDS1009259 1530 - 0.443137
g7984 PPL_08925 ortholog of H. sapiens RFC3 (38 kDa subunit) and S. cerevisiae RFC5 EVKQ3GG01CS5PZ-3_part1 CDS1017048 1056 - 0.394886
g7993 PPL_08936 EVKQ3GG01CS5PZ-3_part1 CDS1053495 1287 + 0.363636
g7995 PPL_08938 EVKQ3GG01CS5PZ-3_part1 CDS1056769 2514 - 0.402148
g7996 PPL_08939 EVKQ3GG01CS5PZ-3_part1 CDS1059862 1326 + 0.456259
g8005 PPL_08948 atypical protein kinase belongs to the PIKK family of protein kinases similar to transformationtranscription domain-associated protein (TRRAP) EVKQ3GG01CS5PZ-3_part1 CDS1078944 12966 + 0.429585
g8020 PPL_08962 EVKQ3GG01CS5PZ-3_part1 CDS1124705 1803 + 0.476983
g8052 PPL_08992 EVKQ3GG01CS5PZ-3_part1 CDS1205775 486 + 0.41358
g8064 PPL_09006 EVKQ3GG01CS5PZ-3_part1 CDS1230451 855 + 0.45731
g8080 PPL_09023 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase ras EVKQ3GG01CS5PZ-3_part1 CDS1280112 5025 + 0.416119
g8093 PPL_09036 EVKQ3GG01CS5PZ-3_part1 CDS1312818 3021 - 0.37769
g8143 PPL_09090 EVKQ3GG01CS5PZ-3_part1 CDS1446158 2496 - 0.360577
g8144 PPL_09091 EVKQ3GG01CS5PZ-3_part1 CDS1451026 1263 - 0.353919
g8178 PPL_09122 EVKQ3GG01CS5PZ-3_part1 CDS1541850 3057 - 0.416421
g8197 PPL_09140 ortholog of H. sapiens xeroderma pigmentosum group D (XPD) M. musculus ERCC2 and S. cerevisiae RAD3 EVKQ3GG01CS5PZ-3_part1 CDS1590834 2346 - 0.410486
g8204 PPL_09147 similar to bacterial mismatch repair protein MutS putative mitochondrial mismatch repair protein EVKQ3GG01CS5PZ-3_part1 CDS1616424 2841 + 0.368532
g821 PPL_00989 DPPA0061d07.r1-5 CDS368949 2841 - 0.379444
g8219 PPL_09164 protein serinethreonine kinase CAMK group CAMK1 family similar to the Dictyostelium myosin light chain kinase (mlkA) and mammalian CAM kinases EVKQ3GG01CS5PZ-3_part1 CDS1659410 939 - 0.384452
g8243 PPL_09192 EVKQ3GG01CS5PZ-3_part1 CDS1726030 2805 - 0.325847
g8246 PPL_13460 AGC group AKT family protein serinethreonine kinase similar to other metazoan AktPKB including an N-terminal PH domain homologous kinase and C-terminal regulatory domains and phosphorylation sites required for AktPKB activation EVKQ3GG01CS5PZ-3_part1 CDS1740719 2499 + 0.42537
g8250 PPL_09199 EVKQ3GG01CS5PZ-3_part1 CDS1753790 3810 - 0.448819
g8264 PPL_09213 EVKQ3GG01CS5PZ-3_part1 CDS1789945 3642 - 0.377265
g8312 PPL_09273 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR and protein kinase domains there is a second copy of this gene EVKQ3GG01CS5PZ-3_part2 CDS56230 4878 + 0.46064
g8329 PPL_09289 EVKQ3GG01CS5PZ-3_part2 CDS113326 5130 - 0.366472
g8330 PPL_09290 EVKQ3GG01CS5PZ-3_part2 CDS119109 5556 - 0.382829
g8341 PPL_09301 member of the TKL (tyrosine kinase-like) group belongs to the ARK (ankyrin repeat-containing kinase) family although it does not contain ankyrin repeats contains two kinase domains one of which is predicted to be inactive EVKQ3GG01CS5PZ-3_part2 CDS150370 2640 - 0.325758
g8432 PPL_09407 EVKQ3GG01DB4K7-5 CDS397 7002 + 0.458012
g8448 PPL_12048 member of the TKL (tyrosine kinase-like) group and the ROCO family of protein kinases contains LRR Roc COR WD40 and protein kinase domains EVKQ3GG01DOIJB_part1 CDS37443 8415 - 0.442187
g8531 PPL_12150 EVKQ3GG01DOIJB_part1 CDS305147 1896 - 0.335443
g8541 PPL_12161 EVKQ3GG01DOIJB_part1 CDS333366 1542 - 0.398833
