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2024-05-19 15:00:30

Gene list

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COG category: Nucleotide transport and metabolism
Organism: Dictyostelium discoideum AX4, AX4

Number of genes found: 102

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Show UniProt / TrEMBL protein name View in Fasta format (DNA) View in Fasta format (Protein)  

 
Dictyostelium discoideum AX4, AX4
NameLocus tagProduct / DescriptionGenomic elementTypeBeginLengthStrandGC-content
DDB_G0268194 DDB_G0268194 catalyzes the reaction Hsub2subO dCTP - NH3 dUTP in de novo biosynthesis of pyrimidine deoxyribonucleotidesDDB0232428 CDS1641107 768 - 0.311198
DDB_G0271914 DDB_G0271914 DDB0232429 CDS1000440 675 - 0.358519
DDB_G0272030 DDB_G0272030 DDB0232429 CDS1189650 678 - 0.361357
DDB_G0272048 DDB_G0272048 DDB0232429 CDS1193466 1176 - 0.271259
DDB_G0272442 DDB_G0272442 DDB0232429 CDS1598330 705 - 0.307801
DDB_G0272839 DDB_G0272839 has a short region of similarity to aprataxin a Hint related protein that is mutated in individuals with ataxia with oculomotor apraxiaDDB0232429 CDS2148504 1173 + 0.224211
DDB_G0273137 DDB_G0273137 there is a second copy of this gene DDB0232429 CDS2854787 1818 + 0.262376
DDB_G0273617 DDB_G0273617 there is a second copy of this gene DDB0232429 CDS3174939 1818 - 0.262376
DDB_G0275179 DDB_G0275179 similar to H. sapiens CECR1 protein (Swiss Prot Q9NZK5)DDB0232429 CDS5345936 1632 + 0.273284
DDB_G0275307 DDB_G0275307 DDB0232429 CDS5319128 810 - 0.22716
DDB_G0275667 DDB_G0275667 homolog of human and S. cerevisiae KTI12 (killer toxin insensitivity protein 12) S. cerevisiae KTI12 interacts with the Elongator complex a component of the elongating form of RNA polymerase II DDB0232429 CDS5787522 822 - 0.283455
DDB_G0276407 DDB_G0276407 DDB0232429 CDS6832640 1236 + 0.279935
DDB_G0277355 DDB_G0277355 DDB0232429 CDS7838828 969 - 0.415893
DDB_G0277515 DDB_G0277515 DDB0232429 CDS8077667 1542 - 0.323606
DDB_G0277559 DDB_G0277559 contains a predicted signal peptide and a putative C-terminal transmembrane domain similar to D. purpureum proteinDDB0232429 CDS8125465 1938 - 0.209494
DDB_G0278493 DDB_G0278493 DDB0232430 CDS967226 528 + 0.263258
DDB_G0278573 DDB_G0278573 DDB0232430 CDS1094317 810 + 0.245679
DDB_G0278841 DDB_G0278841 DDB0232430 CDS1265394 1560 - 0.253846
DDB_G0281219 DDB_G0281219 DDB0232430 CDS4234799 1131 - 0.290893
DDB_G0282171 DDB_G0282171 DDB0232430 CDS5485189 684 - 0.387427
DDB_G0282255 DDB_G0282255 DDB0232430 CDS5579876 1152 - 0.366319
DDB_G0285299 DDB_G0285299 DDB0232431 CDS3070354 1635 - 0.310092
DDB_G0285467 DDB_G0285467 DDB0232431 CDS3266519 1398 + 0.326896
DDB_G0285539 DDB_G0285539 DDB0232431 CDS3354945 1575 + 0.233016
DDB_G0286085 DDB_G0286085 DDB0232431 CDS4039412 1188 - 0.222222
DDB_G0286161 DDB_G0286161 DDB0232431 CDS4152139 1269 + 0.291568
DDB_G0287551 DDB_G0287551 DDB0232432 CDS406658 1368 + 0.284357
DDB_G0287753 DDB_G0287753 DDB0232432 CDS656012 891 + 0.251403
