Gene list
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COG category: Cytoskeleton
Organism: Dictyostelium discoideum AX4, AX4
Number of genes found: 134
Show UniProt / TrEMBL protein name | View in Fasta format (DNA) | View in Fasta format (Protein) | ||||
Dictyostelium discoideum AX4, AX4 | ||||||||
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Name | Locus tag | Product / Description | Genomic element | Type | Begin | Length | Strand | GC-content |
ChLim | DDB_G0267490 | contains a N-terminal Calponin Homology (CH) domain 3 LIM domains and 4 LIM-related domains (LRDs) | DDB0232428 | CDS | 212712 | 2061 | - | 0.311499 |
DDB_G0267586 | DDB_G0267586 | DDB0232428 | CDS | 375348 | 1389 | + | 0.267099 | |
DDB_G0267974 | DDB_G0267974 | DDB0232428 | CDS | 1214003 | 2865 | - | 0.264223 | |
DDB_G0269700 | DDB_G0269700 | DDB0232428 | CDS | 3352107 | 2622 | + | 0.249809 | |
DDB_G0269934 | DDB_G0269934 | DDB0232428 | CDS | 3897216 | 6135 | + | 0.351263 | |
DDB_G0270246 | DDB_G0270246 | DDB0232428 | CDS | 4514326 | 1725 | - | 0.225507 | |
DDB_G0274781 | DDB_G0274781 | contains three EF hands similar to mammalian neuron specific calcium-binding protein hippocalcin belongs to the frequenins a family of myristoyl-switch calcium-binding proteins | DDB0232429 | CDS | 3825256 | 678 | + | 0.29646 |
DDB_G0276695 | DDB_G0276695 | DDB0232429 | CDS | 7141543 | 1941 | + | 0.301391 | |
DDB_G0277429 | DDB_G0277429 | DDB0232429 | CDS | 8039644 | 2550 | - | 0.296863 | |
DDB_G0278125 | DDB_G0278125 | DDB0232430 | CDS | 327348 | 2496 | - | 0.333333 | |
DDB_G0278255 | DDB_G0278255 | DDB0232430 | CDS | 568794 | 1545 | - | 0.260841 | |
DDB_G0279253 | DDB_G0279253 | DDB0232430 | CDS | 1838283 | 1539 | - | 0.238467 | |
DDB_G0279435 | DDB_G0279435 | DDB0232430 | CDS | 2045716 | 1461 | - | 0.299795 | |
DDB_G0281767 | DDB_G0281767 | DDB0232430 | CDS | 4930354 | 2652 | + | 0.255656 | |
DDB_G0282633 | DDB_G0282633 | DDB0232430 | CDS | 6031309 | 2760 | + | 0.285507 | |
DDB_G0282859 | DDB_G0282859 | DDB0232430 | CDS | 6316518 | 1890 | + | 0.232804 | |
DDB_G0283369 | DDB_G0283369 | DDB0232431 | CDS | 587429 | 6252 | - | 0.274152 | |
DDB_G0284145 | DDB_G0284145 | DDB0232431 | CDS | 1523365 | 1317 | - | 0.2612 | |
DDB_G0285261 | DDB_G0285261 | DDB0232431 | CDS | 3027528 | 1266 | + | 0.239336 | |
DDB_G0285265 | DDB_G0285265 | contains one EF hand similar to calmodulin | DDB0232431 | CDS | 3032493 | 420 | - | 0.292857 |
DDB_G0292586 | DDB_G0292586 | DDB0232433 | CDS | 1803595 | 1368 | + | 0.29386 | |
DDB_G0292664 | DDB_G0292664 | DDB0232433 | CDS | 1919877 | 531 | + | 0.354049 | |
DDB_G0293756 | DDB_G0293756 | DDB0232433 | CDS | 3283369 | 3300 | - | 0.23 | |
DDB_G0294557 | DDB_G0294557 | similar to the cortexillins actin-bundling proteins of the alpha-actininspectrin superfamily | DDB0232430 | CDS | 517463 | 1470 | - | 0.317687 |
DDB_G0295671 | DDB_G0295671 | DDB0232431 | CDS | 4703129 | 1083 | - | 0.237304 | |
DDB_G0295713 | DDB_G0295713 | DDB0232430 | CDS | 4417290 | 2115 | - | 0.249645 | |
abpA | DDB_G0268632 | DDB0232428 | CDS | 2137156 | 2586 | + | 0.361562 | |
