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2024-05-19 18:17:59

Gene list

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COG category: Intracellular trafficking and secretion
Organism: Dictyostelium discoideum AX4, AX4

Number of genes found: 116

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Show UniProt / TrEMBL protein name View in Fasta format (DNA) View in Fasta format (Protein)  

 
Dictyostelium discoideum AX4, AX4
NameLocus tagProduct / DescriptionGenomic elementTypeBeginLengthStrandGC-content
DDB_G0267538 DDB_G0267538 DDB0232428 CDS291771 1824 + 0.313596
DDB_G0269942 DDB_G0269942 belongs to the synaptobrevin family ortholog of human SEC22B contains a longin domain and a v-snare coiled-coil domain contains 1 predicted transmembrane domainDDB0232428 CDS3911017 645 + 0.24031
DDB_G0271044 DDB_G0271044 contains Sec23Sec24 zinc finger trunk and helical domains yeast Sec23Sec24 is a component of COPII (coat protein complex II) involved in ER to Golgi transportDDB0232428 CDS4346844 2391 - 0.26056
DDB_G0272318 DDB_G0272318 functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC) contains a N-terminal importin beta binding domain (IBB domain)DDB0232429 CDS1278811 1551 + 0.350097
DDB_G0272594_ps DDB_G0272594 putative pseudogene very similar to the putative importin subunit alpha C gene DDB0232429 CDS2405347 747 - 0.293173
DDB_G0273149 DDB_G0273149 functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC) contains a N-terminal importin beta binding domain (IBB domain) there is a second copy of this gene DDB0232429 CDS2875789 1653 - 0.333333
DDB_G0273467 DDB_G0273467 there is a second copy of this gene DDB0232429 CDS2890795 429 + 0.2331
DDB_G0273579 DDB_G0273579 there is a second copy of this gene DDB0232429 CDS3140434 429 - 0.2331
DDB_G0273595 DDB_G0273595 functions in nuclear protein import via a substrate-importin alpha-beta transport complex that passes though the nuclear pore complexes (NPC) contains a N-terminal importin beta binding domain (IBB domain) there is a second copy of this gene DDB0232429 CDS3154181 1653 + 0.333333
DDB_G0274789 DDB_G0274789 DDB0232429 CDS3841237 6309 + 0.277223
DDB_G0274813 DDB_G0274813 conserved protein mainly among fungi and plantsDDB0232429 CDS3971713 2817 + 0.302449
DDB_G0275571 DDB_G0275571 DDB0232429 CDS5522231 2793 + 0.3029
DDB_G0275603 DDB_G0275603 DDB0232429 CDS5583526 1782 + 0.319865
DDB_G0275843 DDB_G0275843 DDB0232429 CDS5657920 2226 - 0.310422
DDB_G0276239 DDB_G0276239 involved in vesicle-mediated transport similar to VPS33 DDB0232429 CDS6373737 2577 - 0.217307
DDB_G0276625 DDB_G0276625 belongs to the drugmetabolite transporter superfamily similar to human SLC35D1 (UDP-glucuronic acidUDP-N-acetylgalactosamine transporter) and S. cerevisiae VRG4 (GDP-mannose transporter 1) contains 8 putative transmembrane domainsDDB0232429 CDS7055459 945 - 0.271958
DDB_G0277537 DDB_G0277537 subunit of PI4K responsible for the phosphorylation of phosphatidylinositol (PI) to PI4P (ATP 1-phosphatidyl-1D-myo-inositol ADP 1-phosphatidyl-1D-myo-inositol 4-phosphate) the first committed step in the generation of phosphatidylinositol 45-bisphosphate (PIP2) a precursor of the second messenger inositol 145-trisphosphate (InsP3)DDB0232429 CDS7989159 7383 + 0.301233
DDB_G0277993 DDB_G0277993 importins function in nuclear protein import however this protein does not contain the N-terminal importin beta binding domain (IBB domain)DDB0232430 CDS126886 1575 + 0.31873