DDB_G0287839 DDB_G0287839 DDB0232432 CDS789237 1452 + 0.309917
DDB_G0287985 DDB_G0287985 DDB0232432 CDS933669 912 + 0.3125
DDB_G0288019 DDB_G0288019 DDB0232432 CDS981451 720 - 0.306944
DDB_G0288099 DDB_G0288099 DDB0232432 CDS1100340 765 - 0.256209
DDB_G0289439 DDB_G0289439 DDB0232432 CDS2778983 405 + 0.367901
DDB_G0291478 DDB_G0291478 DDB0232433 CDS405733 1263 - 0.257324
DDB_G0291764 DDB_G0291764 related to ribonucleotide reductase small subunit missing about 25DDB0232433 CDS704842 774 + 0.239018
DDB_G0292080 DDB_G0292080 DDB0232433 CDS1159633 972 + 0.359053
DDB_G0292096 DDB_G0292096 contains a cytidine and deoxycytidylate deaminase zinc-binding region contains a carbohydrate-binding domain contains a predicted signal peptideDDB0232433 CDS1176701 966 - 0.421325
DDB_G0292246 DDB_G0292246 DDB0232433 CDS1370987 891 + 0.274972
DDB_G0292298 DDB_G0292298 DDB0232433 CDS1424473 501 - 0.307385
DDB_G0292928 DDB_G0292928 DDB0232433 CDS2282811 483 - 0.233954
DDB_G0293580 DDB_G0293580 catalyzes the reaction Hsub2subO dCTP NH3 dUTP in de novo biosynthesis of pyrimidine deoxyribonucleotidesDDB0232433 CDS3073231 525 - 0.289524
ada DDB_G0287371 catalyzes the reaction Hsub2subO adenosine NHsub3sub inosine in salvage pathways of nucleosides contains two tandem repeats of the adenosine deaminase domainDDB0232432 CDS206705 2319 + 0.287193
adkA DDB_G0283805 catalyzes the reaction AMP ATP ADP ADP in de novo DNA synthesisDDB0232431 CDS1124176 831 - 0.32491
adkB DDB_G0292730 catalyzes the reaction AMP ATP ADP ADP in de novo DNA synthesis predicted to be nuclearDDB0232433 CDS2003598 699 - 0.291846
allB1 DDB_G0282199 catalyzes the reaction Hsub2subO allantoin allantoateDDB0232430 CDS5513834 1950 + 0.318462
allB2 DDB_G0270162 catalyzes the reaction Hsub2subO allantoin allantoate expressed in upper cup cells during culminationDDB0232428 CDS4345093 1533 + 0.262231
allC DDB_G0280267 catalyzes the reaction allantoate Hsub2subO (S)-ureidoglycolate urea in allantoin degradationDDB0232430 CDS3183979 1110 + 0.336036
amdA DDB_G0292266 required for spore formation inhibits the formation of aspidocytes catalyzes the reaction AMP Hsub2subO IMP NHsub3subbr bNomenclature conflict: b Do not confuse this gene with amd1 encoding S-adenosylmethionine decarboxylaseDDB0232433 CDS1491265 2373 - 0.313527
aprt DDB_G0270174 catalyzes the reaction AMP pyrophosphate PRPP adenine in nucleoside salvage pathwaysDDB0232428 CDS4368158 600 + 0.29
cda DDB_G0288933 catalyzes the reactions cytidine Hsub2subO uridine NHsub3sub and Hsub2subO deoxycytidine NHsub3sub deoxyuridineDDB0232432 CDS2144804 444 - 0.351351
ctps DDB_G0280567 catalyzes the reaction L-glutamine Hsub2subO UTP ATP - CTP phosphate ADP L-glutamate in de novo biosynthesis of pyrimidine ribonucleotidesDDB0232430 CDS3510967 1710 - 0.350292
dak DDB_G0278191 catalyzes the reaction ATP deoxyadenosine ADP dAMPDDB0232430 CDS426271 738 + 0.285908
dgk DDB_G0280843 catalyzes the reaction ATP deoxyguanosine ADP dGMPDDB0232430 CDS1424429 858 - 0.226107