abpC | DDB_G0269100 | 120 kDa F-actin binding protein also often called filamin involved in actin cytoskeleton organization motility and development enriched in prestalk cells | DDB0232428 | CDS | 4554019 | 2574 | - | 0.408702 |
abpD | DDB_G0287291 | actin binding protein that is developmentally and cAMP-regulated associates with intracellular membranes | DDB0232432 | CDS | 222824 | 5217 | + | 0.242285 |
act1 | DDB_G0289553 | has 94 | DDB0232432 | CDS | 2938326 | 1131 | - | 0.365164 |
act10 | DDB_G0289811 | has 94 | DDB0232432 | CDS | 3337403 | 1131 | + | 0.415561 |
act11 | DDB_G0288879 | has 94 | DDB0232432 | CDS | 2167534 | 1131 | + | 0.421751 |
act12 | DDB_G0274129 | has 94 | DDB0232429 | CDS | 4718776 | 1131 | - | 0.386384 |
act13 | DDB_G0274599 | has 94 | DDB0232429 | CDS | 4495093 | 1131 | - | 0.41733 |
act14 | DDB_G0274137 | has 94 | DDB0232429 | CDS | 4418543 | 1131 | + | 0.418214 |
act15 | DDB_G0272520 | has 94 | DDB0232429 | CDS | 1781191 | 1131 | + | 0.414677 |
act16 | DDB_G0272248 | has 94 | DDB0232429 | CDS | 1607842 | 1131 | - | 0.392573 |
act17 | DDB_G0274131 | has 80 | DDB0232429 | CDS | 4723516 | 1125 | + | 0.357333 |
act18 | DDB_G0289489 | has 83 | DDB0232432 | CDS | 2886806 | 1143 | + | 0.343832 |
act19 | DDB_G0274727 | has 94 | DDB0232429 | CDS | 4053689 | 1131 | + | 0.399646 |
act2 | DDB_G0274133 | has 94 | DDB0232429 | CDS | 4722018 | 1131 | + | 0.386384 |
act20 | DDB_G0274285 | has 94 | DDB0232429 | CDS | 4047769 | 1131 | - | 0.400531 |
act21 | DDB_G0274561 | has 94 | DDB0232429 | CDS | 4052062 | 1131 | - | 0.399646 |
act22 | DDB_G0275023 | has 94 | DDB0232429 | CDS | 5343575 | 1131 | + | 0.376658 |
act23 | DDB_G0268744 | DDB0232428 | CDS | 2031686 | 1077 | + | 0.36676 | |
act24 | DDB_G0289505 | has 80 | DDB0232432 | CDS | 2876728 | 1134 | + | 0.347443 |
act25 | DDB_G0289507 | has 74 | DDB0232432 | CDS | 2878511 | 1158 | + | 0.337651 |
act26 | DDB_G0269902 | has 64 | DDB0232428 | CDS | 3826453 | 1128 | + | 0.300532 |
act27 | DDB_G0289533 | has 61 | DDB0232432 | CDS | 2880348 | 1119 | + | 0.328865 |
act28 | DDB_G0289511 | contributes to DdPPK2 activity also described as member of the polyphosphate kinase PPK3 family | DDB0232432 | CDS | 2883081 | 1062 | + | 0.335217 |
act29 | DDB_G0286893 | has 56 | DDB0232431 | CDS | 5035700 | 1164 | - | 0.265464 |
act3 | DDB_G0289487 | has 92 | DDB0232432 | CDS | 2884652 | 1131 | + | 0.358974 |
act30_ps | DDB_G0289525 | putative pseudogene contains an actin domain | DDB0232432 | CDS | 2874594 | 1098 | + | 0.343352 |
act31 | DDB_G0269476 | DDB0232428 | CDS | 2844541 | 1068 | + | 0.293071 | |
act32 | DDB_G0269544 | DDB0232428 | CDS | 2967350 | 1179 | - | 0.274809 | |
act33 | DDB_G0287981 | similar to macronuclear actin 1 of ciliates also similar to A. thaliana ACT11 | DDB0232432 | CDS | 925837 | 1245 | - | 0.236948 |
act34_ps | DDB_G0272446 | putative pseudogene contains an incomplete actin domain | DDB0232429 | CDS | 1603869 | 756 | - | 0.366402 |
act35_ps | DDB_G0280749 | putative pseudogene contains a partial actin domain | DDB0232430 | CDS | 3674980 | 336 | + | 0.348214 |