g8549 PPL_12173 EVKQ3GG01DOIJB_part1 CDS370306 7557 + 0.452825
g86 PPL_00178 DPPA0004F08.r1-5_part2 CDS253382 3288 - 0.395377
g8609 PPL_12238 EVKQ3GG01DOIJB_part1 CDS527136 4446 - 0.421502
g8614 PPL_12245 EVKQ3GG01DOIJB_part1 CDS541182 2361 - 0.379077
g8638 PPL_12271 EVKQ3GG01DOIJB_part1 CDS606317 1146 - 0.4363
g8657 PPL_12291 EVKQ3GG01DOIJB_part1 CDS673310 2571 + 0.423182
g8659 PPL_12293 putative protein serinethreonine kinase similar to yeast CDC5 Drosophila polo and mammalian PLK which play a role in mitosis and localize to the centrosomes EVKQ3GG01DOIJB_part1 CDS678121 2337 - 0.353872
g8667 PPL_12302 putative protein serinethreonine kinase similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase EVKQ3GG01DOIJB_part1 CDS697799 2229 - 0.374159
g8688 PPL_12323 similar to eukaryotic translation initiation factor 4A isoform 2 EVKQ3GG01DOIJB_part1 CDS756580 1161 - 0.458226
g87 PPL_00179 DPPA0004F08.r1-5_part2 CDS257178 1950 - 0.423077
g8735 PPL_12376 EVKQ3GG01DOIJB_part2 CDS60686 1446 - 0.397649
g874 PPL_01041 similar to eukaryotic translation initiation factor 4A isoform 2 DPPA0061d07.r1-5 CDS493267 1251 + 0.423661
g8765 PPL_12404 EVKQ3GG01DOIJB_part2 CDS135535 1425 - 0.374035
g8773 PPL_12413 belongs to a superfamily of metalloenzymes induced by Legionella pneumophila infection EVKQ3GG01DOIJB_part2 CDS149994 1050 - 0.42381
g8785 PPL_12427 STE20PAKA protein kinase involved in the regulation of the cytoskeleton during chemotaxis and required for cytokinesis contains PAK-boxP21-Rho-binding (CRIB) domain found in the WASP C-terminal EVKQ3GG01DOIJB_part2 CDS174884 2844 - 0.460267
g8792 PPL_12433 EVKQ3GG01DOIJB_part2 CDS202928 3798 - 0.398631
g8798 PPL_12439 EVKQ3GG01DOIJB_part2 CDS218508 3066 - 0.390737
g8826 PPL_12469 EVKQ3GG01DOIJB_part2 CDS290449 1785 - 0.371989
g8829 PPL_12472 EVKQ3GG01DOIJB_part2 CDS299039 4557 + 0.412552
g8839 PPL_13498 similar to eukaryotic initiation factor 4A isoform 3 EVKQ3GG01DOIJB_part2 CDS329013 1269 - 0.41056
g8846 PPL_12492 EVKQ3GG01DOIJB_part2 CDS363537 2835 + 0.402822
g8854 PPL_12502 EVKQ3GG01DOIJB_part2 CDS383818 2379 - 0.374527
g8855 PPL_12503 EVKQ3GG01DOIJB_part2 CDS386636 6582 - 0.393649
g8874 PPL_12520 putative cell division cycle 2 (CDC2)-like protein kinase has similarity to PITSLRE proteins and other cyclin-dependent kinase 2 kinases EVKQ3GG01DOIJB_part2 CDS441093 888 - 0.399775
g8885 PPL_12530 EVKQ3GG01DOIJB_part2 CDS478319 6942 - 0.438346
g891 PPL_01057 DPPA0061d07.r1-5 CDS560534 1674 + 0.339307
g8916 PPL_12566 EVKQ3GG01DOIJB_part2 CDS575383 5529 - 0.421776
g8933 PPL_12592 putative protein serinethreonine kinase N-terminus similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase C-terminal half belongs to the peptidase C2 family contains 4 calpain III domains and has similarity to calpain-like cysteine protease EVKQ3GG01DOIJB_part2 CDS634721 3390 + 0.439823
g8946 PPL_12605 EVKQ3GG01DOIJB_part2 CDS673815 1257 - 0.38027
g8967 PPL_12628 EVKQ3GG01DOIJB_part2 CDS756017 1233 - 0.430657
g8974 PPL_12634 EVKQ3GG01DOIJB_part2 CDS772883 1167 - 0.396744
g898 PPL_01064 DPPA0061d07.r1-5 CDS578661 504 - 0.434524
g9009 PPL_09432 EVKQ3GG02I325Y-5_part1 CDS66777 1890 + 0.416402
g9033 PPL_13511 EVKQ3GG02I325Y-5_part1 CDS133136 1638 - 0.383394
g9043 PPL_09468 EVKQ3GG02I325Y-5_part1 CDS162709 1563 - 0.350608