dtymk DDB_G0290033 catalyzes the reaction dTMP ATP dTDP ADP in de novo biosynthesis of pyrimidine deoxyribonucleotidesDDB0232432 CDS3573621 669 - 0.258595
dut DDB_G0293374 catalyses the reaction Hsub2subO dUTP pyrophosphate dUMP in de novo biosynthesis of pyrimidine deoxyribonucleotidesDDB0232433 CDS2804871 540 - 0.327778
fhit DDB_G0274257 ortholog of human FHIT which is a possible tumor suppressor for specific tissues numerous tumor types are associated with aberrant forms of human FHIT proteinDDB0232429 CDS4124527 450 - 0.311111
fthS DDB_G0290397 catalyzes the reaction ATP formate tetrahydrofolate ADP phosphate N10-formyl-Hsub4subF in various biosynthetic pathways in plants and in Dictyostelium this is a monofunctional enzyme while in yeast and in metazoan the same enzyme has two additional activities encoded by DDB0232432 CDS4031914 1917 + 0.383933
gghA DDB_G0286535 DDB0232431 CDS4609676 954 - 0.328092
gghB DDB_G0289365 DDB0232432 CDS2708637 1044 - 0.229885
gmkA DDB_G0279001 catalyzes the reaction GMP ATP GDP ADP in the de novo and salvage pathways of purine and pyrimidine nucleotidesDDB0232430 CDS1502267 609 + 0.279146
guaA DDB_G0281551 catalyzes the reaction xanthosine-5-phosphate Hsub2subO L-glutamine ATP L-glutamate GMP pyrophosphate AMP in GMP biosynthesisDDB0232430 CDS4709076 2157 + 0.304126
guaB DDB_G0283701 catalyzes the reaction Hsub2subO NAD IMP xanthosine-5-phosphate NADH the first step of GMP biosynthesisDDB0232431 CDS1000722 1548 - 0.386305
guaD DDB_G0277743 catalyzes the reaction guanine Hsub2subO xanthine NHsub3subDDB0232429 CDS8417392 1353 + 0.311899
hprT DDB_G0285193 catalyzes the reaction PRPP hypoxanthine pyrophosphate IMP in the salvage pathways of purine nucleosides br overexpressed in dstB (STATb) null mutantsDDB0232431 CDS2972049 543 + 0.281768
itpa DDB_G0286495 ortholog of human ITPA and S. cerevisiae HAM1 hydrolyzes ITP and dITP to their respective monophosphate derivatives defects in human ITPA cause inosine triphosphate pyrophosphohydrolase deficiency characterized by an abnormal accumulation of inosine triphosphate in erythrocytes however pathological symptoms are not knownDDB0232431 CDS4555858 585 - 0.309402
iunH DDB_G0272738 catalyzes the reaction N-D-ribosylpurine Hsub2subO purine D-riboseDDB0232429 CDS2227186 1023 + 0.311828
mcfZ DDB_G0293874 belongs to the substrate carrier protein family involved in transport of molecules across the mitochondrial membrane expressed in pstAO cells and in upper and lower cups during culminationbrbr bCommunity annotation:b Overview of the DDB0232433 CDS3410167 906 + 0.36755
mth DDB_G0293766 DDB0232433 CDS3300203 486 + 0.238683
ndkC-1 DDB_G0273069 catalyzes the phosphorylation of nucleoside or deoxynucleoside diphosphates into the corresponding triphosphates there is a second copy of this gene DDB0232429 CDS2603092 468 - 0.397436
ndkC-2 DDB_G0273805 catalyzes the phosphorylation of nucleoside or deoxynucleoside diphosphates into the corresponding triphosphates there is a second copy of this gene DDB0232429 CDS3427961 468 + 0.397436