act36_ps | DDB_G0289509 | putative pseudogene contains a partial actin domain | DDB0232432 | CDS | 2881811 | 408 | + | 0.338235 |
act37_ps | DDB_G0280679 | putative pseudogene contains a partial actin domain | DDB0232430 | CDS | 3624484 | 204 | - | 0.377451 |
act38_ps | DDB_G0280883 | putative pseudogene contains a partial actin domain | DDB0232430 | CDS | 3832477 | 267 | + | 0.370787 |
act39_ps | DDB_G0290243 | putative pseudogene contains a partial actin domain | DDB0232432 | CDS | 3768414 | 369 | - | 0.319783 |
act4 | DDB_G0289005 | has 94 | DDB0232432 | CDS | 2234318 | 1131 | - | 0.419982 |
act5 | DDB_G0289663 | has 94 | DDB0232432 | CDS | 3186992 | 1131 | - | 0.419098 |
act6 | DDB_G0274135 | has 94 | DDB0232429 | CDS | 4055916 | 1131 | + | 0.397878 |
act7 | DDB_G0280545 | has 94 | DDB0232430 | CDS | 3684122 | 1131 | + | 0.376658 |
act8 | DDB_G0269234 | has 94 | DDB0232428 | CDS | 4602557 | 1131 | + | 0.425287 |
act9 | DDB_G0274601 | has 94 | DDB0232429 | CDS | 4455464 | 1131 | + | 0.419098 |
arpA | DDB_G0288937 | centrosome-associated actin homolog contributes to the dynactin complex contributes to DdPPK2 activity also described as member of the polyphosphate kinase PPK3 family | DDB0232432 | CDS | 2149735 | 1152 | - | 0.329861 |
arpB | DDB_G0272106 | component of the Dictyostelium Arp2Arp3 complex contributes to DdPPK2 activity also described as member of the polyphosphate kinase PPK3 family | DDB0232429 | CDS | 1646887 | 1179 | - | 0.398643 |
arpC | DDB_G0283755 | component of the Dictyostelium Arp2Arp3 complex | DDB0232431 | CDS | 1135639 | 1257 | - | 0.381862 |
arpD | DDB_G0280887 | ortholog of A. thaliana ARP4 and very similar to the mammalian actin-like protein 6A which is involved in transcriptional activation and repression of select genes by chromatin remodelling | DDB0232430 | CDS | 3833482 | 1323 | + | 0.297808 |
arpE | DDB_G0291728 | ortholog of the conserved actin related protein ARP5 in mammalian named ACTR5 the yeast protein is a nuclear actin-related protein involved in chromatin remodelingbr bNomenclature conflict:b Do not confuse this gene with arcB the 34 kDa component of the Arp2Arp3 complex. | DDB0232433 | CDS | 714429 | 2055 | + | 0.287591 |
arpF | DDB_G0287007 | ortholog of the conserved actin related protein ARP6 in mammalian called ACTR6 a putative component of a chromatin-remodeling complex | DDB0232431 | CDS | 5196102 | 1473 | + | 0.260014 |
arpH | DDB_G0287739 | similar to mammalian and yeast actin related protein 10 part of the dynactin complex | DDB0232432 | CDS | 636584 | 1428 | - | 0.238095 |
calA | DDB_G0279407 | calcium-dependent regulatory protein involved in cytokinesis regulated by cytosolic Ca2 fluxes allowing differential binding to target CaM binding proteins (CaMBPs) binds several proteins among them nuclear NumA and Cdk5 | DDB0232430 | CDS | 2244074 | 459 | - | 0.35512 |
calB | DDB_G0269104 | DDB0232428 | CDS | 2981116 | 450 | + | 0.275556 | |
cbpL | DDB_G0288785 | putative Ca2-binding protein with 4 putative EF-hands belongs to the frequenins a family of myristoyl-switch calcium-binding proteins | DDB0232432 | CDS | 1964055 | 576 | + | 0.258681 |