DDB_G0278143 DDB_G0278143 DDB0232430 CDS347205 6408 + 0.302903
DDB_G0278267 DDB_G0278267 DDB0232430 CDS586381 2631 + 0.259597
DDB_G0278333 DDB_G0278333 DDB0232430 CDS713907 1950 - 0.315385
DDB_G0278631 DDB_G0278631 putative ortholog of H. sapiens SLC35D2 UDP-N-acetylglucosamineUDP-glucoseGDP-mannose transporter contains 10 putative transmembrane domainsDDB0232430 CDS462648 1149 + 0.222802
DDB_G0278773 DDB_G0278773 similar to human VAPA and VAPB defects in VAPB cause amyotrophic lateral sclerosis 8 (ALS8)DDB0232430 CDS1149897 933 - 0.276527
DDB_G0278973 DDB_G0278973 DDB0232430 CDS1448552 1845 - 0.197832
DDB_G0280525 DDB_G0280525 DDB0232430 CDS3381127 4614 + 0.252492
DDB_G0281627 DDB_G0281627 DDB0232430 CDS4725130 1827 + 0.305419
DDB_G0282017 DDB_G0282017 involved in vesicle-mediated transport similar to VPS33 DDB0232430 CDS5245886 1944 + 0.237654
DDB_G0283011 DDB_G0283011 DDB0232431 CDS151994 360 - 0.286111
DDB_G0284149 DDB_G0284149 ortholog of yeast VID24 a peripheral membrane protein located at Vid (vacuole import and degradation) vesiclesDDB0232431 CDS1533705 699 - 0.296137
DDB_G0286479 DDB_G0286479 DDB0232431 CDS4506469 3504 - 0.257991
DDB_G0286695 DDB_G0286695 DDB0232431 CDS4856852 735 - 0.285714
DDB_G0288079_ps DDB_G0288079 similar to DDB_G0277993 a protein of the importin familyDDB0232432 CDS1063770 1194 - 0.326633
DDB_G0288849 DDB_G0288849 contains a predicted signal peptide and a putative C-terminal transmembrane domain similar to S. cerevisiae ERO1 (endoplasmic oxidoreductin-1) which is required for the formation of disulfide bonds in the proteins in the endoplasmic reticulumDDB0232432 CDS2057527 1662 - 0.253309
DDB_G0290341 DDB_G0290341 similar to S. cerevisiae SFT2 contains 4 putative transmembrane domains similar to D. purpureum proteinDDB0232432 CDS3989030 621 - 0.259259
DDB_G0291055 DDB_G0291055 homolog of human SFT2D1 (SFT2 domain-containing protein 1) contains 4 putative transmembrane domainsDDB0232432 CDS4835830 477 + 0.295597
DDB_G0291406 DDB_G0291406 DDB0232433 CDS260638 12408 + 0.230819
DDB_G0292148 DDB_G0292148 DDB0232433 CDS1273206 1569 - 0.262588
DDB_G0293328 DDB_G0293328 DDB0232433 CDS2760211 396 + 0.39899
DDB_G0293622 DDB_G0293622 DDB0232433 CDS3159608 2976 + 0.290995
DDB_G0293712 DDB_G0293712 DDB0232433 CDS3080260 564 + 0.281915
acapA DDB_G0279649 plays a role in cytokinesis cell migration and actin cytoskeleton dynamics hydrolyzes GTP bound to ArfA in vitroDDB0232430 CDS2363863 4002 + 0.31959
acapB DDB_G0276395 similar to mammalian Acap3 hydrolyzes GTP bound to ArfA in vitroDDB0232429 CDS6763233 2532 + 0.265798
ap1b1 DDB_G0279141 highly similar to AP-1 complex subunit beta-1 (AP1B1) and AP-2 complex subunit beta-1 (AP2B1) which play a role in clathrin-dependent protein sortingDDB0232430 CDS1680228 2829 - 0.331212
ap1s1 DDB_G0279359 DDB0232430 CDS1984933 471 + 0.26327
ap1s2 DDB_G0295711 DDB0232433 CDS619891 465 - 0.260215
ap2s1 DDB_G0289721 DDB0232432 CDS3163717 429 - 0.261072
ap3b-1 DDB_G0272578 there is a second copy of this gene DDB0232429 CDS2374895 3327 - 0.285843
ap3b-2 DDB_G0274003 there is a second copy of this gene DDB0232429 CDS3652959 3327 + 0.285843
ap3s1 DDB_G0275405 DDB0232429 CDS5412017 516 - 0.226744
ap4b1 DDB_G0283319 putative ortholog of H. sapiens AP4B1 member of a complex that mediates protein sortingDDB0232431 CDS525048 2517 + 0.247517
ap4e1 DDB_G0280427 DDB0232430 CDS3335352 3243 - 0.254702
ap4s1 DDB_G0284905 DDB0232431 CDS2625777 420 - 0.240476