ndkM DDB_G0279911 DDB0232430 CDS2740248 663 + 0.380091
ndrJ DDB_G0292654 similar to class II ribonucleotide reductase a monomeric form of ribonucleotide reductase that uses ribonucletide triphosphates rather than diphosphates as substrates the only other eukaryote in which this enzyme is present is Euglena gracilisDDB0232433 CDS1906693 2277 + 0.312692
pkiA DDB_G0289391 DDB0232432 CDS2783089 384 + 0.351562
prsA DDB_G0284669 ortholog of PRS involved in nucleotide histidine and tryptophan biosynthesisDDB0232431 CDS2322296 954 + 0.318658
prsB DDB_G0272246 highly similar to PRS involved in nucleotide histidine and tryptophan biosynthesisDDB0232429 CDS1758981 990 - 0.29596
prsC DDB_G0283627 highly similar to PRS involved in nucleotide histidine and tryptophan biosynthesisDDB0232431 CDS883884 966 - 0.284679
purA DDB_G0285429 catalyzes the reaction L-aspartate IMP GTP adenylo-succinate phosphate GDP in de novo DNA synthesisDDB0232431 CDS3358729 1284 + 0.348131
purB DDB_G0288333 catalyzes two reactions in de novo DNA synthesis: 5'-phosphoribosyl-4-(N-succinocarboxamide)-5-aminoimidazole fumarate AICAR and adenylo-succinate fumarate AMPDDB0232432 CDS1402047 1401 + 0.33262
purC%2FE DDB_G0283987 bifunctional enzyme composed of SAICAR synthase and AIR carboxylase that catalyze steps in de novo DNA synthesisDDB0232431 CDS1280148 2994 + 0.325985
purD DDB_G0290121 bifunctional enzyme of the de novo DNA synthesis pathway contains aminoimidazole ribotide synthetase and glycinamide ribotide synthetase activitiesDDB0232432 CDS3683216 2448 + 0.318219
purF DDB_G0274321 catalyzes the reaction L-glutamine PRPP Hsub2subO 5-phospho-beta-D-ribosyl-amine pyrophosphate L-glutamate the first step in de novo DNA synthesisDDB0232429 CDS3954678 1566 + 0.393997
purH DDB_G0277087 bifunctional enzyme that catalyzes the reactions Nsup10sup-formyl-Hsub4subF AICAR tetrahydrofolate phosphoribosyl-formamido-carboxamide and phosphoribosyl-formamido-carboxamide IMP Hsub2subO expressed in prespore cellsDDB0232429 CDS7485197 1629 - 0.349908
purL DDB_G0288145 catayzes the reaction ATP 5'-phosphoribosyl-N-formylglycineamide L-glutamine Hsub2subO ADP phosphate 5-phosphoribosyl-n-formylglycineamidine L-glutamate in de novo DNA synthesisDDB0232432 CDS1141268 4068 + 0.342429
purN DDB_G0288985 catalyzes the reaction N10-formyl-Hsub4subF 5-phospho-ribosyl-glycineamide tetrahydrofolate 5'-phosphoribosyl-N-formylglycineamide in de novo DNA synthesisDDB0232432 CDS2206145 621 + 0.275362
pyd2 DDB_G0269246 ortholog of the human DPYS defects in DPYS cause cause of DHP (dihydropyrimidinase) deficiency second enzyme in the reductive pyrimidine degradation pathway (EC 3.5.2.2) catalyzes the reaction: 56-dihydrouracil Hsub2subO 3-ureidopropanoateDDB0232428 CDS3157203 1512 - 0.355159
pyr1-3 DDB_G0276335 multifunctional enzyme that carries out the three first enzymatic activities of the de novo pyrimidine biosynthetic pathway very similar to the tri-functional human CAD enzymeDDB0232429 CDS6728694 6678 + 0.351003