cbpM | DDB_G0286371 | putative Ca2-binding protein with 4 putative EF-hands belongs to the frequenins a family of myristoyl-switch calcium-binding proteins | DDB0232431 | CDS | 4370399 | 552 | - | 0.277174 |
cenA | DDB_G0288427 | similar to human Centrin 2 EF-hand protein localizes to the centromer from which it dissociates during mitosis | DDB0232432 | CDS | 1525659 | 456 | + | 0.245614 |
cenB | DDB_G0279151 | centrin required for nuclear and centrosome stability localizes to the nucleus in interphase but not during mitosis and is involved in the centrosome cycle | DDB0232430 | CDS | 1697579 | 453 | - | 0.258278 |
cnbA | DDB_G0267446 | regulatory subunit of the Casup2supcalmodulin-dependent serinethreonine protein phosphatase contains an EF-hand calcium binding motif | DDB0232428 | CDS | 816934 | 1041 | - | 0.26513 |
cnbB | DDB_G0285999 | contains 3 EF-hands similar to calcineurin B (cnbA) the regulatory subunit of the Ca2calmodulin-dependent serinethreonine protein phosphatase | DDB0232431 | CDS | 3918232 | 552 | + | 0.269928 |
ctxA | DDB_G0289483 | member of the alpha-actininspectrin superfamily dimerizes with cortexillin II involved in cytokinesis and development and associates with the actin cytoskeleton | DDB0232432 | CDS | 2847194 | 1335 | - | 0.347566 |
ctxB | DDB_G0276893 | member of the alpha-actininspectrin superfamily dimerizes with cortexillin I involved in cytokinesis and development and associates with the actin cytoskeleton | DDB0232429 | CDS | 7304770 | 1326 | - | 0.3454 |
dhcA | DDB_G0276355 | DDB0232429 | CDS | 6681538 | 14193 | - | 0.337631 | |
eb1 | DDB_G0283607 | DDB0232431 | CDS | 912876 | 1521 | + | 0.326759 | |
fia | DDB_G0284389 | composed of a DUF292 domain at the amino terminus two filaminABP280 repeats and an actin domain at the carboxyl terminus | DDB0232431 | CDS | 1932445 | 2835 | - | 0.337919 |
fimA | DDB_G0277855 | calcium-regulated actin bundling protein binds F-actin enriched in gametes | DDB0232430 | CDS | 187950 | 1833 | - | 0.346427 |
fimC | DDB_G0278545 | contains 4 calponin homology (CH) domains two CH domains constitute one actin binding domain | DDB0232430 | CDS | 1046298 | 3642 | - | 0.266337 |
fimD | DDB_G0270762 | contains 4 calponin homology (CH) domains two CH domains constitute one actin binding domain | DDB0232428 | CDS | 4467278 | 5145 | + | 0.230709 |
gacGG | DDB_G0280093 | DDB0232430 | CDS | 2923710 | 3612 | - | 0.295958 | |
gefC | DDB_G0282381 | DDB0232430 | CDS | 6243320 | 4374 | - | 0.299268 | |
gxcB | DDB_G0269424 | DDB0232428 | CDS | 2732721 | 3597 | - | 0.263553 | |
gxcCC | DDB_G0279123 | contains two actin binding domains a putative calmodulin binding domain and a Dbl homology (DH) domain specific for Rho guanine nucleotide exchange factors (GEF) | DDB0232430 | CDS | 1613622 | 3438 | + | 0.3121 |
gxcZ | DDB_G0293928 | DDB0232433 | CDS | 3506582 | 3087 | - | 0.259475 | |
iqgD | DDB_G0275731 | similar to RasGAP proteins contains one calponin homology domain and one rasGAP domain | DDB0232429 | CDS | 5940660 | 4158 | - | 0.309524 |