g9098 PPL_09530 conserved splice factor that is required for the first ATP-dependent step in spliceosome assembly and for the interaction of U2 snRNP with the branchpoint the human ortholog (BAT1) forms a homodimer and interacts directly with EVKQ3GG02I325Y-5_part1 CDS336425 1158 + 0.462867
g9138 PPL_09567 EVKQ3GG02I325Y-5_part1 CDS449520 2055 + 0.445255
g914 PPL_01082 putative protein serinethreonine kinase belongs to the protein kinase PAKL subfamily the kinase domain is similar to mammalian STK3 and STK4 (MST) kinases and other STE20-like kinases stress-responsive kinase DPPA0061d07.r1-5 CDS633177 3357 + 0.408102
g9179 PPL_09609 EVKQ3GG02I325Y-5_part1 CDS558229 4470 + 0.414989
g9184 PPL_09614 EVKQ3GG02I325Y-5_part1 CDS579156 1734 + 0.317762
g9191 PPL_09621 EVKQ3GG02I325Y-5_part1 CDS597260 1677 - 0.371497
g9216 PPL_09645 EVKQ3GG02I325Y-5_part1 CDS667122 888 - 0.406532
g9246 PPL_09681 EVKQ3GG02I325Y-5_part1 CDS750668 3201 + 0.40706
g9275 PPL_09714 EVKQ3GG02I325Y-5_part1 CDS820568 1887 - 0.401166
g9296 PPL_09737 EVKQ3GG02I325Y-5_part1 CDS861062 4539 - 0.388632
g932 PPL_01097 DPPA0061d07.r1-5 CDS675748 4065 - 0.428044
g9340 PPL_09788 EVKQ3GG02I325Y-5_part1 CDS992854 720 + 0.326389
g936 PPL_01102 DPPA0061d07.r1-5 CDS692229 4233 - 0.419561
g9376 PPL_09824 EVKQ3GG02I325Y-5_part1 CDS1145981 3276 - 0.392552
g9395 PPL_09848 EVKQ3GG02I325Y-5_part1 CDS1189329 3576 + 0.376958
g9436 PPL_09893 EVKQ3GG02I325Y-5_part1 CDS1323159 2460 - 0.408943
g9453 PPL_09912 EVKQ3GG02I325Y-5_part2_part2 CDS14886 942 + 0.339703
g9468 PPL_09926 EVKQ3GG02I325Y-5_part2_part2 CDS58147 1914 + 0.361024
g9513 PPL_09984 EWNM59D01C4IL7-5_part1 CDS48487 2823 + 0.332625
g9518 PPL_09991 EWNM59D01C4IL7-5_part1 CDS62276 1884 + 0.402866
g9567 PPL_10045 EWNM59D01C4IL7-5_part1 CDS186009 4404 - 0.359446
g9584 PPL_10060 EWNM59D01C4IL7-5_part1 CDS233173 2532 + 0.411137
g9614 PPL_10095 EWNM59D01C4IL7-5_part1 CDS322394 1836 - 0.336601
g9625 PPL_10106 EWNM59D01C4IL7-5_part1 CDS348175 2397 - 0.373801
g9636 PPL_10118 EWNM59D01C4IL7-5_part1 CDS372553 2868 - 0.416318
g9647 PPL_10132 EWNM59D01C4IL7-5_part1 CDS410091 4326 - 0.36662
g9700 PPL_10184 EWNM59D01C4IL7-5_part1 CDS575239 3672 + 0.430828
g971 PPL_01137 DPPA0061d07.r1-5 CDS782243 5799 + 0.416106
g9718 PPL_10212 EWNM59D01C4IL7-5_part1 CDS642374 2625 - 0.470857
g9745 PPL_10241 EWNM59D01C4IL7-5_part1 CDS720108 2595 + 0.35183
g9750 PPL_10247 EWNM59D01C4IL7-5_part1 CDS733244 1560 + 0.444872
g9806 PPL_10322 EWNM59D01C4IL7-5_part1 CDS920082 2178 + 0.341598
g9824 PPL_10340 EWNM59D01C4IL7-5_part1 CDS959812 3849 + 0.376202
g9826 PPL_10342 EWNM59D01C4IL7-5_part1 CDS964362 3678 + 0.383904
g9836 PPL_10353 EWNM59D01C4IL7-5_part1 CDS990870 1440 - 0.355556
g9848 PPL_10365 EWNM59D01C4IL7-5_part1 CDS1019195 2634 - 0.393318
g9904 PPL_10427 EXOLTKG01B86TH-3_part2 CDS21939 3177 - 0.400692
g9908 PPL_10432 EXOLTKG01B86TH-3_part2 CDS38487 1311 - 0.278413
g991 PPL_01155 DPPA0061d07.r1-5 CDS839396 2166 + 0.354109
g9952 PPL_10482 EXOLTKG01B86TH-3_part2 CDS161742 4467 + 0.412581
g9992 PPL_10521 EXOLTKG01B86TH-3_part2 CDS267254 7857 + 0.432226
sepA PPL_00495 plays a role in the regulation of cleavage furrow formation similar to S. pombe cdc7 DPPA0004F08.r1-5_part2 CDS1109631 3249 - 0.426901