atr1 DDB_G0291380 atypical PIKK family protein kinase similar to protein kinase ATR which modulates cell cycle progression and DNA repair in other organisms ATR phosphorylates Rad17 histone H2AX p53 and Nbs1DDB0232433 CDS214264 9474 - 0.259552
copB DDB_G0284735 beta subunit of the coatomer complex essential for the secretory pathway colocalizes with comitin at the GolgiDDB0232431 CDS2394561 2739 + 0.316174
copG DDB_G0289371 DDB0232432 CDS2724036 2697 + 0.309974
crsA DDB_G0282607 catalyzes the reaction acyl-CoA sphingosine CoA N-acylsphingosine in ceramide synthesis ortholog of S. cerevisiae LAG1 and H. sapiens TRH1DDB0232430 CDS5996864 1026 - 0.273879
dnapkcs DDB_G0281167 atypical PIKK family protein kinase similar to human DNA-PKcs required for the repair of DNA double-strand breaks belongs to the PIKK family of protein kinasesDDB0232430 CDS4132807 12900 + 0.265504
exoc3 DDB_G0293520 subunit of the exocyst complex which targets secretory vesicles to active sites of exocytosisDDB0232433 CDS2981805 2352 + 0.274235
gacC DDB_G0284571 DDB0232431 CDS2170033 1200 - 0.288333
golt1 DDB_G0292868 conserved protein might be involved in fusion of ER-derived transport vesicles with the Golgi complexDDB0232433 CDS2183910 417 - 0.270983
grpA DDB_G0293248 involved in the unconventional secretory pathway of acbA the precurser of SDF-2 (spore differentiation factor 2) ortholog of the mammalian golgi reassembly stacking protein 2 (golgi reassembly-stacking protein of 55 kDa)DDB0232433 CDS2631684 984 + 0.311992
gxcDD DDB_G0279733 multifunctional protein containing a Rac exchange factor domain an Arf GTPase activating domain a CH domain two IQ motifs and three PH domainsDDB0232430 CDS2433796 9348 + 0.295892
immp DDB_G0283049 in other organisms there are two subunits for this enzyme with relatively high sequence similarity to each other Dictyostelium appear to have a single geneDDB0232431 CDS142399 972 + 0.220165
kdelr DDB_G0272124 endoplasmic reticulum receptor for the KDEL signal sequence of proteins resident in the endoplasmic reticulum believed to cycle between the cis side of the Golgi apparatus and the ERDDB0232429 CDS1376821 657 - 0.25723
nup155 DDB_G0291163 component of the nuclear pore complex may be involved both in binding and translocating proteinsDDB0232432 CDS5077769 4728 - 0.271151
oxaA DDB_G0284883 similar to OXA1 a conserved inner mitochondrial membrane protein that is required for the activity and assembly of cytochrome oxidase and for the insertion of integral membrane proteins into the mitochondrial inner membrane there is a second putative oxidase assembly protein in D. discoideum DDB0232431 CDS2586982 1191 + 0.260285
oxaB DDB_G0281171 similar to OXA1 a conserved inner mitochondrial membrane protein that is required for the activity and assembly of cytochrome oxidase and for the insertion of integral membrane proteins into the mitochondrial inner membrane there is a second putative oxidase assembly protein in D. discoideum DDB0232430 CDS4148918 1257 - 0.275259
pex5 DDB_G0286033 ortholog of peroxin 5 peroxisomal membrane signal receptor for C-terminal tripeptide signal sequence (PTS1) of peroxisomal matrix proteins required for peroxisomal matrix protein importmutations in human homolog cause a variety of peroxisomal disordersDDB0232431 CDS3973237 1926 - 0.336449
pikA DDB_G0278727 DDB0232430 CDS1154369 4716 + 0.261026
pikB DDB_G0283081 DDB0232431 CDS247398 5574 - 0.311805
pikC DDB_G0275011 DDB0232429 CDS5211773 5094 + 0.270907