kif1 | DDB_G0290963 | ortholog of C. elegans Unc104 and mammalian KIF1A involved in intracellular transport | DDB0232432 | CDS | 4896037 | 6618 | - | 0.316863 |
kif10 | DDB_G0293198 | DDB0232433 | CDS | 2654607 | 3717 | - | 0.262039 | |
kif11 | DDB_G0291039 | DDB0232432 | CDS | 4850945 | 2058 | - | 0.306122 | |
kif12 | DDB_G0268258 | MKLP1 subfamily kinesin required for cell division in suspension and for nuclei separation during karyokinesis localized in the nucleus during interphase and in the centrosome spindle and spindle midbody during cytokinesis | DDB0232428 | CDS | 1654404 | 4500 | + | 0.277333 |
kif13 | DDB_G0288361 | belongs to the BimCEg5 subfamily predicted to play a role in mitosis | DDB0232432 | CDS | 1422250 | 3798 | + | 0.28673 |
kif2 | DDB_G0267396 | belongs to the NCDKar3 subfamily predicted to play a role in mitosis | DDB0232428 | CDS | 351991 | 2379 | - | 0.286255 |
kif3 | DDB_G0280967 | kinesin-1 family protein involved in intracellular transport belongs to the kinesin KHC subfamily | DDB0232430 | CDS | 4109358 | 3582 | + | 0.303183 |
kif4 | DDB_G0285101 | belongs to the CENP-E subfamily predicted to play a role in mitosis has a putative nuclear localization signal C-terminal to its motor domain | DDB0232431 | CDS | 2856191 | 5769 | + | 0.268677 |
kif5 | DDB_G0276369 | kinesin-1 family protein belongs to the kinesin KHC subfamily binds microtubules in an ATP-dependent manner and bundles actin in vitro | DDB0232429 | CDS | 6648064 | 2973 | + | 0.282879 |
kif6 | DDB_G0267404 | belongs to the MCAKKif2 subfamily contains 1 SAM domain predicted to play a role in mitosis | DDB0232428 | CDS | 1747506 | 3093 | - | 0.282897 |
kif7 | DDB_G0281555 | DDB0232430 | CDS | 4819674 | 3768 | + | 0.286359 | |
kif8 | DDB_G0284471 | DDB0232431 | CDS | 2103969 | 5622 | - | 0.284596 | |
kif9 | DDB_G0274603 | DDB0232429 | CDS | 4280121 | 3669 | - | 0.275279 | |
mhcA | DDB_G0286355 | myosin II heavy chain component of the actin-based molecular motor (conventional myosin) has actin-activated ATPase activity myosin II consists of two heavy chains and one essential (mlcE) and one regulatory light chain (mlcR) respectively | DDB0232431 | CDS | 4451077 | 6351 | + | 0.377893 |
mlcC | DDB_G0289563 | light chain that binds to the neck region of myoC contains two calcium-binding EF-hand motifs but does not bind calcium | DDB0232432 | CDS | 2954406 | 225 | - | 0.311111 |
mlcD | DDB_G0277917 | DDB0232430 | CDS | 607477 | 444 | + | 0.304054 | |
mlcE | DDB_G0277859 | component of actin-based molecular motor myosin II (conventional myosin) component | DDB0232430 | CDS | 76885 | 453 | + | 0.364238 |
mlcR | DDB_G0276077 | component of actin-based molecular motor myosin II (conventional myosin) component | DDB0232429 | CDS | 6426413 | 486 | + | 0.31893 |
myoA | DDB_G0280039 | actin-based motor unconventional myosin heavy chain | DDB0232430 | CDS | 3224159 | 2985 | - | 0.305863 |
myoB | DDB_G0289117 | long tailed class-1 myosin a molecular motor protein that localizes to actin-rich structures at the leading edge of migrating cells | DDB0232432 | CDS | 2410248 | 3336 | + | 0.351619 |