pyr4 DDB_G0276331 catalyzes the reaction Osub2sub dihydroorotate Hsub2subOsub2sub orotate in de novo biosynthesis of pyrimidine ribonucleotidesDDB0232429 CDS6726246 1113 - 0.34142
pyr56 DDB_G0280041 bifunctional enzyme that catalyzes the reactions PRPP orotate orotidine-5'-phosphate pyrophosphate and orotidine-5'-phosphate COsub2sub UMP in de novo biosynthesis of pyrimidine ribonucleotidesDDB0232430 CDS3010631 1437 + 0.338205
pyrK DDB_G0287495 phosphorylates dCMP and dUMP to dCDP and dUDP respectivelyDDB0232432 CDS334067 588 + 0.289116
rnrA DDB_G0284071 catalyzes the reaction 2'-deoxyribonucleoside diphosphate thioredoxin disulfide Hsub2subO ribonucleoside diphosphate reduced thioredoxinDDB0232431 CDS1503516 2613 + 0.381554
rnrB-1 DDB_G0272616 catalyzes the reaction 2'-deoxyribonucleoside diphosphate thioredoxin disulfide Hsub2subO ribonucleoside diphosphate reduced thioredoxin there is a second copy of this gene DDB0232429 CDS2355911 1017 + 0.301868
rnrB-2 DDB_G0274021 catalyzes the reaction 2'-deoxyribonucleoside diphosphate thioredoxin disulfide Hsub2subO ribonucleoside diphosphate reduced thioredoxin there is a second copy of this gene DDB0232429 CDS3674573 1017 - 0.301868
thyA DDB_G0280045 catalyzes the reaction 510-methylenetetrahydrofolate dUMP FADHsub2sub dTMP tetrahydrofolate FAD in de novo biosynthesis of pyrimidine deoxyribonucleotidesDDB0232430 CDS3175236 912 + 0.337719
thyB DDB_G0289179 calmodulin-binding thymidine kinase 1 that is very similar to human TK1 catalyzes the reaction ATP thymidine ADP thymidine 5'-phosphateDDB0232432 CDS2508266 684 - 0.330409
udkA DDB_G0269034 catalyzes the reaction ATP uridine ADP UMPDDB0232428 CDS2213969 1500 - 0.292
udkB DDB_G0274559 catalyzes the reaction ATP uridine ADP UMPDDB0232429 CDS4144032 732 - 0.325137
udkC DDB_G0283371 contains a N-terminal uridine kinase domaine domain and a C-terminal adenylate cyclase domain like the UdkD protein and other plant proteinsDDB0232431 CDS600577 1350 - 0.297778
udkD DDB_G0271146 contains a N-terminal uridine kinase domaine domain and a C-terminal adenylate cyclase domain like the UdkC protein and other plant proteinsDDB0232429 CDS69676 1479 - 0.294118
udpA DDB_G0284431 catalyzes the reaction phosphate uridine ribose-1-phosphate uracil in salvage pathways of pyrimidine ribonucleotides and deoxyribose phosphate degradationDDB0232431 CDS1983105 750 - 0.4
udpB DDB_G0280985 catalyzes the reaction phosphate uridine ribose-1-phosphate uracil in salvage pathways of pyrimidine ribonucleotides and deoxyribose phosphate degradationDDB0232430 CDS3914149 870 - 0.310345
uprt DDB_G0267560 catalyzes the reaction UMP diphosphate uracil 5-phospho-alpha-D-ribose 1-diphosphateDDB0232428 CDS336383 651 + 0.294931
xdh DDB_G0291047 catalyzes the reactions xanthine NAD Hsub2subO urate NADH H and xanthine Hsub2subO Osub2sub urate Hsub2subOsub2subDDB0232432 CDS4822800 4077 + 0.347559