pikD DDB_G0288485 subunit of PI4K responsible for the phosphorylation of phosphatidylinositol (PI) to PI4P (ATP 1-phosphatidyl-1D-myo-inositol ADP 1-phosphatidyl-1D-myo-inositol 4-phosphate) the first committed step in the generation of phosphatidylinositol 45-bisphosphate (PIP2) a precursor of the second messenger inositol 145-trisphosphate (InsP3)DDB0232432 CDS1616073 3543 + 0.269828
pikE DDB_G0289601 ortholog of yeast VPS34 a phosphatidylinositol 3-kinaseDDB0232432 CDS3005109 2451 - 0.299878
pikF DDB_G0268548 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase rasDDB0232428 CDS1099622 4149 + 0.291396
pikG DDB_G0282625 putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring has the capacity to bind and be activated by the GTP-bound small GTPase rasDDB0232430 CDS6013022 5016 - 0.234649
pikH DDB_G0291093 putative PI3k putative PI3K that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring unlike other PI3Ks does not contain a ras binding domain but a PH domain and does not localize to the cell cortex upon chemotactic stimulationDDB0232432 CDS4980832 5463 - 0.242541
prafA DDB_G0278887 belongs to a conserved family of multi-pass transmembrane proteins contains 3 predicted transmembrane domainsDDB0232430 CDS1342274 708 - 0.303672
ranbp1 DDB_G0287391 DDB0232432 CDS246455 585 + 0.353846
rer1 DDB_G0292588 conserved protein involved in the retrieval of some endoplasmic reticulum membrane proteins from the early golgi compartment contains 3 predicted transmembrane domainsDDB0232433 CDS1815723 567 - 0.292769
scfd1 DDB_G0288719 DDB0232432 CDS1870694 2022 - 0.271019
sec1 DDB_G0283937 highly similar to mammalian Sec1 (also known as syntaxin binding protein 1) which plays a role in vesicle transport by binding to t-SNAREs expressed in prespore cells involved in osmoregulation and hence cell motilityDDB0232431 CDS1335851 1797 + 0.329994
sec23 DDB_G0281985 DDB0232430 CDS5216752 2253 + 0.376831
sec24 DDB_G0281255 DDB0232430 CDS4298212 3042 + 0.359303
sec24l DDB_G0277797 component of COPII (coat protein complex II) involved in ER to Golgi transport similar to SEC24C and SEC24DDDB0232429 CDS8422539 3402 + 0.357731
sec61a DDB_G0278885 alpha subunit of the SEC61 complex (composed of DDB0232430 CDS1338636 1428 - 0.366947
sec61g DDB_G0287777 gamma subunit of the SEC61 complex (composed of DDB0232432 CDS682723 210 + 0.328571
sec63 DDB_G0286131 similar to the widely conserved SEC63 which seems to be required for integral membrane and secreted preprotein translocation across the endoplasmic reticulum membraneDDB0232431 CDS4064803 2445 - 0.350102
smg1 DDB_G0275845 atypical PIKK family protein kinase similar to the PI-3-kinase-related kinase SMG1 which functions in nonsense-mediated mRNA decay belongs to the PIKK family of protein kinasesDDB0232429 CDS5665840 7035 + 0.267235
srp19 DDB_G0275211 component of the signal recognition particle (SRP) which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulumDDB0232429 CDS5011473 537 + 0.312849
srp54 DDB_G0275455 component of the signal recognition particle (SRP) which ensures correct targeting of nascent secretory proteins to the endoplasmic reticulumDDB0232429 CDS6110111 1629 - 0.361572
srpR DDB_G0277377 DDB0232429 CDS7920699 1848 - 0.308983
syn16A DDB_G0276575 similar to syntaxin 16 a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusionDDB0232429 CDS6993306 945 + 0.256085
syn16B DDB_G0276469 similar to syntaxin 16 a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusionDDB0232429 CDS6988936 1008 + 0.249008