myoC | DDB_G0276617 | DDB0232429 | CDS | 7046886 | 3549 | - | 0.351085 | |
myoD | DDB_G0275447 | class I (unconventiona) myosin component of actin-based molecular motor | DDB0232429 | CDS | 5600309 | 3330 | + | 0.351652 |
myoE | DDB_G0288679 | (unconventional) class I myosin fast motor molecule involved in phagocytosis | DDB0232432 | CDS | 1829072 | 3018 | - | 0.336978 |
myoF | DDB_G0289177 | DDB0232432 | CDS | 2531958 | 3216 | - | 0.28607 | |
myoG | DDB_G0276363 | required for cell polarity and chemotaxis to cAMP plays a role in mediating early chemotactic signalling contains an N-terminal motor domain two MyTH4 domains an IQ calmodulin-binding region and a SH3 domain | DDB0232429 | CDS | 6748878 | 10341 | + | 0.289237 |
myoH | DDB_G0289447 | DDB0232432 | CDS | 2840200 | 5316 | - | 0.258653 | |
myoI | DDB_G0274455 | similar to the conserved MYO7A unconventional myosin required in Dictyostelium for phagocytosis and substrate adhesion | DDB0232429 | CDS | 4534415 | 7074 | + | 0.326972 |
myoJ | DDB_G0272112 | conditional processive motor protein that can move over long distances along F-actin without disassociating processiveness depends on high physiological Mgsup2sup concentrations | DDB0232429 | CDS | 1452059 | 6738 | + | 0.309884 |
myoK | DDB_G0274575 | class 1 myosin lacking the traditional tail domains common to short-tailed myosins binds actin and is in complex with several other proteins involved in phagocytosis maintenance of cortical tension and motility | DDB0232429 | CDS | 3960245 | 2577 | + | 0.353124 |
myoM | DDB_G0292262 | unconventional myosin and guanyl-nucleotide exchange factor which acts on Rac1A Rac1B and human Rac1 but not on RacC and RacE | DDB0232433 | CDS | 1463619 | 5214 | + | 0.274262 |
ncsA | DDB_G0275931 | contains four EF-hands belongs to the frequenins a family of myristoyl-switch calcium-binding proteins | DDB0232429 | CDS | 6088223 | 561 | - | 0.279857 |
tbcD | DDB_G0268516 | DDB0232428 | CDS | 802089 | 4443 | + | 0.238352 | |
tirA | DDB_G0289237 | DDB0232432 | CDS | 2526970 | 4011 | - | 0.222638 | |
tubA | DDB_G0287689 | monomeric subunit of microtubules as most other species Dicty has two alpha-tubulin genes and only one of each beta- and gamma-tubulin the other alpha tubulin gene is | DDB0232432 | CDS | 707217 | 1374 | - | 0.381368 |
tubA2 | DDB_G0281889 | bCommunity annotationb: As most other species Dicty has two alpha-tubulin genes and only one of each beta- and gamma-tubulin. Dicty's two alpha tubulin genes are both moderately upregulated in the Dicty rblA disruptant but tubA2 is substantially more so. In development tubA2 shows an expression trajectory approximating that of mitotic genes while tubA does not. The promoter of tubA2 contains a likely E2F binding sequence (ATTGGCGCT). It is possible but perhaps not compelling that tubA2 has specific mitotic functions. Harry MacWilliams July 2010br | DDB0232430 | CDS | 5074777 | 1359 | + | 0.293598 |
tubB | DDB_G0269196 | DDB0232428 | CDS | 3261649 | 1368 | - | 0.388889 | |
tubC | DDB_G0271738 | DDB0232429 | CDS | 727031 | 1389 | + | 0.332613 |