syn1A DDB_G0289379 similar to syntaxin 1 a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusionDDB0232432 CDS2678322 1002 - 0.297405
syn1B DDB_G0270556 similar to syntaxin 1 a subfamily of the SNARE family (Soluble NSF Attachment Protein REceptor) involved in vesicle fusionDDB0232428 CDS2999912 1005 + 0.250746
syn7A DDB_G0287733 member of the SNARE family (Soluble NSF Attachment Protein REceptor) plays a role in endosomal fusionDDB0232432 CDS617723 1071 + 0.289449
tipC DDB_G0267422 similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retention in D. discoideum involved in early development and tip formationDDB0232428 CDS1494431 11547 + 0.250108
tnpo DDB_G0269948 homolog of H. sapiens TNPO12 and S. cervisiae KAP104 (karyopherin 104) involved in nuclear protein importDDB0232428 CDS3916816 2796 + 0.327253
tor DDB_G0281569 atypical PIKK family FRAP subfamily protein kinase ortholog of tor a protein kinase that plays a central role in response to nutrients stress and intracellular energy state called mTOR in mammals in dTOR in Drosophila DDB0232430 CDS4934791 7143 - 0.347893
trappc4 DDB_G0280827 ortholog of the trafficking protein particle complex subunit 4 part of the multisubunit TRAPP (transport protein particle) complexDDB0232430 CDS1440057 408 - 0.272059
trappc5 DDB_G0278643 homolog of human TRAPPC5 a component of the multisubunit TRAPP (transport protein particle) complex which may play a role in vesicular transport from endoplasmic reticulum to GolgiDDB0232430 CDS551038 561 + 0.286988
vamp7A DDB_G0284951 member of the SNARE family (Soluble NSF Attachment Protein REceptor) localizes to endosome and interacts with syn7ADDB0232431 CDS2678890 651 + 0.288786
vamp7B DDB_G0277173 SNARE protein interacts with AP180 (clmA) which retrieves Vamp7B from the contractile vacuoleDDB0232429 CDS7680323 783 + 0.297573
vps13A DDB_G0286725 putative ortholog of S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retentionDDB0232431 CDS4889609 10122 - 0.30488
vps13B DDB_G0274917 similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retentionDDB0232429 CDS4457216 18186 - 0.252777
vps13D DDB_G0286545 weakly similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retentionDDB0232431 CDS4616198 13779 - 0.252994
vps13E DDB_G0268886 weakly similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retentionDDB0232428 CDS2311232 12726 + 0.274399
vps13F DDB_G0287055 weakly similar to S. cerevisiae VPS13 involved in vacuolar protein sorting and protein-Golgi retentionDDB0232431 CDS5237174 12741 - 0.271172
vps33 DDB_G0291097 DDB0232432 CDS4992025 1935 - 0.328165
vps45 DDB_G0290213 putative ortholog of VPS45 involved in vacuolar protein sortingDDB0232432 CDS3802462 1692 - 0.278369
vps5 DDB_G0272989 putative ortholog of mammalian sorting nexin and S. cerevisiae VPS5 a subunit of the membrane-associated retromer complex essential for endosome-to-Golgi retrograde transportDDB0232429 CDS2025586 1638 - 0.339438
xpo1 DDB_G0291306 DDB0232433 CDS102439 3174 - 0.3431
xpo5 DDB_G0284379 DDB0232431 CDS1912156 3408 - 0.289319
yipf5 DDB_G0283541 very similar to Yip1 domain family member 5 (YIPF5) in yeast YIP1 localizes to the Golgi and interacts with GTPases contains four putative transmembrane domainsDDB0232431 CDS791068 639 + 0.273865
yipf6 DDB_G0282825 very similar to Yip1 domain family member 6 (YIPF6) in yeast YIP1 localizes to the Golgi and interacts with GTPases contains five putative transmembrane domainsDDB0232430 CDS6266209 549 - 0.300546
ykt6 DDB_G0291656 DDB0232433 CDS180176 609 + 0.320197